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Wikipedia

Nucleolar phosphoprotein p130

May 01, 2024

Nucleolar phosphoprotein p130 is a protein that in humans is encoded by the NOLC1 gene.[3][4][5]

NOLC1
Identifiers
AliasesNOLC1, NOPP130, NOPP140, NS5ATP13, P130, Nucleolar phosphoprotein p130, nucleolar and coiled-body phosphoprotein 1, Srp40
External IDsOMIM: 602394 HomoloGene: 68818 GeneCards: NOLC1
Orthologs
SpeciesHumanMouse
Entrez

9221

n/a

Ensembl

ENSG00000166197

n/a

UniProt

Q14978

n/a

RefSeq (mRNA)

NM_001284388
NM_001284389
NM_004741

n/a

RefSeq (protein)

NP_001271317
NP_001271318
NP_004732

n/a

Location (UCSC)Chr 10: 102.15 – 102.16 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Interactions edit

Nucleolar phosphoprotein p130 has been shown to interact with coilin[6] and CEBPB.[7]

References edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000166197 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Pai CY, Chen HK, Sheu HL, Yeh NH (Oct 1995). "Cell-cycle-dependent alterations of a highly phosphorylated nucleolar protein p130 are associated with nucleologenesis". J Cell Sci. 108. ( Pt 5) (5): 1911–20. doi:10.1242/jcs.108.5.1911. PMID 7657714.
  4. ^ Chen HK, Pai CY, Huang JY, Yeh NH (Jan 2000). "Human Nopp140, which interacts with RNA polymerase I: implications for rRNA gene transcription and nucleolar structural organization". Mol Cell Biol. 19 (12): 8536–46. doi:10.1128/MCB.19.12.8536. PMC 84972. PMID 10567578.
  5. ^ "Entrez Gene: NOLC1 nucleolar and coiled-body phosphoprotein 1".
  6. ^ Isaac, C; Yang Y; Meier U T (Jul 1998). "Nopp140 functions as a molecular link between the nucleolus and the coiled bodies". J. Cell Biol. 142 (2): 319–29. doi:10.1083/jcb.142.2.319. ISSN 0021-9525. PMC 2133063. PMID 9679133.
  7. ^ Miau, L H; Chang C J; Shen B J; Tsai W H; Lee S C (Apr 1998). "Identification of heterogeneous nuclear ribonucleoprotein K (hnRNP K) as a repressor of C/EBPbeta-mediated gene activation". J. Biol. Chem. 273 (17): 10784–91. doi:10.1074/jbc.273.17.10784. ISSN 0021-9258. PMID 9553145.

Further reading edit

  • Nomura N, Miyajima N, Sazuka T, et al. (1995). "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1". DNA Res. 1 (1): 27–35. doi:10.1093/dnares/1.1.27. PMID 7584026.
  • Nomura N, Miyajima N, Sazuka T, et al. (1995). "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement)". DNA Res. 1 (1): 47–56. doi:10.1093/dnares/1.1.47. PMID 7584028.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Pai CY, Yeh NH (1996). "Cell proliferation-dependent expression of two isoforms of the nucleolar phosphoprotein p130". Biochem. Biophys. Res. Commun. 221 (3): 581–7. doi:10.1006/bbrc.1996.0639. PMID 8630004.
  • Miau LH, Chang CJ, Tsai WH, Lee SC (1997). "Identification and characterization of a nucleolar phosphoprotein, Nopp140, as a transcription factor". Mol. Cell. Biol. 17 (1): 230–9. doi:10.1128/MCB.17.1.230. PMC 231747. PMID 8972203.
  • Li D, Meier UT, Dobrowolska G, Krebs EG (1997). "Specific interaction between casein kinase 2 and the nucleolar protein Nopp140". J. Biol. Chem. 272 (6): 3773–9. doi:10.1074/jbc.272.6.3773. PMID 9013635.
  • Chen HK, Yeh NH (1997). "The nucleolar phosphoprotein P130 is a GTPase/ATPase with intrinsic property to form large complexes triggered by F- and Mg2+". Biochem. Biophys. Res. Commun. 230 (2): 370–5. doi:10.1006/bbrc.1996.5966. PMID 9016786.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Miau LH, Chang CJ, Shen BJ, et al. (1998). "Identification of heterogeneous nuclear ribonucleoprotein K (hnRNP K) as a repressor of C/EBPbeta-mediated gene activation". J. Biol. Chem. 273 (17): 10784–91. doi:10.1074/jbc.273.17.10784. PMID 9553145.
  • Isaac C, Yang Y, Meier UT (1998). "Nopp140 functions as a molecular link between the nucleolus and the coiled bodies". J. Cell Biol. 142 (2): 319–29. doi:10.1083/jcb.142.2.319. PMC 2133063. PMID 9679133.
  • Blanchette P, Gilchrist CA, Baker RT, Gray DA (2001). "Association of UNP, a ubiquitin-specific protease, with the pocket proteins pRb, p107 and p130". Oncogene. 20 (39): 5533–7. doi:10.1038/sj.onc.1204823. PMID 11571651.
  • Chiu CM, Tsay YG, Chang CJ, Lee SC (2002). "Nopp140 is a mediator of the protein kinase A signaling pathway that activates the acute phase response alpha1-acid glycoprotein gene". J. Biol. Chem. 277 (42): 39102–11. doi:10.1074/jbc.M205915200. PMID 12167624.
  • Wang C, Query CC, Meier UT (2003). "Immunopurified small nucleolar ribonucleoprotein particles pseudouridylate rRNA independently of their association with phosphorylated Nopp140". Mol. Cell. Biol. 22 (24): 8457–66. doi:10.1128/MCB.22.24.8457-8466.2002. PMC 139890. PMID 12446766.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry". Anal. Chem. 76 (10): 2763–72. doi:10.1021/ac035352d. PMID 15144186.
  • Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197. S2CID 27764390.
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
 

