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Horrilysin

Horrilysin (EC 3.4.24.47, Crotalus horridus metalloendopeptidase, hemorrhagic proteinase IV, Crotalus horridus horridus venom hemorrhagic proteinase) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Horrilysin
Identifiers
EC no.3.4.24.47
CAS no.84056-81-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
Cleavage of only the single bond Ala14-Leu in the insulin B chain, Ser12-Leu in the A chain, and Ile-Gly, Pro-Ala, and Ser-Trp in melittin

This endopeptidase is present in the venom of the timber rattlesnake (Crotalus horridus horridus)

References edit

  1. ^ Civello DJ, Duong HL, Geren CR (February 1983). "Isolation and characterization of a hemorrhagic proteinase from timber rattlesnake venom". Biochemistry. 22 (4): 749–55. doi:10.1021/bi00273a007. PMID 6340728.
  2. ^ Civello DJ, Moran JB, Geren CR (February 1983). "Substrate specificity of a hemorrhagic proteinase from timber rattlesnake venom". Biochemistry. 22 (4): 755–62. doi:10.1021/bi00273a008. PMID 6340729.

External links edit

horrilysin, crotalus, horridus, metalloendopeptidase, hemorrhagic, proteinase, crotalus, horridus, horridus, venom, hemorrhagic, proteinase, enzyme, this, enzyme, catalyses, following, chemical, reactionidentifiersec, 47cas, 84056, 5databasesintenzintenz, view. Horrilysin EC 3 4 24 47 Crotalus horridus metalloendopeptidase hemorrhagic proteinase IV Crotalus horridus horridus venom hemorrhagic proteinase is an enzyme 1 2 This enzyme catalyses the following chemical reactionHorrilysinIdentifiersEC no 3 4 24 47CAS no 84056 81 5DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumSearchPMCarticlesPubMedarticlesNCBIproteins Cleavage of only the single bond Ala14 Leu in the insulin B chain Ser12 Leu in the A chain and Ile Gly Pro Ala and Ser Trp in melittin This endopeptidase is present in the venom of the timber rattlesnake Crotalus horridus horridus References edit Civello DJ Duong HL Geren CR February 1983 Isolation and characterization of a hemorrhagic proteinase from timber rattlesnake venom Biochemistry 22 4 749 55 doi 10 1021 bi00273a007 PMID 6340728 Civello DJ Moran JB Geren CR February 1983 Substrate specificity of a hemorrhagic proteinase from timber rattlesnake venom Biochemistry 22 4 755 62 doi 10 1021 bi00273a008 PMID 6340729 External links editHorrilysin at the U S National Library of Medicine Medical Subject Headings MeSH Portal nbsp Biology Retrieved from https en wikipedia org w index php title Horrilysin amp oldid 1172349895, wikipedia, wiki, book, books, library,

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