LGC Ltd
LGC Group, formerly the Laboratory of the Government Chemist, is an international life sciences measurement and tools company. It provides the role and duties of the UK Government Chemist, a statutory adviser to the government. LGC also hosts the UK's National Measurement Laboratory (NML) for chemical and bio-measurement,[1] which performs measurements for diagnostics, advanced therapeutics, safety and security, among others.
| Type | Private limited company |
|---|---|
| Industry | biotechnology industry |
| Predecessor | Laboratory of the Government Chemist; origins in 1842 |
| Founded | February 1996 |
| Headquarters | Teddington, England |
Area served | Global |
Key people | Euan O'Sullivan (Chief Executive) |
| Revenue | £156 million (2022) |
| £5 million | |
| (£22 million) (2022) | |
Number of employees | 1,166 |
| Parent | Consortium led by Cinven and Astorg |
| Website | www |
Functions edit
This article contains content that is written like an advertisement. (November 2021) |
LGC provides measurement products and services, including reference materials and proficiency testing, genomics reagents and instrumentation, and sample analysis and interpretation. LGC serves customers in pharmaceuticals, agricultural biotechnology, diagnostics, and others.
LGC operates through the genomics and standards divisions.
In the genomics division, the offering has been built around core capabilities that are intended for many genomics applications:
- Nucleic acid chemistry, specifically the design, development, and manufacture of complex and modified oligonucleotides and related products for molecular diagnostics and therapeutics;
- Molecular biology, specifically the design and engineering of reagents, kits, and other critical components, including enzymes, sample preparation magnetic beads, instruments, and consumables for use in polymerase chain reaction (PCR) and next generation sequencing workflows;
- Complete PCR workflow products intended for high-throughput PCR applications.
The standards offering has been built around capabilities that are used for quality assurance applications:
- Quality control materials for use by clinical and molecular diagnostics customers to support assay development and commercialisation, as well as the delivery of consistently accurate measurements in clinical laboratories, while proficiency testing schemes provide a framework for regular, independent assessment of laboratory performance;
- Reference materials and analytical standards for pharmaceutical and applied market segments for development, validation, and quality control of analytical testing methods, from applied research and discovery through to analytical testing laboratories and the final manufacturing of drug products;
- Supply chain assurance products for organisations in the food, beverage, and consumer safety market segments to support consistent quality criteria through the supply chain, including management system standards used by food manufacturing sites, proficiency testing schemes, consumer-facing endorsement marks, and provision of digital supply chain management products.
LGC used to participate in the European Reference Materials consortium, together with the Institute for Reference Materials and Measurements of the European Commission's Directorate General Joint Research Centre and the Bundesanstalt für Materialforschung und -prüfung, Germany (BAM).[citation needed]
UK Government Chemist edit
The Government Chemist is a person appointed with statutory duties prescribed in seven acts of Parliament, supported by the Laboratory of the Government Chemist. In addition, this person is an advisor to the government on relevant matters. As of 2018, both these functions are funded by the Department for Business, Energy and Industrial Strategy, but LGC is a private company, and the Government Chemist is an employee of LGC.[2] As of August 2023, this position is held by Dr Julian Braybrook.[3]
History edit
Origins edit
In 1842 the Department of Excise set up a laboratory in its Broad Street headquarters to check tobacco for adulteration, i.e. the addition of other substances to increase profits and evade duty, (the amount of tobacco sold was much greater than imported). One employee, George Phillips, used a microscope and chemical tests, most of which he had developed himself. The work of the laboratory expanded to check for adulteration in pepper, beer and coffee with additional staff being employed under Phillips, and a new laboratory was opened in Somerset House in 1859, by which time Excise had joined the Inland Revenue. In 1861 it dealt with 11,000 samples. The work also expanded to include foodstuffs and soap, and in 1874 Phillips had 12 permanent staff. The Inland Revenue Laboratory, as it was now known, was appointed a Referee Analyst under the Sale of Food and Drugs Act 1875, i.e. one whose findings were accepted in a court of law. This greatly added to the number of samples being submitted.[4][5]
In 1894 an official Government Laboratory was set up, combining both the Inland Revenue Laboratory and a separate Customs Laboratory which had been set up in 1860, moving to purpose-built premises in Clement's Inn Passage in 1897.[6] The head was Dr Edward Thorpe, with the title of Principal Chemist, who expanded its activities to include health problems caused by the match and lead-glazing industries.[5] His report of 1907 states that 173,606 analyses and examinations were made on behalf of the departments of Customs & Excise, other departments, and in connection with two acts, the Food And Drugs Act and the Fertilisers and Feeding Stuffs Act.[7]
