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List of keratins

The first sequences of keratins revealed that keratins could be grouped into two categories based on their sequence homologies.[1][2] These two groups of keratins were named as type I and type II keratins.[2] These two categories also represent the first two categories of the superfamily of intermediate filament proteins.

Keratins in this table are classified in the first two columns according to the nomenclature established in 2006.[3] Other names previously used are listed in columns 3 and 4.

Type I keratins edit

Human epithelial keratins edit

Protein name[3] Gene name[3] Other protein name Other gene name
K9 KRT9 Ka9
K10 KRT10 Ka10
K12 KRT12 Ka12
K13 KRT13 Ka13
K14 KRT14 Ka14
K15 KRT15 Ka15
K16 KRT16 Ka16
K17 KRT17 Ka17
K18 KRT18 Ka18
K19 KRT19 Ka19
K20 KRT20 Ka20
K23 KRT23 Ka23
K24 KRT24 Ka24
K25 KRT25 Ka38, K25irs1, K10C, hIRSa1 KRT25A
K26 KRT26 Ka39, K25irs2, K10D
K27 KRT27 Ka40, K25irs3, K10B, hIRSa3.1
K28 KRT28 Ka41, K25irs4, hIRSa2

Human hair keratins edit

Protein name[3] Gene name[3] Other protein name Other gene name
K31 KRT31 Ka25, Ha1 KRTHA1
K32 KRT32 Ka26, Ha2 KRTHA2
K33a KRT33A Ka27, Ha3-I KRTHA3A
K33b KRT33B Ka28, Ha3-II KRTHA3B
K34 KRT34 Ka29, Ha4 KRTHA4
K35 KRT35 Ka30, Ha5 KRTHA5
K36 KRT36 Ka31, Ha6 KRTHA6
K37 KRT37 Ka32, Ha7 KRTHA7
K38 KRT38 Ka33, Ha8 KRTHA8
K39 KRT39 Ka35
K40 KRT40 Ka36

Nonhuman hair/epithelial keratins edit

Protein name[3] Gene name[3] Other protein name Other gene name
K41 chimp, gorilla KRT41 chimp, gorilla, KRT41P man φhHaA, Ka34P man
K42 mouse, rat KRT42 mouse, rat, KRT42P man Ka22 mouse, rat, K17n mouse, rat

Human keratin pseudogenes edit

Protein name[3] Gene name[3] Other protein name Other gene name
KRT221P φhHaB
KRT222P φKRTI, Ka21P
KRT223P φKRTJ, Ka37P

Type II keratins edit

Human epithelial keratin edit

Protein name[3] Gene name[3] Other protein name Other gene name
K1 KRT1 Kb1
K2 KRT2 Kb2, K2e KRT2A
K3 KRT3 Kb3
K4 KRT4 Kb4
K5 KRT5 Kb5
K6a KRT6A Kb6
K6b KRT6B Kb10
K7 KRT7 Kb7
K8 KRT8 Kb8
K71 KRT71 Kb34, K6irs1
K72 KRT72 Kb35, K6irs2
K73 KRT73 Kb36, K6irs3
K74 KRT74 Kb37, K6irs4
K75 KRT75 Kb18, K6hf
K76 KRT76 Kb9, K2p KRT2B
K77 KRT77 Kb39, K1b
K78 KRT78 Kb40, K5b
K79 KRT79 Kb38, K6I
K80 KRT80 Kb20

Human hair keratins edit

Protein name[3] Gene name[3] Other protein name Other gene name
K81 KRT81 Kb21, Hb1, K2.9 KRTHB1
K82 KRT82 Kb22, Hb2 KRTHB2
K83 KRT83 Kb23, Hb3, K2.10 KRTHB3
K84 KRT84 Kb24, Hb4 KRTHB4
K85 KRT85 Kb25, Hb5, K2.12 KRTHB5
K86 KRT86 Kb26, Hb6, K2.11 KRTHB6

Human keratin pseudogenes edit

Protein name[3] Gene name[3] Other protein name Other gene name
KRT121P φhHbD, Kb31P
KRT122P φhHbC, Kb30P
KRT123P φhHbB, Kb29P
KRT124P φhHbA, Kb28P
KRT125P φKRTH
KRT126P φKRTG, Kb19P
KRT127P φKRTF
KRT128P φKRTE

See also edit

References edit

  1. ^ Hanukoglu, I.; Fuchs, E. (Nov 1982). "The cDNA sequence of a human epidermal keratin: divergence of sequence but conservation of structure among intermediate filament proteins". Cell. 31 (1): 243–52. doi:10.1016/0092-8674(82)90424-X. PMID 6186381. S2CID 35796315.
  2. ^ a b Hanukoglu, I.; Fuchs, E. (Jul 1983). "The cDNA sequence of a Type II cytoskeletal keratin reveals constant and variable structural domains among keratins". Cell. 33 (3): 915–24. doi:10.1016/0092-8674(83)90034-X. PMID 6191871. S2CID 21490380.
  3. ^ a b c d e f g h i j k l m n o Schweizer J, Bowden PE, Coulombe PA, et al. (July 2006). "New consensus nomenclature for mammalian keratins". J. Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889.

