This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is unspecific diphosphate phosphohydrolase. Other names in common use include nucleoside triphosphate phosphohydrolase, nucleoside-5-triphosphate phosphohydrolase, and nucleoside 5-triphosphatase. This enzyme participates in purine metabolism and thiamine metabolism.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2I3B.
References
Brightwell R, Tappel AL (1968). "Lysosomal acid pyrophosphatase and acid phosphatase". Arch. Biochem. Biophys. 124 (1): 333–43. doi:10.1016/0003-9861(68)90335-4. PMID 5661608.
LEWIS M, WEISSMAN S (1965). "Properties of a soluble nucleoside triphosphatase activity in mammalian liver". Arch. Biochem. Biophys. 109 (3): 490–8. doi:10.1016/0003-9861(65)90393-0. PMID 14320490.
Matsushita S, Raacke ID (1968). "Purification of nucleoside triphosphatases from pea seedling ribosomes". Biochim. Biophys. Acta. 166 (3): 707–10. doi:10.1016/0005-2787(68)90380-8. PMID 4301913.
nucleoside, triphosphatase, enzymology, nucleoside, triphosphatase, ntpase, enzyme, that, catalyzes, chemical, reactionnucleoside, triphosphataseidentifiersec, 15cas, 9075, 8databasesintenzintenz, viewbrendabrenda, entryexpasynicezyme, viewkeggkegg, entrymetac. In enzymology a nucleoside triphosphatase NTPase EC 3 6 1 15 is an enzyme that catalyzes the chemical reactionnucleoside triphosphataseIdentifiersEC no 3 6 1 15CAS no 9075 51 8DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumGene OntologyAmiGO QuickGOSearchPMCarticlesPubMedarticlesNCBIproteins NTP H2O displaystyle rightleftharpoons NDP phosphateThus the two substrates of this enzyme are NTP and H2O whereas its two products are NDP and phosphate This enzyme belongs to the family of hydrolases specifically those acting on acid anhydrides in phosphorus containing anhydrides The systematic name of this enzyme class is unspecific diphosphate phosphohydrolase Other names in common use include nucleoside triphosphate phosphohydrolase nucleoside 5 triphosphate phosphohydrolase and nucleoside 5 triphosphatase This enzyme participates in purine metabolism and thiamine metabolism Structural studies EditAs of late 2007 only one structure has been solved for this class of enzymes with the PDB accession code 2I3B References EditBrightwell R Tappel AL 1968 Lysosomal acid pyrophosphatase and acid phosphatase Arch Biochem Biophys 124 1 333 43 doi 10 1016 0003 9861 68 90335 4 PMID 5661608 LEWIS M WEISSMAN S 1965 Properties of a soluble nucleoside triphosphatase activity in mammalian liver Arch Biochem Biophys 109 3 490 8 doi 10 1016 0003 9861 65 90393 0 PMID 14320490 Matsushita S Raacke ID 1968 Purification of nucleoside triphosphatases from pea seedling ribosomes Biochim Biophys Acta 166 3 707 10 doi 10 1016 0005 2787 68 90380 8 PMID 4301913 Portal Biology This EC 3 6 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Nucleoside triphosphatase amp oldid 1085483282, wikipedia, wiki, book, books, library,