First Government Chemist edit
In 1911 the Government Laboratory became an independent government department, the Department of the Government Chemist. The Principal, Dr James Dobbie, was the first to be given the new title of Government Chemist.[4][5] The analysis of tobacco remained a substantial part of the work, being greatly increased during World War I because of supplies to troops.[4] Demand increased with interwar legislation, and the Laboratory had to do considerable original research to develop new and better analysis methods. The number of routine samples between 1920 and 1939 went from 199,388 to 430,314.[4] It was also asked by the government to look into methods associated with the carriage of dangerous goods, atmospheric pollution, and the possible dangers to health arising from the use of tetraethyllead in motor fuel.[5] World War II produced a peak demand of 560 354 samples.[5]
Creation of the Laboratory of the Government Chemist edit
In 1959 the Government Laboratory ceased to be a separate department but instead was brought under the Department of Scientific and Industrial Research. In 1963 it moved to new premises in Cornwall House, Waterloo, London as the Laboratory of the Government Chemist.[4] In 1989 it was changed into an Executive Agency under the Department of Trade and Industry.[8][9] This gave it the remit to seek outside work (which it already did to a significant extent) and earn income to fully cover costs, while having more management autonomy.[5] It also moved to new premises in Teddington.[4]
Privatisation edit
As part of a general programme of privatisation of public services by the government, Michael Heseltine announced that Laboratory of the Government Chemist would become an independent, non-profit company limited by guarantee, or could possibly be bought by a company or institution which could show that it would remain sufficiently independent to fulfil its statutory duties. However, the undertakings required to meet these obligations indefinitely meant that 40 initial expressions of interest produced only three considered suitable to bid, and no actual bids. A consortium of Laboratory employees, the Royal Society of Chemistry and 3i put together a bid in 1995, which was accepted, taking the form of a management buyout. It became LGC Ltd in February 1996.[9][8]
Post Privatisation edit
Since privatisation, LGC has changed ownership and significantly expanded its activities. Valued at £3 million when privatised, it was sold for £80 million in 2003 to LGV, part of Legal & General,[10] who sold it in 2010 to Bridgepoint Capital for £257 million, who in turn sold it in 2015 to KKR.[11] In 2020, KKR sold LGC to a consortium led by private equity companies Cinven and Astorg.[12]
Employee numbers have risen from 270 in 1996 to about 4,350 in 2021, as the company has grown organically and through multiple acquisitions. Acquisitions since 1996 include: KBioscience, AGOWA, Forensic Alliance Limited, Mikromol, Promochem, University Diagnostics Ltd, HFL, ARMI, VHG Labs, Quotient Bioanalytical Sciences, Dr Ehrenstorfer, Biosearch Technologies, Thistle QA, Maine Standards, Prime Synthesis, immunosuppressive proficiency testing (PT) scheme from ASI, BRC Global Standards, o2si, Seracare Life Sciences, Lucigen, Bioautomation, Berry & Associates, MBH Analytical, Toronto Research Chemicals, CDN Isotopes,, the Native Antigen Company, Safefood 360, Technopath Clinical Diagnostics, and Paragon; and the outsourcing of analytical services from BNG and Sentinel Performance Solutions.[citation needed]
See also edit
References edit
- ^ "UK National Measurement Laboratory". LGC Ltd. Retrieved 20 March 2021.
- ^ Cranston, Derek; Berryman, Paul (11 September 2018). "Government Chemist Review 2017" (PDF). Government of the United Kingdom. Retrieved 27 October 2018.
- ^ "Dr Julian Braybrook DSc, CChem FRSC - gov.uk". GOV.UK. Government of the United Kingdom. Retrieved 28 August 2023.
- ^ a b c d e f Hammond, P. W. (August 1992). "150 Years of the Laboratory of the Government Chemist". Analytical Proceedings. 29 (8): 311–314. doi:10.1039/ap992290311c.
- ^ a b c d e f Worswick, R. D. (June 1993). "Laboratory of the Government Chemist, Past and Future". Analyst. 118: 583–586. doi:10.1039/an9931800583.
- ^ Carson, Edward (1972). The Ancient and Rightful Customs. London: Faber & Faber. p. 295.
- ^ "Report of the Principal Chemist upon the work of the Government Laboratory for the year ending March 31, 1907". The Analyst. 32 (379): 375–6. 1907. doi:10.1039/AN9073200375.
- ^ a b Gains, Francesca (1999). "Implementing Privatization Policies in 'Next Steps' Agencies". Public Administration. 77 (4): 713–730. doi:10.1111/1467-9299.00176.
- ^ a b Frier, Peter; Birley, Sue (October 1999). "Management Buyouts in the Public Sector". Long Range Planning. 32 (5): 531–540. doi:10.1016/s0024-6301(99)00041-2.
- ^ Ebrahimi, Helia; Harrington, Ben (24 October 2009). "Forensics group LGC put up for sale". The Daily Telegraph. Retrieved 27 October 2018.
- ^ Walsh, Tessa (8 December 2015). "KKR wins battle for forensic science firm LGC". Reuters. Retrieved 27 October 2018.
- ^ "Annual Report and Accounts 2020" (PDF). LGC. LGC Science Group Holdings Limited. 9 September 2020. p. 7. Retrieved 8 June 2021.