This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-N-acetyl-D-glucosamine:N-acetyl-alpha-D-muramyl(oyl-L-Ala-gamma- D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol beta-1,4-N-acetylglucosaminlytransferase. Another name in common use is MurG transferase. This enzyme participates in peptidoglycan biosynthesis.
Variant reactions producing modified cell walls include (not muturally exclusive):
Replacement of lysine residue with meso-diaminopimelate combined with adjacent residues through its L-centre, as it is in Gram-negative and some Gram-positive organisms.[1]
Use of mono-trans,octa-cis-decaprenyl instead of the conventional di-trans,octa-cis-undecaprenol moiety, as found in Mycobacterium.[2]
van Heijenoort J (October 2001). "Recent advances in the formation of the bacterial peptidoglycan monomer unit". Natural Product Reports. 18 (5): 503–19. doi:10.1039/a804532a. PMID 11699883.
undecaprenyldiphospho, muramoylpentapeptide, beta, acetylglucosaminyltransferase, enzymology, undecaprenyldiphospho, muramoylpentapeptide, beta, acetylglucosaminyltransferase, enzyme, that, catalyzes, chemical, reactionundecaprenyldiphospho, muramoylpentapepti. In enzymology an undecaprenyldiphospho muramoylpentapeptide beta N acetylglucosaminyltransferase EC 2 4 1 227 is an enzyme that catalyzes the chemical reactionundecaprenyldiphospho muramoylpentapeptide beta N acetylglucosaminyltransferaseIdentifiersEC no 2 4 1 227CAS no 60976 26 3DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumGene OntologyAmiGO QuickGOSearchPMCarticlesPubMedarticlesNCBIproteins UDP N acetylglucosamine Mur2Ac oyl L Ala gamma D Glu L Lys D Ala D Ala diphosphoundecaprenol displaystyle rightleftharpoons UDP GlcNAc 1 gt 4 Mur2Ac oyl L Ala gamma D Glu L Lys D Ala D Ala diphosphoundecaprenolThe 2 substrates of this enzyme are UDP N acetylglucosamine and Mur2Ac oyl L Ala gamma D Glu L Lys D Ala D Ala diphosphoundecaprenol whereas its 2 products are UDP and Lipid II This enzyme belongs to the family of glycosyltransferases specifically the hexosyltransferases The systematic name of this enzyme class is UDP N acetyl D glucosamine N acetyl alpha D muramyl oyl L Ala gamma D Glu L Lys D Ala D Ala diphosphoundecaprenol beta 1 4 N acetylglucosaminlytransferase Another name in common use is MurG transferase This enzyme participates in peptidoglycan biosynthesis Variant reactions producing modified cell walls include not muturally exclusive Replacement of lysine residue with meso diaminopimelate combined with adjacent residues through its L centre as it is in Gram negative and some Gram positive organisms 1 Use of mono trans octa cis decaprenyl instead of the conventional di trans octa cis undecaprenol moiety as found in Mycobacterium 2 References edit MetaCyc EC 2 4 1 227 biocyc org MetaCyc EC 2 4 1 227 biocyc org van Heijenoort J October 2001 Recent advances in the formation of the bacterial peptidoglycan monomer unit Natural Product Reports 18 5 503 19 doi 10 1039 a804532a PMID 11699883 Portal nbsp Biology This EC 2 4 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Undecaprenyldiphospho muramoylpentapeptide beta N acetylglucosaminyltransferase amp oldid 1172365055, wikipedia, wiki, book, books, library,
