A narrow-spectrum antibiotic is an antibiotic that is only able to kill or inhibit limited species of bacteria.[1] Examples of narrow-spectrum antibiotics include fidaxomicin and sarecycline.
Narrow-spectrum antibiotic allow to kill or inhibit only those bacteria species that are unwanted (i.e. causing disease). As such, it leaves most of the beneficial bacteria unaffected, hence minimizing the collateral damage on the microbiota.[2][3]
Often, the exact species of bacteria causing the illness is unknown, in which case narrow-spectrum antibiotics can't be used, and broad-spectrum antibiotics are used instead. To know the exact species of bacteria causing the illness, clinical specimens need to be taken for antimicrobial susceptibility testing in a clinical microbiology laboratory.[citation needed]
narrow, spectrum, antibiotic, narrow, spectrum, antibiotic, antibiotic, that, only, able, kill, inhibit, limited, species, bacteria, examples, narrow, spectrum, antibiotics, include, fidaxomicin, sarecycline, contents, advantages, disadvantages, also, referenc. A narrow spectrum antibiotic is an antibiotic that is only able to kill or inhibit limited species of bacteria 1 Examples of narrow spectrum antibiotics include fidaxomicin and sarecycline Contents 1 Advantages 2 Disadvantages 3 See also 4 References 5 Further readingAdvantages editNarrow spectrum antibiotic allow to kill or inhibit only those bacteria species that are unwanted i e causing disease As such it leaves most of the beneficial bacteria unaffected hence minimizing the collateral damage on the microbiota 2 3 Low propensity for bacterial resistance development 4 Disadvantages editOften the exact species of bacteria causing the illness is unknown in which case narrow spectrum antibiotics can t be used and broad spectrum antibiotics are used instead To know the exact species of bacteria causing the illness clinical specimens need to be taken for antimicrobial susceptibility testing in a clinical microbiology laboratory citation needed See also editAntimicrobial spectrum Broad spectrum antibioticsReferences edit Hopkins SJ 1997 Drugs and Pharmacology for Nurses 12th ed Churchill Livingstone ISBN 978 0 443 05249 1 Blaser M August 2011 Antibiotic overuse Stop the killing of beneficial bacteria Nature 476 7361 393 4 Bibcode 2011Natur 476 393B doi 10 1038 476393a PMID 21866137 S2CID 205066874 Keener AB 9 May 2016 Narrow Spectrum Antibiotic Could Spare the Microbiome The Scientist Magazine Retrieved 2020 06 07 Melander RJ Zurawski DV Melander C 2018 Narrow Spectrum Antibacterial Agents MedChemComm 9 1 12 21 doi 10 1039 c7md00528h PMC 5839511 PMID 29527285 Further reading editRepurposing CRISPR Cas systems as DNA based smart antimicrobials nbsp This systemic antibiotic related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Narrow spectrum antibiotic amp oldid 1178076738, wikipedia, wiki, book, books, library,
