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Krukenberg's spindle

Krukenberg's spindle is the name given to the pattern formed on the inner surface of the cornea by pigmented iris cells that are shed during the mechanical rubbing of posterior pigment layer of the iris with the zonules that are deposited as a result of the currents of the aqueous humor. The sign was described in 1899 by Friedrich Ernst Krukenberg (1871-1946), who was a German pathologist specialising in ophthalmology.[1]

Krukenberg's spindle
Slit lamp photograph showing Krukenberg's Spindle as pigment cell deposits on the cornea
SpecialtyOphthalmology

Diagnosis edit

Differential diagnosis edit

Iritis edit

  • Painful red eye with photophobia associated with inflammation

Vortex keratopathy edit

Corneal guttata edit

  • Non-transparent collagen deposits appearing following loss of corneal endothelial cells[3]

See also edit

References edit

  1. ^ Krukenberg F. (1899) Beiderseitige angeborene Melanose der Hornhaut. Klin Mbl Augenheilkd 37:254-258.
  2. ^ Chew, E; Ghosh, M; McCulloch, C (June 1982). "Amiodarone-induced cornea verticillata". Canadian Journal of Ophthalmology. 17 (3): 96–9. PMID 7116220.
  3. ^ Akimune C, Watanabe H, Maeda N, et al. (January 2000). "Corneal guttata associated with the corneal dystrophy resulting from a betaig-h3 R124H mutation". The British Journal of Ophthalmology. 84 (1): 67–71. doi:10.1136/bjo.84.1.67. PMC 1723238. PMID 10611102.

External links edit

krukenberg, spindle, name, given, pattern, formed, inner, surface, cornea, pigmented, iris, cells, that, shed, during, mechanical, rubbing, posterior, pigment, layer, iris, with, zonules, that, deposited, result, currents, aqueous, humor, sign, described, 1899. Krukenberg s spindle is the name given to the pattern formed on the inner surface of the cornea by pigmented iris cells that are shed during the mechanical rubbing of posterior pigment layer of the iris with the zonules that are deposited as a result of the currents of the aqueous humor The sign was described in 1899 by Friedrich Ernst Krukenberg 1871 1946 who was a German pathologist specialising in ophthalmology 1 Krukenberg s spindleSlit lamp photograph showing Krukenberg s Spindle as pigment cell deposits on the corneaSpecialtyOphthalmology Contents 1 Diagnosis 1 1 Differential diagnosis 1 1 1 Iritis 1 1 2 Vortex keratopathy 1 1 3 Corneal guttata 2 See also 3 References 4 External linksDiagnosis editDifferential diagnosis edit Iritis edit Painful red eye with photophobia associated with inflammation Vortex keratopathy edit Corneal deposits also known as cornea verticillata caused by netarsudil eye drops or chronic amiodarone use for cardiac arrhythmias 2 Corneal guttata edit Non transparent collagen deposits appearing following loss of corneal endothelial cells 3 See also editPigment dispersion syndromeReferences edit Krukenberg F 1899 Beiderseitige angeborene Melanose der Hornhaut Klin Mbl Augenheilkd 37 254 258 Chew E Ghosh M McCulloch C June 1982 Amiodarone induced cornea verticillata Canadian Journal of Ophthalmology 17 3 96 9 PMID 7116220 Akimune C Watanabe H Maeda N et al January 2000 Corneal guttata associated with the corneal dystrophy resulting from a betaig h3 R124H mutation The British Journal of Ophthalmology 84 1 67 71 doi 10 1136 bjo 84 1 67 PMC 1723238 PMID 10611102 External links edit Retrieved from https en wikipedia org w index php title Krukenberg 27s spindle amp oldid 1078584431, wikipedia, wiki, book, books, library,

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