Kurt Hellmann (12 May 1922 – 2 April 2013) was a Bavarian clinical pharmacologist best known for his discovery of the biologic activity of two important drugs: Razoxane & Dexrazoxane.[1][2]
CareerEdit
From 1962 until 1987, Hellmann served the Imperial Cancer Research Fund London as founding director of its Department of Cancer Chemotherapy.[3] In 1972, Hellmann published the results of his breakthrough work with DL-razoxane (ICRF-159), the first fully antimetastatic compound discovered for the treatment of cancer.[2] He was the co-founder and long-term editor (1974-1991) of the journal Cancer Treatment Reviews.[3] In 1974, he co-created with Silvio Garattini, the Director of the Mario Negri Institute for Pharmacological Research, Milan, an international body of medical experts called the E.O.R.T.C. Metastasis Club, which evolved in the 1980s into the Metastasis Research Society. He co-edited the organization's official journal, Clinical &Experimental Metastasis from 1984 to 1998. In 1977, he released with co-authors Stephen Carter and Marie Bakowski the oncology standard reference Chemotherapy of Cancer. In 1996, he predicted the importance of preventing pharmacological anthracycline cardiotoxicity in quality of life of cancer survivors.[2]
Personal life and educationEdit
A native of Nürnberg, Bavaria, Hellmann emigrated to England as a child in 1933.[3] After World War II service as an engineer, he turned his studies to chemistry at Oxford, receiving a Pharmacology Doctor of Philosophy degree in 1953, a Bachelor of Medicine, Bachelor of Surgery in 1958, and a Doctor of Medicine degree in 1964. During his studies, in 1959, he met his future wife, Jane, wedding her in 1961.[2] He had been a resident of East Sussex, UK, for over 30 years at the time of his death at the age of 90 in 2013. His wife survived him.[4]
ReferencesEdit
^HELLMANN K (September 1955). "Cholinesterase and amine oxidase in the skin: a histochemical investigation". The Journal of Physiology. 129 (3): 454–63. doi:10.1113/jphysiol.1955.sp005370. PMC1365976. PMID 13264109.
^ abcd"Kurt Hellman - a rare breed of medical and scientific humanitarian". Oncology News. 13 (2): 12–14. March–April 2018.
^ abcEccles, Suzanne A.; Steiner, Rudolf K. (2012-06-14). "Kurt Hellmann D.M., D.Phil. Oxon. A happy 90th birthday!". Clinical & Experimental Metastasis. 29 (6): 523–526. doi:10.1007/s10585-012-9490-4. ISSN 0262-0898. PMID 22695808.
^"metastasis-research.org | In Memoriam: Professor Kurt Hellmann". metastasis-research.org. Retrieved 2018-07-14.
September 02, 2023
kurt, hellmann, 1922, april, 2013, bavarian, clinical, pharmacologist, best, known, discovery, biologic, activity, important, drugs, razoxane, dexrazoxane, career, editfrom, 1962, until, 1987, hellmann, served, imperial, cancer, research, fund, london, foundin. Kurt Hellmann 12 May 1922 2 April 2013 was a Bavarian clinical pharmacologist best known for his discovery of the biologic activity of two important drugs Razoxane amp Dexrazoxane 1 2 Career EditFrom 1962 until 1987 Hellmann served the Imperial Cancer Research Fund London as founding director of its Department of Cancer Chemotherapy 3 In 1972 Hellmann published the results of his breakthrough work with DL razoxane ICRF 159 the first fully antimetastatic compound discovered for the treatment of cancer 2 He was the co founder and long term editor 1974 1991 of the journal Cancer Treatment Reviews 3 In 1974 he co created with Silvio Garattini the Director of the Mario Negri Institute for Pharmacological Research Milan an international body of medical experts called the E O R T C Metastasis Club which evolved in the 1980s into the Metastasis Research Society He co edited the organization s official journal Clinical amp Experimental Metastasis from 1984 to 1998 In 1977 he released with co authors Stephen Carter and Marie Bakowski the oncology standard reference Chemotherapy of Cancer In 1996 he predicted the importance of preventing pharmacological anthracycline cardiotoxicity in quality of life of cancer survivors 2 Personal life and education EditA native of Nurnberg Bavaria Hellmann emigrated to England as a child in 1933 3 After World War II service as an engineer he turned his studies to chemistry at Oxford receiving a Pharmacology Doctor of Philosophy degree in 1953 a Bachelor of Medicine Bachelor of Surgery in 1958 and a Doctor of Medicine degree in 1964 During his studies in 1959 he met his future wife Jane wedding her in 1961 2 He had been a resident of East Sussex UK for over 30 years at the time of his death at the age of 90 in 2013 His wife survived him 4 References Edit HELLMANN K September 1955 Cholinesterase and amine oxidase in the skin a histochemical investigation The Journal of Physiology 129 3 454 63 doi 10 1113 jphysiol 1955 sp005370 PMC 1365976 PMID 13264109 a b c d Kurt Hellman a rare breed of medical and scientific humanitarian Oncology News 13 2 12 14 March April 2018 a b c Eccles Suzanne A Steiner Rudolf K 2012 06 14 Kurt Hellmann D M D Phil Oxon A happy 90th birthday Clinical amp Experimental Metastasis 29 6 523 526 doi 10 1007 s10585 012 9490 4 ISSN 0262 0898 PMID 22695808 metastasis research org In Memoriam Professor Kurt Hellmann metastasis research org Retrieved 2018 07 14 Retrieved from https en wikipedia org w index php title Kurt Hellmann amp oldid 1044149679, wikipedia, wiki, book, books, library,
