Neuropixels probes (or "Neuropixels") are electrodes developed in 2017 to record the activity of hundreds of neurons in the brain. The probes are based on CMOS technology and have 1,000 recording sites arranged in two rows on a thin, 1-cm long shank.[1][2]
The probes are used in hundreds of neuroscience laboratories including the International Brain Laboratory, to record brain activity mostly in mice and rats. By revealing the activity of vast numbers of neurons, Neuropixels probes are allowing new approaches[3] to the study of brain processes such as sensory processing, decision making,[4] internal state,[5] and emotions[6] and to create brain-machine interfaces.[7][8]
The probes were announced in 2017.[9] They are designed and fabricated by imec, an electronics research center in Belgium. In 2022, Neuropixels probes were inserted in human patients.[10]
Referencesedit
^"How to make sense of the brain's billions of neurons | Wellcome". wellcome.ac.uk. 31 October 2018. Retrieved 2020-08-25.
^"A new nerve-cell monitor will help those studying brains". The Economist. ISSN 0013-0613. Retrieved 2022-11-01.
^Hernandez, Daniela (2018-06-15). "The Quest to Decode the Brain". Wall Street Journal. ISSN 0099-9660. Retrieved 2020-08-25.
^Steinmetz, Nicholas A.; Zatka-Haas, Peter; Carandini, Matteo; Harris, Kenneth D. (December 2019). "Distributed coding of choice, action and engagement across the mouse brain". Nature. 576 (7786): 266–273. doi:10.1038/s41586-019-1787-x. ISSN 1476-4687. PMC6913580. PMID 31776518.
^Allen, William E.; Chen, Michael Z.; Pichamoorthy, Nandini; Tien, Rebecca H.; Pachitariu, Marius; Luo, Liqun; Deisseroth, Karl (2019-04-19). "Thirst regulates motivated behavior through modulation of brainwide neural population dynamics". Science. 364 (6437): 253. Bibcode:2019Sci...364..253A. doi:10.1126/science.aav3932. ISSN 0036-8075. PMC6711472. PMID 30948440.
^Abbott, Alison (2020-08-11). "Inside the mind of an animal". Nature. 584 (7820): 182–185. Bibcode:2020Natur.584..182A. doi:10.1038/d41586-020-02337-x. PMID 32782378.
^"How brains and machines can be made to work together". The Economist. ISSN 0013-0613. Retrieved 2020-08-25.
^Markoff, John (2019-07-16). "Elon Musk's Neuralink Wants 'Sewing Machine-Like' Robots to Wire Brains to the Internet". The New York Times. ISSN 0362-4331. Retrieved 2020-08-25.
^Jun, James J.; Steinmetz, Nicholas A.; Siegle, Joshua H.; Denman, Daniel J.; Bauza, Marius; Barbarits, Brian; Lee, Albert K.; Anastassiou, Costas A.; Andrei, Alexandru; Aydın, Çağatay; Barbic, Mladen (2017-11-08). "Fully Integrated Silicon Probes for High-Density Recording of Neural Activity". Nature. 551 (7679): 232–236. Bibcode:2017Natur.551..232J. doi:10.1038/nature24636. ISSN 0028-0836. PMC5955206. PMID 29120427.
^Paulk, Angelique C.; Kfir, Yoav; Khanna, Arjun R.; Mustroph, Martina L.; Trautmann, Eric M.; Soper, Dan J.; Stavisky, Sergey D.; Welkenhuysen, Marleen; Dutta, Barundeb; Shenoy, Krishna V.; Hochberg, Leigh R.; Richardson, R. Mark; Williams, Ziv M.; Cash, Sydney S. (February 2022). "Large-scale neural recordings with single neuron resolution using Neuropixels probes in human cortex". Nature Neuroscience. 25 (2): 252–263. doi:10.1038/s41593-021-00997-0. ISSN 1546-1726. PMID 35102333. S2CID 246442929.
