Infectious hypodermal and hematopoietic necrosis (IHHN) is a viral disease of penaeid shrimp that causes mass mortality (up to 90%) among the Western blue shrimp (Penaeus stylirostris) and severe deformations in the Pacific white shrimp (P. vannamei). It occurs in Pacific farmed and wild shrimp, but not in wild shrimp on the Atlantic coast of the Americas. The shrimp-farming industry has developed several broodstocks of both P. stylirostris and P. vannamei that are resistant against IHHN infection.[1]
Infectious hypodermal and hematopoietic necrosis virus
The disease is caused by a single-stranded DNA virus of the species Decapod pestylhamaparvovirus 1, earlier known as IHHN virus, the smallest of the known penaeid shrimp viruses (22 nm).[2]
VirologyEdit
This virus has been classified as Penaeus stylirostris hamaparvovirus. The genome is 4.1 kilobases in length. There are three open reading frames in its genome:[3] a left non structural protein (NS1) of 2001 base pairs (bp), a mid non structural protein (NS2) of 1092 bp and a right capsid protein of 990 bp. NSI appears to be a DNA helicase with ATPase activity.
The mutation rate in the genome has been estimated to be ~1.4 x 10−4 substitutions/site/year.[4] This is considerably higher than the rate in the double stranded DNA viruses and similar to that found in RNA viruses. It is also similar to the rate found in other single stranded DNA viruses.
^Gulf States Marine Fisheries Commission: Non-Native Species Summaries: Infectious Hypodermal and Hematopoietic Necrosis Virus (IHHNV) 2005-05-28 at the Wayback Machine, 2003. Accessed June 30, 2005.
^Rai P, Safeena MP, Karunasagar I, Karunasagar I (2011) Complete nucleic acid sequence of Penaeus stylirostris hamaparvovirus (PstDNV) from India. Virus Res 158(1-2):37-45
^Robles-Sikisaka R, Bohonak AJ, McClenaghan LR Jr, Dhar AK (2010) Genetic signature of rapid IHHNV (infectious hypodermal and hematopoietic necrosis virus) expansion in wild Penaeus shrimp populations. PLoS One 5(7):e11799. Link
infectious, hypodermal, hematopoietic, necrosis, ihhn, viral, disease, penaeid, shrimp, that, causes, mass, mortality, among, western, blue, shrimp, penaeus, stylirostris, severe, deformations, pacific, white, shrimp, vannamei, occurs, pacific, farmed, wild, s. Infectious hypodermal and hematopoietic necrosis IHHN is a viral disease of penaeid shrimp that causes mass mortality up to 90 among the Western blue shrimp Penaeus stylirostris and severe deformations in the Pacific white shrimp P vannamei It occurs in Pacific farmed and wild shrimp but not in wild shrimp on the Atlantic coast of the Americas The shrimp farming industry has developed several broodstocks of both P stylirostris and P vannamei that are resistant against IHHN infection 1 Decapod penstylhamaparvovirus 1Virus classification unranked VirusRealm MonodnaviriaKingdom ShotokuviraePhylum CossaviricotaClass QuintoviricetesOrder PiccoviralesFamily ParvoviridaeGenus PenstylhamaparvovirusSpecies Decapod penstylhamaparvovirus 1SynonymsInfectious hypodermal and hematopoietic necrosis virusThe disease is caused by a single stranded DNA virus of the species Decapod pestylhamaparvovirus 1 earlier known as IHHN virus the smallest of the known penaeid shrimp viruses 22 nm 2 Virology EditThis virus has been classified as Penaeus stylirostris hamaparvovirus The genome is 4 1 kilobases in length There are three open reading frames in its genome 3 a left non structural protein NS1 of 2001 base pairs bp a mid non structural protein NS2 of 1092 bp and a right capsid protein of 990 bp NSI appears to be a DNA helicase with ATPase activity The mutation rate in the genome has been estimated to be 1 4 x 10 4 substitutions site year 4 This is considerably higher than the rate in the double stranded DNA viruses and similar to that found in RNA viruses It is also similar to the rate found in other single stranded DNA viruses References Edit World Organization for Animal Health OIE Aquatic Manual 4th Ed 2003 Section 4 1 6 Archived 2005 03 08 at the Wayback Machine ISBN 92 9044 563 7 Gulf States Marine Fisheries Commission Non Native Species Summaries Infectious Hypodermal and Hematopoietic Necrosis Virus IHHNV Archived 2005 05 28 at the Wayback Machine 2003 Accessed June 30 2005 Rai P Safeena MP Karunasagar I Karunasagar I 2011 Complete nucleic acid sequence of Penaeus stylirostris hamaparvovirus PstDNV from India Virus Res 158 1 2 37 45 Robles Sikisaka R Bohonak AJ McClenaghan LR Jr Dhar AK 2010 Genetic signature of rapid IHHNV infectious hypodermal and hematopoietic necrosis virus expansion in wild Penaeus shrimp populations PLoS One 5 7 e11799 LinkExternal links EditViral zone 1 nbsp This veterinary medicine related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Infectious hypodermal and hematopoietic necrosis amp oldid 1100485997, wikipedia, wiki, book, books, library,
