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o-aminophenol oxidase

o-Aminophenol oxidase (EC 1.10.3.4, isophenoxazine synthase, o-aminophenol:O2 oxidoreductase, 2-aminophenol:O2 oxidoreductase, GriF) is an enzyme with systematic name 2-aminophenol:oxygen oxidoreductase.[1][2][3][4] This enzyme catalyses the following chemical reaction

o-Aminophenol oxidase
Identifiers
EC no.1.10.3.4
CAS no.9013-85-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
2 o-aminophenol + O2 + acceptor ⇌ 2-aminophenoxazin-3-one + reduced acceptor + 2 H2O (overall reaction)
(1a) 2 2-aminophenol + O2 ⇌ 2 6-iminocyclohexa-2,4-dienone + 2 H2O
(1b) 2 6-iminocyclohexa-2,4-dienone + acceptor ⇌ 2-aminophenoxazin-3-one + reduced acceptor (spontaneous)

o-Aminophenol oxidase is a flavoprotein.

References edit

  1. ^ Nair PM, Vaidyanathan CS (March 1964). "Isophenoxazine synthase". Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects. 81 (3): 507–16. doi:10.1016/0926-6569(64)90135-x. PMID 14170322.
  2. ^ Nair PM, Vining LC (February 1965). "Isophenoxazine synthase apoenzyme from Pycnoporus coccineus". Biochimica et Biophysica Acta (BBA) - Enzymology and Biological Oxidation. 96 (2): 318–27. doi:10.1016/0926-6593(65)90015-9. PMID 14298835.
  3. ^ Subba Rao PV, Vaidyanathan CS (February 1967). "Studies on the metabolism of o-aminophenol. Purification and properties of isophenoxazine synthase from Bauhenia monandra". Archives of Biochemistry and Biophysics. 118 (2): 388–94. doi:10.1016/0003-9861(67)90365-7. PMID 4166439.
  4. ^ Suzuki H, Furusho Y, Higashi T, Ohnishi Y, Horinouchi S (January 2006). "A novel o-aminophenol oxidase responsible for formation of the phenoxazinone chromophore of grixazone". The Journal of Biological Chemistry. 281 (2): 824–33. doi:10.1074/jbc.M505806200. PMID 16282322.

External links edit

aminophenol, oxidase, aminophenol, oxidase, isophenoxazine, synthase, aminophenol, oxidoreductase, aminophenol, oxidoreductase, grif, enzyme, with, systematic, name, aminophenol, oxygen, oxidoreductase, this, enzyme, catalyses, following, chemical, reactiono, . o Aminophenol oxidase EC 1 10 3 4 isophenoxazine synthase o aminophenol O2 oxidoreductase 2 aminophenol O2 oxidoreductase GriF is an enzyme with systematic name 2 aminophenol oxygen oxidoreductase 1 2 3 4 This enzyme catalyses the following chemical reactiono Aminophenol oxidaseIdentifiersEC no 1 10 3 4CAS no 9013 85 8DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumSearchPMCarticlesPubMedarticlesNCBIproteins 2 o aminophenol O2 acceptor 2 aminophenoxazin 3 one reduced acceptor 2 H2O overall reaction 1a 2 2 aminophenol O2 2 6 iminocyclohexa 2 4 dienone 2 H2O 1b 2 6 iminocyclohexa 2 4 dienone acceptor 2 aminophenoxazin 3 one reduced acceptor spontaneous o Aminophenol oxidase is a flavoprotein References edit Nair PM Vaidyanathan CS March 1964 Isophenoxazine synthase Biochimica et Biophysica Acta BBA Specialized Section on Enzymological Subjects 81 3 507 16 doi 10 1016 0926 6569 64 90135 x PMID 14170322 Nair PM Vining LC February 1965 Isophenoxazine synthase apoenzyme from Pycnoporus coccineus Biochimica et Biophysica Acta BBA Enzymology and Biological Oxidation 96 2 318 27 doi 10 1016 0926 6593 65 90015 9 PMID 14298835 Subba Rao PV Vaidyanathan CS February 1967 Studies on the metabolism of o aminophenol Purification and properties of isophenoxazine synthase from Bauhenia monandra Archives of Biochemistry and Biophysics 118 2 388 94 doi 10 1016 0003 9861 67 90365 7 PMID 4166439 Suzuki H Furusho Y Higashi T Ohnishi Y Horinouchi S January 2006 A novel o aminophenol oxidase responsible for formation of the phenoxazinone chromophore of grixazone The Journal of Biological Chemistry 281 2 824 33 doi 10 1074 jbc M505806200 PMID 16282322 External links editO aminophenol oxidase at the U S National Library of Medicine Medical Subject Headings MeSH Portal nbsp Biology Retrieved from https en wikipedia org w index php title O aminophenol oxidase amp oldid 1172355713, wikipedia, wiki, book, books, library,

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