This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 5-methyl-5-thio-D-ribulose-1-phosphate 4-hydro-lyase [5-(methylthio)-2,3-dioxopentyl-phosphate-forming]. Other names in common use include 1-PMT-ribulose dehydratase, and S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase. This enzyme participates in methionine metabolism.
Referencesedit
^Kang, W; Hong, S. H.; Lee, H. M.; Kim, N. Y.; Lim, Y. C.; Le Le, T. M.; Lim, B; Kim, H. C.; Kim, T. Y.; Ashida, H; Yokota, A; Hah, S. S.; Chun, K. H.; Jung, Y. K.; Yang, J. K. (2014). "Structural and biochemical basis for the inhibition of cell death by APIP, a methionine salvage enzyme". Proceedings of the National Academy of Sciences. 111 (1): E54-61. Bibcode:2014PNAS..111E..54K. doi:10.1073/pnas.1308768111. PMC3890807. PMID 24367089.
Furfine ES, Abeles RH (1988). "Intermediates in the conversion of 5'-S-methylthioadenosine to methionine in Klebsiella pneumoniae". J. Biol. Chem. 263 (20): 9598–606. doi:10.1016/S0021-9258(19)81558-2. PMID 2838472.
Wray JW, Abeles RH (1995). "The methionine salvage pathway in Klebsiella pneumoniae and rat liver. Identification and characterization of two novel dioxygenases". J. Biol. Chem. 270 (7): 3147–53. doi:10.1074/jbc.270.7.3147. PMID 7852397.
methylthioribulose, phosphate, dehydratase, enzyme, methylthioribulose, phosphate, dehydratase, catalyzes, chemical, reactionmethylthioribulose, phosphate, dehydratasex, structure, human, methylthioribulose, phosphate, dehydratase, apip, entry, 4m6r, identifie. The enzyme methylthioribulose 1 phosphate dehydratase EC 2 1 109 catalyzes the chemical reactionmethylthioribulose 1 phosphate dehydrataseX ray structure of human methylthioribulose 1 phosphate dehydratase APIP PDB entry 4m6r 1 IdentifiersEC no 4 2 1 109DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumGene OntologyAmiGO QuickGOSearchPMCarticlesPubMedarticlesNCBIproteins 5 methylsulfanyl D ribulose 1 phosphate displaystyle rightleftharpoons 5 methylthio 2 3 dioxopentyl phosphate H2 This enzyme belongs to the family of lyases specifically the hydro lyases which cleave carbon oxygen bonds The systematic name of this enzyme class is 5 methyl 5 thio D ribulose 1 phosphate 4 hydro lyase 5 methylthio 2 3 dioxopentyl phosphate forming Other names in common use include 1 PMT ribulose dehydratase and S methyl 5 thio D ribulose 1 phosphate hydro lyase This enzyme participates in methionine metabolism References edit Kang W Hong S H Lee H M Kim N Y Lim Y C Le Le T M Lim B Kim H C Kim T Y Ashida H Yokota A Hah S S Chun K H Jung Y K Yang J K 2014 Structural and biochemical basis for the inhibition of cell death by APIP a methionine salvage enzyme Proceedings of the National Academy of Sciences 111 1 E54 61 Bibcode 2014PNAS 111E 54K doi 10 1073 pnas 1308768111 PMC 3890807 PMID 24367089 Furfine ES Abeles RH 1988 Intermediates in the conversion of 5 S methylthioadenosine to methionine in Klebsiella pneumoniae J Biol Chem 263 20 9598 606 doi 10 1016 S0021 9258 19 81558 2 PMID 2838472 Wray JW Abeles RH 1995 The methionine salvage pathway in Klebsiella pneumoniae and rat liver Identification and characterization of two novel dioxygenases J Biol Chem 270 7 3147 53 doi 10 1074 jbc 270 7 3147 PMID 7852397 Portal nbsp Biology This EC 4 2 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Methylthioribulose 1 phosphate dehydratase amp oldid 1172353553, wikipedia, wiki, book, books, library,
