Juxtaglomerular cells secrete renin in response to a drop in pressure detected by stretch receptors in the vascular walls, or when stimulated by macula densa cells. Macula densa cells are located in the distal convoluted tubule, and stimulate juxtaglomerular cells to release renin when they detect a drop in chloride concentration in tubular fluid. Together, juxtaglomerular cells, extraglomerular mesangial cells and macula densa cells comprise the juxtaglomerular apparatus.
In appropriately stained tissue sections, juxtaglomerular cells are distinguished by their granulated cytoplasm.
The juxtaglomerular cell is a cell that is located near the glomerulus, hence its name.
Similar to cardiac tissue, juxtaglomerular cells harbor β1 adrenergic receptors. When stimulated by epinephrine or norepinephrine, these receptors induce the secretion of renin. These cells also respond directly to a decrease in systemic blood pressure which is manifested as a lower renal perfusion pressure.
juxtaglomerular, cell, confused, with, granule, cell, this, article, needs, additional, citations, verification, please, help, improve, this, article, adding, citations, reliable, sources, unsourced, material, challenged, removed, find, sources, news, newspape. Not to be confused with granule cell This article needs additional citations for verification Please help improve this article by adding citations to reliable sources Unsourced material may be challenged and removed Find sources Juxtaglomerular cell news newspapers books scholar JSTOR November 2022 Learn how and when to remove this template message Juxtaglomerular cells JG cells also known as juxtaglomerular granular cells are cells in the kidney that synthesize store and secrete the enzyme renin 1 They are specialized smooth muscle cells mainly in the walls of the afferent arterioles and some in the efferent arterioles citation needed that deliver blood to the glomerulus In synthesizing renin they play a critical role in the renin angiotensin system and thus in autoregulation of the kidney Juxtaglomerular cellMicroscopic image of juxtaglomerular cellsDrawing of renal corpuscle showing juxtaglomerular cells macula densa cells and extraglomerular mesangium IdentifiersFMA84138 84138 84138Anatomical terminology edit on Wikidata Juxtaglomerular cells secrete renin in response to a drop in pressure detected by stretch receptors in the vascular walls or when stimulated by macula densa cells Macula densa cells are located in the distal convoluted tubule and stimulate juxtaglomerular cells to release renin when they detect a drop in chloride concentration in tubular fluid Together juxtaglomerular cells extraglomerular mesangial cells and macula densa cells comprise the juxtaglomerular apparatus In appropriately stained tissue sections juxtaglomerular cells are distinguished by their granulated cytoplasm The juxtaglomerular cell is a cell that is located near the glomerulus hence its name Similar to cardiac tissue juxtaglomerular cells harbor b1 adrenergic receptors When stimulated by epinephrine or norepinephrine these receptors induce the secretion of renin These cells also respond directly to a decrease in systemic blood pressure which is manifested as a lower renal perfusion pressure See also editJuxtaglomerular cell tumor Juxtaglomerular apparatus List of distinct cell types in the adult human bodyReferences edit Kopp Ulla C 2011 Neural Control of Renin Secretion Rate Morgan amp Claypool Life Sciences Retrieved 18 November 2022 nbsp This article related to the genitourinary system is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Juxtaglomerular cell amp oldid 1165931999, wikipedia, wiki, book, books, library,