list, keratins, first, sequences, keratins, revealed, that, keratins, could, grouped, into, categories, based, their, sequence, homologies, these, groups, keratins, were, named, type, type, keratins, these, categories, also, represent, first, categories, super. The first sequences of keratins revealed that keratins could be grouped into two categories based on their sequence homologies 1 2 These two groups of keratins were named as type I and type II keratins 2 These two categories also represent the first two categories of the superfamily of intermediate filament proteins Keratins in this table are classified in the first two columns according to the nomenclature established in 2006 3 Other names previously used are listed in columns 3 and 4 Contents 1 Type I keratins 1 1 Human epithelial keratins 1 2 Human hair keratins 1 3 Nonhuman hair epithelial keratins 1 4 Human keratin pseudogenes 2 Type II keratins 2 1 Human epithelial keratin 2 2 Human hair keratins 2 3 Human keratin pseudogenes 3 See also 4 ReferencesType I keratins editHuman epithelial keratins edit Protein name 3 Gene name 3 Other protein name Other gene nameK9 KRT9 Ka9K10 KRT10 Ka10K12 KRT12 Ka12K13 KRT13 Ka13K14 KRT14 Ka14K15 KRT15 Ka15K16 KRT16 Ka16K17 KRT17 Ka17K18 KRT18 Ka18K19 KRT19 Ka19K20 KRT20 Ka20K23 KRT23 Ka23K24 KRT24 Ka24K25 KRT25 Ka38 K25irs1 K10C hIRSa1 KRT25AK26 KRT26 Ka39 K25irs2 K10DK27 KRT27 Ka40 K25irs3 K10B hIRSa3 1K28 KRT28 Ka41 K25irs4 hIRSa2Human hair keratins edit Protein name 3 Gene name 3 Other protein name Other gene nameK31 KRT31 Ka25 Ha1 KRTHA1K32 KRT32 Ka26 Ha2 KRTHA2K33a KRT33A Ka27 Ha3 I KRTHA3AK33b KRT33B Ka28 Ha3 II KRTHA3BK34 KRT34 Ka29 Ha4 KRTHA4K35 KRT35 Ka30 Ha5 KRTHA5K36 KRT36 Ka31 Ha6 KRTHA6K37 KRT37 Ka32 Ha7 KRTHA7K38 KRT38 Ka33 Ha8 KRTHA8K39 KRT39 Ka35K40 KRT40 Ka36Nonhuman hair epithelial keratins edit Protein name 3 Gene name 3 Other protein name Other gene nameK41 chimp gorilla KRT41 chimp gorilla KRT41P man fhHaA Ka34P manK42 mouse rat KRT42 mouse rat KRT42P man Ka22 mouse rat K17n mouse ratHuman keratin pseudogenes edit Protein name 3 Gene name 3 Other protein name Other gene nameKRT221P fhHaBKRT222P fKRTI Ka21PKRT223P fKRTJ Ka37PType II keratins editHuman epithelial keratin edit Protein name 3 Gene name 3 Other protein name Other gene nameK1 KRT1 Kb1K2 KRT2 Kb2 K2e KRT2AK3 KRT3 Kb3K4 KRT4 Kb4K5 KRT5 Kb5K6a KRT6A Kb6K6b KRT6B Kb10K7 KRT7 Kb7K8 KRT8 Kb8K71 KRT71 Kb34 K6irs1K72 KRT72 Kb35 K6irs2K73 KRT73 Kb36 K6irs3K74 KRT74 Kb37 K6irs4K75 KRT75 Kb18 K6hfK76 KRT76 Kb9 K2p KRT2BK77 KRT77 Kb39 K1bK78 KRT78 Kb40 K5bK79 KRT79 Kb38 K6IK80 KRT80 Kb20Human hair keratins edit Protein name 3 Gene name 3 Other protein name Other gene nameK81 KRT81 Kb21 Hb1 K2 9 KRTHB1K82 KRT82 Kb22 Hb2 KRTHB2K83 KRT83 Kb23 Hb3 K2 10 KRTHB3K84 KRT84 Kb24 Hb4 KRTHB4K85 KRT85 Kb25 Hb5 K2 12 KRTHB5K86 KRT86 Kb26 Hb6 K2 11 KRTHB6Human keratin pseudogenes edit Protein name 3 Gene name 3 Other protein name Other gene nameKRT121P fhHbD Kb31PKRT122P fhHbC Kb30PKRT123P fhHbB Kb29PKRT124P fhHbA Kb28PKRT125P fKRTHKRT126P fKRTG Kb19PKRT127P fKRTFKRT128P fKRTESee also editKeratins Skin EpidermisReferences edit Hanukoglu I Fuchs E Nov 1982 The cDNA sequence of a human epidermal keratin divergence of sequence but conservation of structure among intermediate filament proteins Cell 31 1 243 52 doi 10 1016 0092 8674 82 90424 X PMID 6186381 S2CID 35796315 a b Hanukoglu I Fuchs E Jul 1983 The cDNA sequence of a Type II cytoskeletal keratin reveals constant and variable structural domains among keratins Cell 33 3 915 24 doi 10 1016 0092 8674 83 90034 X PMID 6191871 S2CID 21490380 a b c d e f g h i j k l m n o Schweizer J Bowden PE Coulombe PA et al July 2006 New consensus nomenclature for mammalian keratins J Cell Biol 174 2 169 74 doi 10 1083 jcb 200603161 PMC 2064177 PMID 16831889 Retrieved from https en wikipedia org w index php title List of keratins amp oldid 1157841517, wikipedia, wiki, book, books, library,

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