HlyE is unrelated to the well characterised pore-forming E. coli hemolysins of the RTX family, haemolysin A.
HlyE is a protein of 34 kDa that is expressed during anaerobic growth of E. coli. Anaerobic expression is controlled by the transcription factor, FNR, such that, upon ingestion and entry into the anaerobic mammalian intestine, HlyE is produced and may then contribute to the colonisation of the host.[1]
Referencesedit
^ abWallace AJ, Stillman TJ, Atkins A, Jamieson SJ, Bullough PA, Green J, Artymiuk PJ (January 2000). "E. coli hemolysin E (HlyE, ClyA, SheA): X-ray crystal structure of the toxin and observation of membrane pores by electron microscopy". Cell. 100 (2): 265–76. doi:10.1016/S0092-8674(00)81564-0. PMID 10660049. S2CID 1793308.
This article incorporates text from the public domain Pfam and InterPro: IPR013057
January 01, 1970
haemolysin, hlye, protein, family, that, consists, several, enterobacterial, haemolysin, hlye, proteins, hemolysin, hlye, novel, pore, forming, toxin, escherichia, coli, salmonella, typhi, shigella, flexneri, hlye, structure, coli, hemolysin, toxin, identifier. Haemolysin E HlyE is a protein family that consists of several enterobacterial haemolysin HlyE proteins Hemolysin E HlyE is a novel pore forming toxin of Escherichia coli Salmonella typhi and Shigella flexneri Haemolysin E HlyE Structure of E coli hemolysin E toxin 1 IdentifiersSymbolHlyEPfamPF06109InterProIPR010356SCOP21qoy SCOPe SUPFAMTCDB1 C 10OPM superfamily198OPM protein2wcdAvailable protein structures Pfam structures ECOD PDBRCSB PDB PDBe PDBjPDBsumstructure summary HlyE is unrelated to the well characterised pore forming E coli hemolysins of the RTX family haemolysin A HlyE is a protein of 34 kDa that is expressed during anaerobic growth of E coli Anaerobic expression is controlled by the transcription factor FNR such that upon ingestion and entry into the anaerobic mammalian intestine HlyE is produced and may then contribute to the colonisation of the host 1 References edit a b Wallace AJ Stillman TJ Atkins A Jamieson SJ Bullough PA Green J Artymiuk PJ January 2000 E coli hemolysin E HlyE ClyA SheA X ray crystal structure of the toxin and observation of membrane pores by electron microscopy Cell 100 2 265 76 doi 10 1016 S0092 8674 00 81564 0 PMID 10660049 S2CID 1793308 This article incorporates text from the public domain Pfam and InterPro IPR013057 Retrieved from https en wikipedia org w index php title Haemolysin E amp oldid 1032324757, wikipedia, wiki, book, books, library,
