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Linoleate 10R-lipoxygenase

Linoleate 10R-lipoxygenase (EC 1.13.11.62, 10R-DOX, (10R)-dioxygenase, 10R-dioxygenase) is an enzyme with systematic name linoleate:oxygen (10R)-oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction

Linoleate 10R-lipoxygenase
Identifiers
EC no.1.13.11.62
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
linoleate + O2 (8E,10R,12Z)-10-hydroperoxy-8,12-octadecadienoate

Linoleate 10R-lipoxygenase is involved in biosynthesis of oxylipins.

References edit

  1. ^ Garscha U, Oliw EH (May 2009). "Leucine/valine residues direct oxygenation of linoleic acid by (10R)- and (8R)-dioxygenases: expression and site-directed mutagenesis oF (10R)-dioxygenase with epoxyalcohol synthase activity". The Journal of Biological Chemistry. 284 (20): 13755–65. doi:10.1074/jbc.M808665200. PMC 2679477. PMID 19289462.
  2. ^ Jernerén F, Garscha U, Hoffmann I, Hamberg M, Oliw EH (April 2010). "Reaction mechanism of 5,8-linoleate diol synthase, 10R-dioxygenase, and 8,11-hydroperoxide isomerase of Aspergillus clavatus". Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1801 (4): 503–7. doi:10.1016/j.bbalip.2009.12.012. PMID 20045744.

External links edit

linoleate, lipoxygenase, dioxygenase, dioxygenase, enzyme, with, systematic, name, linoleate, oxygen, oxidoreductase, this, enzyme, catalyses, following, chemical, reactionidentifiersec, 62databasesintenzintenz, viewbrendabrenda, entryexpasynicezyme, viewkeggk. Linoleate 10R lipoxygenase EC 1 13 11 62 10R DOX 10R dioxygenase 10R dioxygenase is an enzyme with systematic name linoleate oxygen 10R oxidoreductase 1 2 This enzyme catalyses the following chemical reactionLinoleate 10R lipoxygenaseIdentifiersEC no 1 13 11 62DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumSearchPMCarticlesPubMedarticlesNCBIproteins linoleate O2 displaystyle rightleftharpoons 8E 10R 12Z 10 hydroperoxy 8 12 octadecadienoate Linoleate 10R lipoxygenase is involved in biosynthesis of oxylipins References edit Garscha U Oliw EH May 2009 Leucine valine residues direct oxygenation of linoleic acid by 10R and 8R dioxygenases expression and site directed mutagenesis oF 10R dioxygenase with epoxyalcohol synthase activity The Journal of Biological Chemistry 284 20 13755 65 doi 10 1074 jbc M808665200 PMC 2679477 PMID 19289462 Jerneren F Garscha U Hoffmann I Hamberg M Oliw EH April 2010 Reaction mechanism of 5 8 linoleate diol synthase 10R dioxygenase and 8 11 hydroperoxide isomerase of Aspergillus clavatus Biochimica et Biophysica Acta BBA Molecular and Cell Biology of Lipids 1801 4 503 7 doi 10 1016 j bbalip 2009 12 012 PMID 20045744 External links editLinoleate 10R lipoxygenase at the U S National Library of Medicine Medical Subject Headings MeSH Portal nbsp Biology Retrieved from https en wikipedia org w index php title Linoleate 10R lipoxygenase amp oldid 1172352105, wikipedia, wiki, book, books, library,

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