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Mycocerosate synthase

In enzymology, a mycocerosate synthase (EC 2.3.1.111) is an enzyme that catalyzes the chemical reaction

mycocerosate synthase
Identifiers
EC no.2.3.1.111
CAS no.95229-19-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
acyl-CoA + n methylmalonyl-CoA + 2n NADPH + 2n H+ multi-methyl-branched acyl-CoA + n CoA + n CO2 + 2n NADP+

The 4 substrates of this enzyme are acyl-CoA, methylmalonyl-CoA, NADPH, and H+, whereas its 4 products are multi-methyl-branched acyl-CoA, CoA, CO2, and NADP+.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:methylmalonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing). This enzyme is also called mycocerosic acid synthase.

References edit

  • Rainwater DL, Kolattukudy PE (1985). "Fatty acid biosynthesis in Mycobacterium tuberculosis var. bovis Bacillus Calmette-Guerin. Purification and characterization of a novel fatty acid synthase, mycocerosic acid synthase, which elongates n-fatty acyl-CoA with methylmalonyl-CoA". J. Biol. Chem. 260 (1): 616–23. PMID 3880746.


mycocerosate, synthase, enzymology, mycocerosate, synthase, enzyme, that, catalyzes, chemical, reactionmycocerosate, synthaseidentifiersec, 111cas, 95229, 9databasesintenzintenz, viewbrendabrenda, entryexpasynicezyme, viewkeggkegg, entrymetacycmetabolic, pathw. In enzymology a mycocerosate synthase EC 2 3 1 111 is an enzyme that catalyzes the chemical reactionmycocerosate synthaseIdentifiersEC no 2 3 1 111CAS no 95229 19 9DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumGene OntologyAmiGO QuickGOSearchPMCarticlesPubMedarticlesNCBIproteins acyl CoA n methylmalonyl CoA 2n NADPH 2n H displaystyle rightleftharpoons multi methyl branched acyl CoA n CoA n CO2 2n NADP The 4 substrates of this enzyme are acyl CoA methylmalonyl CoA NADPH and H whereas its 4 products are multi methyl branched acyl CoA CoA CO2 and NADP This enzyme belongs to the family of transferases specifically those acyltransferases transferring groups other than aminoacyl groups The systematic name of this enzyme class is acyl CoA methylmalonyl CoA C acyltransferase decarboxylating oxoacyl and enoyl reducing This enzyme is also called mycocerosic acid synthase References editRainwater DL Kolattukudy PE 1985 Fatty acid biosynthesis in Mycobacterium tuberculosis var bovis Bacillus Calmette Guerin Purification and characterization of a novel fatty acid synthase mycocerosic acid synthase which elongates n fatty acyl CoA with methylmalonyl CoA J Biol Chem 260 1 616 23 PMID 3880746 Portal nbsp Biology This EC 2 3 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Mycocerosate synthase amp oldid 1172353969, wikipedia, wiki, book, books, library,

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