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N-methyl-2-oxoglutaramate hydrolase

In enzymology, a N-methyl-2-oxoglutaramate hydrolase (EC 3.5.1.36) is an enzyme that catalyzes the chemical reaction

N-methyl-2-oxoglutaramate hydrolase
Identifiers
EC no.3.5.1.36
CAS no.9073-53-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
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NCBIproteins
N-methyl-2-oxoglutaramate + H2O 2-oxoglutarate + methylamine

Thus, the two substrates of this enzyme are N-methyl-2-oxoglutaramate and H2O, whereas its two products are 2-oxoglutarate and methylamine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-methyl-2-oxoglutaramate methylamidohydrolase. This enzyme is also called 5-hydroxy-N-methylpyroglutamate synthase.

References edit

  • Hersh LB (1970). "5-hydroxy-N-methylpyroglutamate synthetase. Purification and mechanism of action". J. Biol. Chem. 245 (14): 3526–35. PMID 5470822.
  • Hersh LB, Tsai L, Stadtman ER (1969). "The enzymatic synthesis of 5-hydroxy-N-methylpyroglutamic acid". J. Biol. Chem. 244 (17): 4677–83. PMID 5808511.


methyl, oxoglutaramate, hydrolase, enzymology, enzyme, that, catalyzes, chemical, reactionidentifiersec, 36cas, 9073, 4databasesintenzintenz, viewbrendabrenda, entryexpasynicezyme, viewkeggkegg, entrymetacycmetabolic, pathwaypriamprofilepdb, structuresrcsb, pd. In enzymology a N methyl 2 oxoglutaramate hydrolase EC 3 5 1 36 is an enzyme that catalyzes the chemical reactionN methyl 2 oxoglutaramate hydrolaseIdentifiersEC no 3 5 1 36CAS no 9073 53 4DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumGene OntologyAmiGO QuickGOSearchPMCarticlesPubMedarticlesNCBIproteins N methyl 2 oxoglutaramate H2O displaystyle rightleftharpoons 2 oxoglutarate methylamineThus the two substrates of this enzyme are N methyl 2 oxoglutaramate and H2O whereas its two products are 2 oxoglutarate and methylamine This enzyme belongs to the family of hydrolases those acting on carbon nitrogen bonds other than peptide bonds specifically in linear amides The systematic name of this enzyme class is N methyl 2 oxoglutaramate methylamidohydrolase This enzyme is also called 5 hydroxy N methylpyroglutamate synthase References editHersh LB 1970 5 hydroxy N methylpyroglutamate synthetase Purification and mechanism of action J Biol Chem 245 14 3526 35 PMID 5470822 Hersh LB Tsai L Stadtman ER 1969 The enzymatic synthesis of 5 hydroxy N methylpyroglutamic acid J Biol Chem 244 17 4677 83 PMID 5808511 Portal nbsp Biology This EC 3 5 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title N methyl 2 oxoglutaramate hydrolase amp oldid 1172354658, wikipedia, wiki, book, books, library,

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