This article on a gene on human chromosome 10 is a stub. You can help Wikipedia by expanding it.

May 01, 2024
nucleolar, phosphoprotein, p130, protein, that, humans, encoded, nolc1, gene, nolc1identifiersaliasesnolc1, nopp130, nopp140, ns5atp13, p130, nucleolar, coiled, body, phosphoprotein, srp40external, idsomim, 602394, homologene, 68818, genecards, nolc1gene, loca. Nucleolar phosphoprotein p130 is a protein that in humans is encoded by the NOLC1 gene 3 4 5 NOLC1IdentifiersAliasesNOLC1 NOPP130 NOPP140 NS5ATP13 P130 Nucleolar phosphoprotein p130 nucleolar and coiled body phosphoprotein 1 Srp40External IDsOMIM 602394 HomoloGene 68818 GeneCards NOLC1Gene location Human Chr Chromosome 10 human 1 Band10q24 32Start102 152 176 bp 1 End102 163 871 bp 1 RNA expression patternBgeeHumanMouse ortholog Top expressed inmiddle temporal gyrusBrodmann area 23germinal epitheliumparietal pleuraendothelial cellpancreatic epithelial cellvisceral pleuraspermtibiaamniotic fluidn aMore reference expression dataBioGPSMore reference expression dataGene ontologyMolecular functionnucleotide binding GTP binding protein binding ATP binding RNA binding RNA polymerase I core binding protein heterodimerization activity DNA binding DNA binding transcription factor activity transcription factor binding nuclear localization sequence binding protein domain specific binding box C D RNA binding box H ACA snoRNA binding box C D snoRNP complex binding box H ACA snoRNP complex bindingCellular componentcytoplasm Cajal body nucleus nucleoplasm nucleolus fibrillar center box C D RNP complex box H ACA snoRNP complexBiological processrRNA processing cell cycle nucleolus organization regulation of translation neural crest formation neural crest cell development mitotic cell cycle response to osmotic stress positive regulation of cell population proliferation box H ACA RNA metabolic process regulation of protein import into nucleus positive regulation of transcription DNA templatedSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez9221n aEnsemblENSG00000166197n aUniProtQ14978n aRefSeq mRNA NM 001284388NM 001284389NM 004741n aRefSeq protein NP 001271317NP 001271318NP 004732n aLocation UCSC Chr 10 102 15 102 16 Mbn aPubMed search 2 n aWikidataView Edit HumanInteractions editNucleolar phosphoprotein p130 has been shown to interact with coilin 6 and CEBPB 7 References edit a b c GRCh38 Ensembl release 89 ENSG00000166197 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Pai CY Chen HK Sheu HL Yeh NH Oct 1995 Cell cycle dependent alterations of a highly phosphorylated nucleolar protein p130 are associated with nucleologenesis J Cell Sci 108 Pt 5 5 1911 20 doi 10 1242 jcs 108 5 1911 PMID 7657714 Chen HK Pai CY Huang JY Yeh NH Jan 2000 Human Nopp140 which interacts with RNA polymerase I implications for rRNA gene transcription and nucleolar structural organization Mol Cell Biol 19 12 8536 46 doi 10 1128 MCB 19 12 8536 PMC 84972 PMID 10567578 Entrez Gene NOLC1 nucleolar and coiled body phosphoprotein 1 Isaac C Yang Y Meier U T Jul 1998 Nopp140 functions as a molecular link between the nucleolus and the coiled bodies J Cell Biol 142 2 319 29 doi 10 1083 jcb 142 2 319 ISSN 0021 9525 PMC 2133063 PMID 9679133 Miau L H Chang C J Shen B J Tsai W H Lee S C Apr 1998 Identification of heterogeneous nuclear ribonucleoprotein K hnRNP K as a repressor of C EBPbeta mediated gene activation J Biol Chem 273 17 10784 91 doi 10 1074 jbc 273 17 10784 ISSN 0021 9258 PMID 9553145 Further reading editNomura N Miyajima N Sazuka T et al 1995 Prediction of the coding sequences of unidentified human genes I The coding sequences of 40 new genes KIAA0001 KIAA0040 deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG 1 DNA Res 1 1 27 35 doi 10 1093 dnares 1 1 27 PMID 