Laser direct infrared imaging (LDIR) is an infrared microscopy architecture that utilizes a tunable Quantum Cascade Laser (QCL) as the IR source.[1] This new reflectance-based architecture eliminates coherence artifacts typically associated with QCLs. It also allows the acquisition of large-area, high-definition IR images as well as high signal-to-noise point spectra. Extending this architecture using Attenuated Total Reflectance (ATR) allows the acquisition of high fidelity spectra from features less than 10 μm in size.[2]
The application of LDIR to stain-free biochemical imaging has recently been reported,[3] with the authors citing the speed of LDIR imaging as an advantage over traditional IR imaging architectures.
Referencesedit
^Hoke, C.; Beregovski, Y.; Ghetler, A.; Han, Y.; Moon, C.; Tella, R. (2015). "Laser Direct IR Imaging - A New Paradigm for Mid-IR Spectroscopic Imaging." (PDF). Proceedings of SciX 2015 (FACSS XLII), Providence, Rhode Island, 569.
^Hoke, C.; Beregovski, Y.; Ghetler, A.; Han, Y.; Moon, C.; Tella, R.; Zhang, Z. (2016). "Advances in Laser Direct IR Imaging". Proceedings of SciX 2016, Minneapolis, Minnseota, 16IR07.
^Tiwari, S.; Raman, J.; Reddy, V.; Ghetler, A.; Tella, R.; Han, Y.; Moon, C.; Hoke, C.; Bhargava, R. (2016). "Towards Translation of Discrete Frequency Infrared Spectroscopic Imaging for Digital Histopathology of Clinical Biopsy Samples". Analytical Chemistry. 88 (20): 10183–10190. doi:10.1021/acs.analchem.6b02754. PMID 27626947.
January 01, 1970
laser, direct, infrared, imaging, ldir, infrared, microscopy, architecture, that, utilizes, tunable, quantum, cascade, laser, source, this, reflectance, based, architecture, eliminates, coherence, artifacts, typically, associated, with, qcls, also, allows, acq. Laser direct infrared imaging LDIR is an infrared microscopy architecture that utilizes a tunable Quantum Cascade Laser QCL as the IR source 1 This new reflectance based architecture eliminates coherence artifacts typically associated with QCLs It also allows the acquisition of large area high definition IR images as well as high signal to noise point spectra Extending this architecture using Attenuated Total Reflectance ATR allows the acquisition of high fidelity spectra from features less than 10 mm in size 2 The application of LDIR to stain free biochemical imaging has recently been reported 3 with the authors citing the speed of LDIR imaging as an advantage over traditional IR imaging architectures References edit Hoke C Beregovski Y Ghetler A Han Y Moon C Tella R 2015 Laser Direct IR Imaging A New Paradigm for Mid IR Spectroscopic Imaging PDF Proceedings of SciX 2015 FACSS XLII Providence Rhode Island 569 Hoke C Beregovski Y Ghetler A Han Y Moon C Tella R Zhang Z 2016 Advances in Laser Direct IR Imaging Proceedings of SciX 2016 Minneapolis Minnseota 16IR07 Tiwari S Raman J Reddy V Ghetler A Tella R Han Y Moon C Hoke C Bhargava R 2016 Towards Translation of Discrete Frequency Infrared Spectroscopic Imaging for Digital Histopathology of Clinical Biopsy Samples Analytical Chemistry 88 20 10183 10190 doi 10 1021 acs analchem 6b02754 PMID 27626947 Retrieved from https en wikipedia org w index php title Laser direct infrared imaging amp oldid 1138872881, wikipedia, wiki, book, books, library,
