Human endogenous retrovirus K endopeptidase (EC 3.4.23.50, human endogenous retrovirus K10 endopeptidase, endogenous retrovirus HERV-K10 putative protease, human endogenous retrovirus K retropepsin, HERV K10 endopeptidase, HERV K10 retropepsin, HERV-K PR, HERV-K protease, HERV-K113 protease, human endogenous retrovirus K113 protease, human retrovirus K10 retropepsin) is an enzyme derived from an endogenous retrovirus.[1] This enzyme catalyses the following chemical reaction:
Processing at the authentic HIV-1 PR recognition site and release of the mature p17 matrix and the p24 capsid protein, as a result of the cleavage of the -SQNY-PIVQ- cleavage site.
This enzyme belongs to the peptidase family A2 (retropepsins).
Referencesedit
^Towler EM, Gulnik SV, Bhat TN, Xie D, Gustschina E, Sumpter TR, Robertson N, Jones C, Sauter M, Mueller-Lantzsch N, Debouck C, Erickson JW (December 1998). "Functional characterization of the protease of human endogenous retrovirus, K10: can it complement HIV-1 protease?". Biochemistry. 37 (49): 17137–44. doi:10.1021/bi9818927. PMID 9860826.
External linksedit
Human+endogenous+retrovirus+K+endopeptidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
human, endogenous, retrovirus, endopeptidase, this, article, technical, most, readers, understand, please, help, improve, make, understandable, experts, without, removing, technical, details, june, 2020, learn, when, remove, this, template, message, human, end. This article may be too technical for most readers to understand Please help improve it to make it understandable to non experts without removing the technical details June 2020 Learn how and when to remove this template message Human endogenous retrovirus K endopeptidase EC 3 4 23 50 human endogenous retrovirus K10 endopeptidase endogenous retrovirus HERV K10 putative protease human endogenous retrovirus K retropepsin HERV K10 endopeptidase HERV K10 retropepsin HERV K PR HERV K protease HERV K113 protease human endogenous retrovirus K113 protease human retrovirus K10 retropepsin is an enzyme derived from an endogenous retrovirus 1 This enzyme catalyses the following chemical reaction Human endogenous retrovirus K endopeptidaseIdentifiersEC no 3 4 23 50DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumSearchPMCarticlesPubMedarticlesNCBIproteins Processing at the authentic HIV 1 PR recognition site and release of the mature p17 matrix and the p24 capsid protein as a result of the cleavage of the SQNY PIVQ cleavage site This enzyme belongs to the peptidase family A2 retropepsins References edit Towler EM Gulnik SV Bhat TN Xie D Gustschina E Sumpter TR Robertson N Jones C Sauter M Mueller Lantzsch N Debouck C Erickson JW December 1998 Functional characterization of the protease of human endogenous retrovirus K10 can it complement HIV 1 protease Biochemistry 37 49 17137 44 doi 10 1021 bi9818927 PMID 9860826 External links editHuman endogenous retrovirus K endopeptidase at the U S National Library of Medicine Medical Subject Headings MeSH Portal nbsp Biology Retrieved from https en wikipedia org w index php title Human endogenous retrovirus K endopeptidase amp oldid 1172349930, wikipedia, wiki, book, books, library,
