Brodmann area 8, or BA8, is part of the frontalcortex in the human brain. Situated just anterior to the premotor cortex (BA6), it includes the frontal eye fields (so-named because they are believed to play an important role in the control of eye movements). Damage to this area, by stroke, trauma or infection, causes tonic deviation of the eyes towards the side of the injury. This finding occurs during the first few hours of an acute event such as cerebrovascular infarct (stroke) or hemorrhage (bleeding).
GuenonEdit
The term Brodmann area 8 refers to a cytoarchitecturally defined portion of the frontal lobe of the guenon. Located rostral to the arcuate sulcus, it was not considered by Brodmann-1909 to be topographically homologous to the intermediate frontal area 8 of the human.
Distinctive features (Brodmann-1905): compared to Brodmann area 6-1909, area 8 has a diffuse but clearly present internal granular layer (IV); sublayer 3b of the external pyramidal layer (III) has densely distributed medium-sized pyramidal cells; the internal pyramidal layer (V) has larger ganglion cells densely distributed with some granule cells interspersed; the external granular layer (II) is denser and broader; cell layers are more distinct; the abundance of cells is somewhat greater.[1]
FunctionsEdit
The area is involved in eye movements and possibly in the management of uncertainty. A functional magnetic resonance imaging study demonstrated that Brodmann area 8 activation occurs when test subjects experience uncertainty, and that with increasing uncertainty there is increasing activation.[2]
An alternative interpretation is that this activation in the frontal cortex encodes hope, a higher-order expectation positively correlated with uncertainty.[3]
ImageEdit
Animation.
front view.
Lateral view.
Medial view.
See alsoEdit
Wikimedia Commons has media related to Brodmann area 8.
^ This article incorporates text available under the CC BY 3.0 license. . Archived from the original on December 7, 2013. Retrieved December 3, 2013.{{cite web}}: CS1 maint: bot: original URL status unknown (link)
^Volz KG, Schubotz RI, von Cramon DY (2005). "Variants of uncertainty in decision-making and their neural correlates". Brain Res. Bull. 67 (5): 403–12. doi:10.1016/j.brainresbull.2005.06.011. PMID 16216687. S2CID 15845324.
^Chew and Ho, Hope: An Empirical Study of Attitude toward the Timing of Uncertainty Resolution, J Risk and Uncertainty 8(3):267-288. 1994
October 19, 2023
brodmann, area, brodmann, cytologically, defined, regions, brain, involved, planning, complex, movements, citation, needed, image, brain, with, shown, redimage, brain, with, shown, orangedetailsidentifierslatinarea, frontalis, intermedianeuronames1034neurolex,. Brodmann area 8 is one of Brodmann s cytologically defined regions of the brain It is involved in planning complex movements citation needed Brodmann area 8Image of brain with Brodmann area 8 shown in redImage of brain with Brodmann area 8 shown in orangeDetailsIdentifiersLatinArea frontalis intermediaNeuroNames1034NeuroLex IDbirnlex 1739FMA68605Anatomical terms of neuroanatomy edit on Wikidata Lateral surface of the brain with Brodmann s areas numbered 8 is labeled in upper left Contents 1 Human 2 Guenon 3 Functions 4 Image 5 See also 6 ReferencesHuman EditBrodmann area 8 or BA8 is part of the frontal cortex in the human brain Situated just anterior to the premotor cortex BA6 it includes the frontal eye fields so named because they are believed to play an important role in the control of eye movements Damage to this area by stroke trauma or infection causes tonic deviation of the eyes towards the side of the injury This finding occurs during the first few hours of an acute event such as cerebrovascular infarct stroke or hemorrhage bleeding Guenon EditThe term Brodmann area 8 refers to a cytoarchitecturally defined portion of the frontal lobe of the guenon Located rostral to the arcuate sulcus it was not considered by Brodmann 1909 to be topographically homologous to the intermediate frontal area 8 of the human Distinctive features Brodmann 1905 compared to Brodmann area 6 1909 area 8 has a diffuse but clearly present internal granular layer IV sublayer 3b of the external pyramidal layer III has densely distributed medium sized pyramidal cells the internal pyramidal layer V has larger ganglion cells densely distributed with some granule cells interspersed the external granular layer II is denser and broader cell layers are more distinct the abundance of cells is somewhat greater 1 Functions EditThe area is involved in eye movements and possibly in the management of uncertainty A functional magnetic resonance imaging study demonstrated that Brodmann area 8 activation occurs when test subjects experience uncertainty and that with increasing uncertainty there is increasing activation 2 An alternative interpretation is that this activation in the frontal cortex encodes hope a higher order expectation positively correlated with uncertainty 3 Image Edit nbsp Animation nbsp front view nbsp Lateral view nbsp Medial view See also Edit nbsp Wikimedia Commons has media related to Brodmann area 8 Brodmann area List of regions in the human brainReferences Edit nbsp This article incorporates text available under the CC BY 3 0 license BrainInfo Archived from the original on December 7 2013 Retrieved December 3 2013 a href Template Cite web html title Template Cite web cite web a CS1 maint bot original URL status unknown link Volz KG Schubotz RI von Cramon DY 2005 Variants of uncertainty in decision making and their neural correlates Brain Res Bull 67 5 403 12 doi 10 1016 j brainresbull 2005 06 011 PMID 16216687 S2CID 15845324 Chew and Ho Hope An Empirical Study of Attitude toward the Timing of Uncertainty Resolution J Risk and Uncertainty 8 3 267 288 1994 Retrieved from https en wikipedia org w index php title Brodmann area 8 amp oldid 1172894071, wikipedia, wiki, book, books, library,
