This article is about bone marrow cells and tissue. For spinal cord tissue, see spinal cord.
Myeloid tissue, in the bone marrow sense of the word myeloid (myelo- + -oid), is tissue of bone marrow, of bone marrow cell lineage, or resembling bone marrow, and myelogenous tissue (myelo- + -genous) is any tissue of, or arising from, bone marrow; in these senses the terms are usually used synonymously, as for example with chronic myeloid/myelogenous leukemia.
Diagram showing the development of different blood cells from haematopoietic stem cell to mature cellsComprehensive diagram that shows the development of different blood cells from haematopoietic stem cell to mature cells in both myeloid and lymphoid lineages.
In hematopoiesis, myeloid cells, or myelogenous cells are blood cells that arise from a progenitor cell for granulocytes, monocytes, erythrocytes, or platelets[1][2] (the common myeloid progenitor, that is, CMP or CFU-GEMM), or in a narrower sense also often used, specifically from the lineage of the myeloblast (the myelocytes, monocytes, and their daughter types). Thus, although all blood cells, even lymphocytes, are normally born in the bone marrow in adults, myeloid cells in the narrowest sense of the term can be distinguished from lymphoid cells, that is, lymphocytes, which come from common lymphoid progenitor cells that give rise to B cells and T cells.[2] Those cells' differentiation (that is, lymphopoiesis) is not complete until they migrate to lymphatic organs such as the spleen and thymus for programming by antigen challenge. Thus, among leukocytes, the term myeloid is associated with the innate immune system, in contrast to lymphoid, which is associated with the adaptive immune system. Similarly, myelogenous usually refers to nonlymphocytic white blood cells,[3] and erythroid can often be used to distinguish "erythrocyte-related" from that sense of myeloid and from lymphoid.[4]
The word myelopoiesis has several senses in a way that parallels those of myeloid, and myelopoiesis in the narrower sense is the regulated formation specifically of myeloid leukocytes (myelocytes), allowing that sense of myelopoiesis to be contradistinguished from erythropoiesis and lymphopoiesis (even though all blood cells are normally produced in the marrow in adults).
There is one other sense of myeloid that means "pertaining to the spinal cord", but it is much less commonly used. Myeloid should not be confused with myelin, referring to an insulating layer covering the axons of many neurons.
^ abOrkin SH, Zon LI (2008). "Hematopoiesis: an evolving paradigm for stem cell biology". Cell. 132 (4): 631–644. doi:10.1016/j.cell.2008.01.025. PMC2628169. PMID 18295580.
^"Definition of Myelogenous". MedicineNet. August 28, 2013. Retrieved 2015-09-10.
^Yuan J, Nguyen CK, Liu X, Kanellopoulou C, Muljo SA (2012). "Lin28b reprograms adult bone marrow hematopoietic progenitors to mediate fetal-like lymphopoiesis". Science. 335 (6073): 1195–1200. doi:10.1126/science.1216557. PMC3471381. PMID 22345399.
^Semester 4 medical lectures at Uppsala University 2008 by Leif Jansson
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November 29, 2023
myeloid, tissue, this, article, about, bone, marrow, cells, tissue, spinal, cord, tissue, spinal, cord, bone, marrow, sense, word, myeloid, myelo, tissue, bone, marrow, bone, marrow, cell, lineage, resembling, bone, marrow, myelogenous, tissue, myelo, genous, . This article is about bone marrow cells and tissue For spinal cord tissue see spinal cord Myeloid tissue in the bone marrow sense of the word myeloid myelo oid is tissue of bone marrow of bone marrow cell lineage or resembling bone marrow and myelogenous tissue myelo genous is any tissue of or arising from bone marrow in these senses the terms are usually used synonymously as for example with chronic myeloid myelogenous leukemia Diagram showing the development of different blood cells from haematopoietic stem cell to mature cellsComprehensive diagram that shows the development of different blood cells from haematopoietic stem cell to mature cells in both myeloid and lymphoid lineages In hematopoiesis myeloid cells or myelogenous cells are blood cells that arise from a progenitor cell for granulocytes monocytes erythrocytes or platelets 1 2 the common myeloid progenitor that is CMP or CFU GEMM or in a narrower sense also often used specifically from the lineage of the myeloblast the myelocytes monocytes and their daughter types Thus although all blood cells even lymphocytes are normally born in the bone marrow in adults myeloid cells in the narrowest sense of the term can be distinguished from lymphoid cells that is lymphocytes which come from common lymphoid progenitor cells that give rise to B cells and T cells 2 Those cells differentiation that is lymphopoiesis is not complete until they migrate to lymphatic organs such as the spleen and thymus for programming by antigen challenge Thus among leukocytes the term myeloid is associated with the innate immune system in contrast to lymphoid which is associated with the adaptive immune system Similarly myelogenous usually refers to nonlymphocytic white blood cells 3 and erythroid can often be used to distinguish erythrocyte related from that sense of myeloid and from lymphoid 4 The word myelopoiesis has several senses in a way that parallels those of myeloid and myelopoiesis in the narrower sense is the regulated formation specifically of myeloid leukocytes myelocytes allowing that sense of myelopoiesis to be contradistinguished from erythropoiesis and lymphopoiesis even though all blood cells are normally produced in the marrow in adults Myeloid neoplasms always concern bone marrow cell lineage and are related to hematopoietic cells Myeloid tissue can also be present in the liver and spleen 5 in fetuses and sometimes even in adults as well which leads to extramedullary hematopoiesis There is one other sense of myeloid that means pertaining to the spinal cord but it is much less commonly used Myeloid should not be confused with myelin referring to an insulating layer covering the axons of many neurons See also editAcute myeloid leukemia Chronic myelogenous leukemia Hematopoietic stem cellReferences edit Kawamoto H Minato N 2004 Myeloid cells The International Journal of Biochemistry amp Cell Biology 36 8 1374 1379 doi 10 1016 j biocel 2004 01 020 PMID 15147715 a b Orkin SH Zon LI 2008 Hematopoiesis an evolving paradigm for stem cell biology Cell 132 4 631 644 doi 10 1016 j cell 2008 01 025 PMC 2628169 PMID 18295580 Definition of Myelogenous MedicineNet August 28 2013 Retrieved 2015 09 10 Yuan J Nguyen CK Liu X Kanellopoulou C Muljo SA 2012 Lin28b reprograms adult bone marrow hematopoietic progenitors to mediate fetal like lymphopoiesis Science 335 6073 1195 1200 doi 10 1126 science 1216557 PMC 3471381 PMID 22345399 Semester 4 medical lectures at Uppsala University 2008 by Leif JanssonExternal links edit nbsp Wikimedia Commons has media related to Myeloid cells nbsp Look up myeloid in Wiktionary the free dictionary Retrieved from https en wikipedia org w index php title Myeloid tissue amp oldid 1172475156, wikipedia, wiki, book, books, library,
