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Mucinous nevus

Mucinous nevus is a rare cutaneous condition characterized by hamartoma that can be congenital or acquired.[1] Mucinous nevus presents as multiple skin-coloured or brown asymptomatic papules or plaques. Mucinous nevus is diagnosed based of histological features. Treatment is not needed.

Mucinous nevus
Other namesNevus mucinosus
SpecialtyDermatology

Signs and symptoms edit

Mucinous nevus appears as several skin-coloured to brownish papules or plaques that are asymptomatic; the individual lesions merge and expand to form a unilateral or zosteriform feature that is verrucous or nevoid.[2][3] It normally starts to develop in early adulthood or from birth.[4] The main location is the trunk, which includes the back.[2][5]

Causes edit

There has been reports of familial mucinous nevus, however there have been no reports of genetic abnormalities.[5][4]

Diagnosis edit

Histologically, diffuse band-like mucin deposits in the uppermost layer of the dermis are indicative of mucinous nevus.[6] Hyaluronic acid is assumed to be the component of mucin since it reacts positively with alcian blue at pH 2.5 but does not at pH 0.5.[7][8]

Treatment edit

Mucinous nevi are benign and don't need to be treated other than for aesthetic reasons.[2] Carbon dioxide laser therapy, scalpel dermabrasion, and surgical excision are treatment options.[9]

See also edit

References edit

  1. ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
  2. ^ a b c Cobos, Gabriela; Braunstein, Inbal; Abuabara, Katrina; Chu, Emily Y.; James, William (2014-09-01). "Mucinous Nevus: Report of a Case and Review of the Literature". JAMA Dermatology. 150 (9): 1018. doi:10.1001/jamadermatol.2013.9451. ISSN 2168-6068. PMID 25029469.
  3. ^ Tardío, Juan C.; Granados, Rosario (2010-07-08). "The cellular component of the mucinous nevus consists of CD34-positive fibroblasts". Journal of Cutaneous Pathology. 37 (9). Wiley: 1019–1020. doi:10.1111/j.1600-0560.2009.01426.x. ISSN 0303-6987. PMID 19765172.
  4. ^ a b CHEN, CHIA-WEI; TSAI, TSEN-FANG; CHEN, YU-FU; HUNG, CHIH-MING (2008). "Familial Mucinous Nevus". Pediatric Dermatology. 25 (2). Wiley: 288–289. doi:10.1111/j.1525-1470.2008.00664.x. ISSN 0736-8046. PMID 18429813.
  5. ^ a b Perez-Crespo, M; Lopez-Navarro, N; Betlloch, I; Herrera, E; Niveiro, M; Gallego, E (2011-09-25). "Acquired and familial mucinous nevus". International Journal of Dermatology. 50 (10). Wiley: 1283–1285. doi:10.1111/j.1365-4632.2010.04520.x. ISSN 0011-9059. PMID 21950298.
  6. ^ Lee, Min Young; Byun, Ji Yeon; Choi, Hae Young; Choi, You Won (2018). "Mucinous Nevus". Annals of Dermatology. 30 (4). Korean Dermatological Association and The Korean Society for Investigative Dermatology: 465–467. doi:10.5021/ad.2018.30.4.465. ISSN 1013-9087. PMC 6029955. PMID 30065589.
  7. ^ Lim, J-H.; Cho, S-H.; Kim, H-O.; Kim, C-W.; Park, Y-M. (2003). "Mucinous naevus with atypical features". British Journal of Dermatology. 148 (5). Oxford University Press (OUP): 1064–1066. doi:10.1046/j.1365-2133.2003.05334.x. ISSN 0007-0963. PMID 12786849.
  8. ^ BRAKMAN, M.; STARINK, TH.M.; TAFELKRUYER, J.; BOS, J.D. (1994). "Linear connective tissue naevus of the proteoglycan type ('naevus mucinosus')". British Journal of Dermatology. 131 (3). Oxford University Press (OUP): 368–370. doi:10.1111/j.1365-2133.1994.tb08526.x. ISSN 0007-0963.
  9. ^ Chi, Ching-Chi; Wang, Shu-Hui; Lin, Paul Y. (2009). "Combined epidermal-connective tissue nevus of proteoglycan (a type of mucinous nevus): a case report and literature review". Journal of Cutaneous Pathology. 36 (7). Wiley: 808–811. doi:10.1111/j.1600-0560.2008.01123.x. ISSN 0303-6987. PMID 19519615.

Further reading edit

  • Song, Byong Han; Park, Saebomi; Park, Eun Joo; Kwon, In Ho; Kim, Kwang Ho; Kim, Kwang Joong (2012). "Mucinous Nevus With Fat". The American Journal of Dermatopathology. 34 (8). Ovid Technologies (Wolters Kluwer Health): e146–e148. doi:10.1097/dad.0b013e31825a8b46. ISSN 0193-1091. PMID 22878365.
  • Kim, Eun Jee; Jo, Seong-Jin; Cho, Kwang Hyun (2014). "A Case of Mucinous Nevus Clinically Mimicking Nevus Lipomatosus Superficialis". Annals of Dermatology. 26 (4). Korean Dermatological Association and The Korean Society for Investigative Dermatology: 549–550. doi:10.5021/ad.2014.26.4.549. ISSN 1013-9087. PMC 4135125. PMID 25143699.

