Mycoplasma hyorhinis is a species of bacteria in the Mycoplasmataceae family. It is often found as a commensal in the respiratory tract of pigs, and rarely in the skin of humans. M. hyorhinis is thought to facilitate and exacerbate the development of diseases such as porcine enzootic pneumonia and porcine reproductive and respiratory syndrome (PRRS). Rarely, it may cause mycoplasma arthritis, mycoplasmal polyserositis or mycoplasma septicaemia in piglets without the involvement of other bacteria. This presents as polyarthritis or polyserositis.
A variety of clinical signs are seen in piglets less than 10-weeks old.
Lameness, polyserositis and joint swelling are the most common symptoms. A foul-smelling discharge from the ears can occur secondary to otitis. Less specific signs include poor coat quality, pyrexia, cardiovascular, gastrointestinal, neurological and respiratory signs.
There is some evidence implicating M. hyorhinis in the pathogenesis of scleroderma, a chronic systemic disease of humans. One study isolated the bacteria from scleroderma patients.[2] Another study found that injecting M. hyorhinis into mice induces a scleroderma-like autoimmune disease.[3] However, more research is needed to confirm or refute the link between M. hyorhinis and scleroderma.
^Shats I, Williams JG, Li X (2020). "Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway". Cell Metabolism. 31 (3): 564–5791. doi:10.1016/j.cmet.2020.02.001. PMC7194078. PMID 32130883.
^"New Strains of Mycoplasma Hyorhinis as Causative Agents for Autoimmune Disease".
mycoplasma, hyorhinis, this, article, needs, additional, citations, verification, please, help, improve, this, article, adding, citations, reliable, sources, unsourced, material, challenged, removed, find, sources, news, newspapers, books, scholar, jstor, sept. This article needs additional citations for verification Please help improve this article by adding citations to reliable sources Unsourced material may be challenged and removed Find sources Mycoplasma hyorhinis news newspapers books scholar JSTOR September 2022 Learn how and when to remove this template message Mycoplasma hyorhinis is a species of bacteria in the Mycoplasmataceae family It is often found as a commensal in the respiratory tract of pigs and rarely in the skin of humans M hyorhinis is thought to facilitate and exacerbate the development of diseases such as porcine enzootic pneumonia and porcine reproductive and respiratory syndrome PRRS Rarely it may cause mycoplasma arthritis mycoplasmal polyserositis or mycoplasma septicaemia in piglets without the involvement of other bacteria This presents as polyarthritis or polyserositis Mycoplasma hyorhinisScientific classificationDomain BacteriaPhylum MycoplasmatotaClass MollicutesOrder MycoplasmatalesFamily MycoplasmataceaeGenus MycoplasmaSpecies M hyorhinisBinomial nameMycoplasma hyorhinisSwitzer 1955 Approved Lists 1980 M hyorhinis can prevent cell death caused by nicotinamide phosphoribosyltransferase inhibitors 1 Contents 1 Clinical signs and diagnosis 2 Human pathogenicity 3 Treatment 4 See also 5 References 6 External linksClinical signs and diagnosis editA variety of clinical signs are seen in piglets less than 10 weeks old Lameness polyserositis and joint swelling are the most common symptoms A foul smelling discharge from the ears can occur secondary to otitis Less specific signs include poor coat quality pyrexia cardiovascular gastrointestinal neurological and respiratory signs Bacterial culture immunofluorescent antibody testing IFAT complement fixation test and haemagglutination can all be used to confirm the diagnosis Human pathogenicity editThere is some evidence implicating M hyorhinis in the pathogenesis of scleroderma a chronic systemic disease of humans One study isolated the bacteria from scleroderma patients 2 Another study found that injecting M hyorhinis into mice induces a scleroderma like autoimmune disease 3 However more research is needed to confirm or refute the link between M hyorhinis and scleroderma Treatment editAntibiotics are the treatment of choice See also editMycoplasmaReferences edit Shats I Williams JG Li X 2020 Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway Cell Metabolism 31 3 564 5791 doi 10 1016 j cmet 2020 02 001 PMC 7194078 PMID 32130883 New Strains of Mycoplasma Hyorhinis as Causative Agents for Autoimmune Disease Gavanescu I Pihan G Halilovic E Szomolanyi Tsuda E Welsh RM Doxsey S 2004 Mycoplasma infection induces a scleroderma like centrosome autoantibody response in mice Clin Exp Immunol 137 2 288 97 doi 10 1111 j 1365 2249 2004 02535 x PMC 1809115 PMID 15270845 Mycoplasma hyorhinis Wikivet Retrieved 13 September 2011 External links editType strain of Mycoplasma hyorhinis at BacDive the Bacterial Diversity Metadatabase nbsp This veterinary medicine related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Mycoplasma hyorhinis amp oldid 1111793395, wikipedia, wiki, book, books, library,