External linksedit
UCL Neuropixels page
neuropixels.org
SpikeGLX: Neuropixels acquisition software
Open Ephys GUI: Neuropixels acquisition software
Neuropixels slack channel
April 12, 2024
neuropixels, probes, electrodes, developed, 2017, record, activity, hundreds, neurons, brain, probes, based, cmos, technology, have, recording, sites, arranged, rows, thin, long, shank, probes, used, hundreds, neuroscience, laboratories, including, internation. Neuropixels probes or Neuropixels are electrodes developed in 2017 to record the activity of hundreds of neurons in the brain The probes are based on CMOS technology and have 1 000 recording sites arranged in two rows on a thin 1 cm long shank 1 2 The probes are used in hundreds of neuroscience laboratories including the International Brain Laboratory to record brain activity mostly in mice and rats By revealing the activity of vast numbers of neurons Neuropixels probes are allowing new approaches 3 to the study of brain processes such as sensory processing decision making 4 internal state 5 and emotions 6 and to create brain machine interfaces 7 8 The probes were announced in 2017 9 They are designed and fabricated by imec an electronics research center in Belgium In 2022 Neuropixels probes were inserted in human patients 10 References edit How to make sense of the brain s billions of neurons Wellcome wellcome ac uk 31 October 2018 Retrieved 2020 08 25 A new nerve cell monitor will help those studying brains The Economist ISSN 0013 0613 Retrieved 2022 11 01 Hernandez Daniela 2018 06 15 The Quest to Decode the Brain Wall Street Journal ISSN 0099 9660 Retrieved 2020 08 25 Steinmetz Nicholas A Zatka Haas Peter Carandini Matteo Harris Kenneth D December 2019 Distributed coding of choice action and engagement across the mouse brain Nature 576 7786 266 273 doi 10 1038 s41586 019 1787 x ISSN 1476 4687 PMC 6913580 PMID 31776518 Allen William E Chen Michael Z Pichamoorthy Nandini Tien Rebecca H Pachitariu Marius Luo Liqun Deisseroth Karl 2019 04 19 Thirst regulates motivated behavior through modulation of brainwide neural population dynamics Science 364 6437 253 Bibcode 2019Sci 364 253A doi 10 1126 science aav3932 ISSN 0036 8075 PMC 6711472 PMID 30948440 Abbott Alison 2020 08 11 Inside the mind of an animal Nature 584 7820 182 185 Bibcode 2020Natur 584 182A doi 10 1038 d41586 020 02337 x PMID 32782378 How brains and machines can be made to work together The Economist ISSN 0013 0613 Retrieved 2020 08 25 Markoff John 2019 07 16 Elon Musk s Neuralink Wants Sewing Machine Like Robots to Wire Brains to the Internet The New York Times ISSN 0362 4331 Retrieved 2020 08 25 Jun James J Steinmetz Nicholas A Siegle Joshua H Denman Daniel J Bauza Marius Barbarits Brian Lee Albert K Anastassiou Costas A Andrei Alexandru Aydin Cagatay Barbic Mladen 2017 11 08 Fully Integrated Silicon Probes for High Density Recording of Neural Activity Nature 551 7679 232 236 Bibcode 2017Natur 551 232J doi 10 1038 nature24636 ISSN 0028 0836 PMC 5955206 PMID 29120427 Paulk Angelique C Kfir Yoav Khanna Arjun R Mustroph Martina L Trautmann Eric M Soper Dan J Stavisky Sergey D Welkenhuysen Marleen Dutta Barundeb Shenoy Krishna V Hochberg Leigh R Richardson R Mark Williams Ziv M Cash Sydney S February 2022 Large scale neural recordings with single neuron resolution using Neuropixels probes in human cortex Nature Neuroscience 25 2 252 263 doi 10 1038 s41593 021 00997 0 ISSN 1546 1726 PMID 35102333 S2CID 246442929 External links editUCL Neuropixels page neuropixels org SpikeGLX Neuropixels acquisition software Open Ephys GUI Neuropixels acquisition software Neuropixels slack channel Retrieved from https en wikipedia org w index php title Neuropixels amp oldid 1204692200, wikipedia, wiki, book, books, library,