External links edit

mucinous, nevus, rare, cutaneous, condition, characterized, hamartoma, that, congenital, acquired, presents, multiple, skin, coloured, brown, asymptomatic, papules, plaques, diagnosed, based, histological, features, treatment, needed, other, namesnevus, mucino. Mucinous nevus is a rare cutaneous condition characterized by hamartoma that can be congenital or acquired 1 Mucinous nevus presents as multiple skin coloured or brown asymptomatic papules or plaques Mucinous nevus is diagnosed based of histological features Treatment is not needed Mucinous nevusOther namesNevus mucinosusSpecialtyDermatology Contents 1 Signs and symptoms 2 Causes 3 Diagnosis 4 Treatment 5 See also 6 References 7 Further reading 8 External linksSigns and symptoms editMucinous nevus appears as several skin coloured to brownish papules or plaques that are asymptomatic the individual lesions merge and expand to form a unilateral or zosteriform feature that is verrucous or nevoid 2 3 It normally starts to develop in early adulthood or from birth 4 The main location is the trunk which includes the back 2 5 Causes editThere has been reports of familial mucinous nevus however there have been no reports of genetic abnormalities 5 4 Diagnosis editHistologically diffuse band like mucin deposits in the uppermost layer of the dermis are indicative of mucinous nevus 6 Hyaluronic acid is assumed to be the component of mucin since it reacts positively with alcian blue at pH 2 5 but does not at pH 0 5 7 8 Treatment editMucinous nevi are benign and don t need to be treated other than for aesthetic reasons 2 Carbon dioxide laser therapy scalpel dermabrasion and surgical excision are treatment options 9 See also editMRI burn List of cutaneous conditionsReferences edit Rapini Ronald P Bolognia Jean L Jorizzo Joseph L 2007 Dermatology 2 Volume Set St Louis Mosby ISBN 978 1 4160 2999 1 a b c Cobos Gabriela Braunstein Inbal Abuabara Katrina Chu Emily Y James William 2014 09 01 Mucinous Nevus Report of a Case and Review of the Literature JAMA Dermatology 150 9 1018 doi 10 1001 jamadermatol 2013 9451 ISSN 2168 6068 PMID 25029469 Tardio Juan C Granados Rosario 2010 07 08 The cellular component of the mucinous nevus consists of CD34 positive fibroblasts Journal of Cutaneous Pathology 37 9 Wiley 1019 1020 doi 10 1111 j 1600 0560 2009 01426 x ISSN 0303 6987 PMID 19765172 a b CHEN CHIA WEI TSAI TSEN FANG CHEN YU FU HUNG CHIH MING 2008 Familial Mucinous Nevus Pediatric Dermatology 25 2 Wiley 288 289 doi 10 1111 j 1525 1470 2008 00664 x ISSN 0736 8046 PMID 18429813 a b Perez Crespo M Lopez Navarro N Betlloch I Herrera E Niveiro M Gallego E 2011 09 25 Acquired and familial mucinous nevus International Journal of Dermatology 50 10 Wiley 1283 1285 doi 10 1111 j 1365 4632 2010 04520 x ISSN 0011 9059 PMID 21950298 Lee Min Young Byun Ji Yeon Choi Hae Young Choi You Won 2018 Mucinous Nevus Annals of Dermatology 30 4 Korean Dermatological Association and The Korean Society for Investigative Dermatology 465 467 doi 10 5021 ad 2018 30 4 465 ISSN 1013 9087 PMC 6029955 PMID 30065589 Lim J H Cho S H Kim H O Kim C W Park Y M 2003 Mucinous naevus with atypical features British Journal of Dermatology 148 5 Oxford University Press OUP 1064 1066 doi 10 1046 j 1365 2133 2003 05334 x ISSN 0007 0963 PMID 12786849 BRAKMAN M STARINK TH M TAFELKRUYER J BOS J D 1994 Linear connective tissue naevus of the proteoglycan type naevus mucinosus British Journal of Dermatology 131 3 Oxford University Press OUP 368 370 doi 10 1111 j 1365 2133 1994 tb08526 x ISSN 0007 0963 Chi Ching Chi Wang Shu Hui Lin Paul Y 2009 Combined epidermal connective tissue nevus of proteoglycan a type of mucinous nevus a case report and literature review Journal of Cutaneous Pathology 36 7 Wiley 808 811 doi 10 1111 j 1600 0560 2008 01123 x ISSN 0303 6987 PMID 19519615 Further reading editSong Byong Han Park Saebomi Park Eun Joo Kwon In Ho Kim Kwang Ho Kim Kwang Joong 2012 Mucinous Nevus With Fat The American Journal of Dermatopathology 34 8 Ovid Technologies Wolters Kluwer Health e146 e148 doi 10 1097 dad 0b013e31825a8b46 ISSN 0193 1091 PMID 22878365 Kim Eun Jee Jo Seong Jin Cho Kwang Hyun 2014 A Case of Mucinous Nevus Clinically Mimicking Nevus Lipomatosus Superficialis Annals of Dermatology 26 4 Korean Dermatological Association and The Korean Society for Investigative Dermatology 549 550 doi 10 5021 ad 2014 26 4 549 ISSN 1013 9087 PMC 4135125 PMID 25143699 External links edit Retrieved from https en wikipedia org w index php title Mucinous nevus amp oldid 1218163210, wikipedia, wiki, book, books, library,

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