7584026 Nomura N Miyajima N Sazuka T et al 1995 Prediction of the coding sequences of unidentified human genes I The coding sequences of 40 new genes KIAA0001 KIAA0040 deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG 1 supplement DNA Res 1 1 47 56 doi 10 1093 dnares 1 1 47 PMID 7584028 Maruyama K Sugano S 1994 Oligo capping a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides Gene 138 1 2 171 4 doi 10 1016 0378 1119 94 90802 8 PMID 8125298 Pai CY Yeh NH 1996 Cell proliferation dependent expression of two isoforms of the nucleolar phosphoprotein p130 Biochem Biophys Res Commun 221 3 581 7 doi 10 1006 bbrc 1996 0639 PMID 8630004 Miau LH Chang CJ Tsai WH Lee SC 1997 Identification and characterization of a nucleolar phosphoprotein Nopp140 as a transcription factor Mol Cell Biol 17 1 230 9 doi 10 1128 MCB 17 1 230 PMC 231747 PMID 8972203 Li D Meier UT Dobrowolska G Krebs EG 1997 Specific interaction between casein kinase 2 and the nucleolar protein Nopp140 J Biol Chem 272 6 3773 9 doi 10 1074 jbc 272 6 3773 PMID 9013635 Chen HK Yeh NH 1997 The nucleolar phosphoprotein P130 is a GTPase ATPase with intrinsic property to form large complexes triggered by F and Mg2 Biochem Biophys Res Commun 230 2 370 5 doi 10 1006 bbrc 1996 5966 PMID 9016786 Suzuki Y Yoshitomo Nakagawa K Maruyama K et al 1997 Construction and characterization of a full length enriched and a 5 end enriched cDNA library Gene 200 1 2 149 56 doi 10 1016 S0378 1119 97 00411 3 PMID 9373149 Miau LH Chang CJ Shen BJ et al 1998 Identification of heterogeneous nuclear ribonucleoprotein K hnRNP K as a repressor of C EBPbeta mediated gene activation J Biol Chem 273 17 10784 91 doi 10 1074 jbc 273 17 10784 PMID 9553145 Isaac C Yang Y Meier UT 1998 Nopp140 functions as a molecular link between the nucleolus and the coiled bodies J Cell Biol 142 2 319 29 doi 10 1083 jcb 142 2 319 PMC 2133063 PMID 9679133 Blanchette P Gilchrist CA Baker RT Gray DA 2001 Association of UNP a ubiquitin specific protease with the pocket proteins pRb p107 and p130 Oncogene 20 39 5533 7 doi 10 1038 sj onc 1204823 PMID 11571651 Chiu CM Tsay YG Chang CJ Lee SC 2002 Nopp140 is a mediator of the protein kinase A signaling pathway that activates the acute phase response alpha1 acid glycoprotein gene J Biol Chem 277 42 39102 11 doi 10 1074 jbc M205915200 PMID 12167624 Wang C Query CC Meier UT 2003 Immunopurified small nucleolar ribonucleoprotein particles pseudouridylate rRNA independently of their association with phosphorylated Nopp140 Mol Cell Biol 22 24 8457 66 doi 10 1128 MCB 22 24 8457 8466 2002 PMC 139890 PMID 12446766 Strausberg RL Feingold EA Grouse LH et al 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 Bibcode 2002PNAS 9916899M doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Ota T Suzuki Y Nishikawa T et al 2004 Complete sequencing and characterization of 21 243 full length human cDNAs Nat Genet 36 1 40 5 doi 10 1038 ng1285 PMID 14702039 Brill LM Salomon AR Ficarro SB et al 2004 Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry Anal Chem 76 10 2763 72 doi 10 1021 ac035352d PMID 15144186 Brandenberger R Wei H Zhang S et al 2005 Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation Nat Biotechnol 22 6 707 16 doi 10 1038 nbt971 PMID 15146197 S2CID 27764390 Beausoleil SA Jedrychowski M Schwartz D et al 2004 Large scale characterization of HeLa cell nuclear phosphoproteins Proc Natl Acad Sci U S A 101 33 12130 5 Bibcode 2004PNAS 10112130B doi 10 1073 pnas 0404720101 PMC 514446 PMID 15302935 nbsp This article on a gene on human chromosome 10 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Nucleolar phosphoprotein p130 amp oldid 1116601342, wikipedia, wiki, book, books, library,

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