5-hydroxytryptamine receptor 3C is a protein that in humans is encoded by the HTR3Cgene.[3][4] The protein encoded by this gene is a subunit of the 5-HT3 receptor.[4]
^ abcGRCh38: Ensembl release 89: ENSG00000178084 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Niesler B, Frank B, Kapeller J, Rappold GA (Jun 2003). "Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E". Gene. 310: 101–11. doi:10.1016/S0378-1119(03)00503-1. PMID 12801637.
^ abPeters JA, Kelley SP, Dunlop JI, Kirkness EF, Hales TG, Lambert JJ (May 2004). "The 5-hydroxytryptamine type 3 (5-HT3) receptor reveals a novel determinant of single-channel conductance". Biochem Soc Trans. 32 (Pt3): 547–52. doi:10.1042/BST0320547. PMID 15157181.
Further readingedit
Karnovsky AM, Gotow LF, McKinley DD, et al. (2003). "A cluster of novel serotonin receptor 3-like genes on human chromosome 3". Gene. 319: 137–48. doi:10.1016/S0378-1119(03)00803-5. PMID 14597179.
Fasching PA, Kollmannsberger B, Strissel PL, et al. (2008). "Polymorphisms in the novel serotonin receptor subunit gene HTR3C show different risks for acute chemotherapy-induced vomiting after anthracycline chemotherapy". J. Cancer Res. Clin. Oncol. 134 (10): 1079–86. doi:10.1007/s00432-008-0387-1. PMID 18389280. S2CID 7504731.
Ward MB, Kotasek D, McKinnon RA (2008). "Investigation of HTR3C mutations for association with 5HT(3) receptor antagonist anti-emetic efficacy". Pharmacogenomics. 9 (8): 1027–33. doi:10.2217/14622416.9.8.1027. PMID 18681779.
htr3c, hydroxytryptamine, receptor, protein, that, humans, encoded, gene, protein, encoded, this, gene, subunit, receptor, identifiersaliases, hydroxytryptamine, receptor, 3cexternal, idsomim, 610121, homologene, 50847, genecards, gene, location, human, chromo. 5 hydroxytryptamine receptor 3C is a protein that in humans is encoded by the HTR3C gene 3 4 The protein encoded by this gene is a subunit of the 5 HT3 receptor 4 HTR3CIdentifiersAliasesHTR3C 5 hydroxytryptamine receptor 3CExternal IDsOMIM 610121 HomoloGene 50847 GeneCards HTR3CGene location Human Chr Chromosome 3 human 1 Band3q27 1Start184 053 047 bp 1 End184 060 673 bp 1 RNA expression patternBgeeHumanMouse ortholog Top expressed inright lungupper lobe of left lungduodenumright lobe of thyroid glandleft lobe of thyroid glandgallbladdermyometriumskin of abdomenheartn aMore reference expression dataBioGPSn aGene ontologyMolecular functionprotein binding extracellular ligand gated ion channel activity serotonin gated cation selective channel activity ion channel activity transmembrane signaling receptor activityCellular componentintegral component of membrane plasma membrane membrane integral component of plasma membrane neuron projection synapseBiological procession transport signal transduction ion transmembrane transport serotonin receptor signaling pathway chemical synaptic transmission regulation of membrane potential nervous system processSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez170572n aEnsemblENSG00000178084n aUniProtQ8WXA8n aRefSeq mRNA NM 130770n aRefSeq protein NP 570126n aLocation UCSC Chr 3 184 05 184 06 Mbn aPubMed search 2 n aWikidataView Edit HumanReferences edit a b c GRCh38 Ensembl release 89 ENSG00000178084 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Niesler B Frank B Kapeller J Rappold GA Jun 2003 Cloning physical mapping and expression analysis of the human 5 HT3 serotonin receptor like genes HTR3C HTR3D and HTR3E Gene 310 101 11 doi 10 1016 S0378 1119 03 00503 1 PMID 12801637 a b Peters JA Kelley SP Dunlop JI Kirkness EF Hales TG Lambert JJ May 2004 The 5 hydroxytryptamine type 3 5 HT3 receptor reveals a novel determinant of single channel conductance Biochem Soc Trans 32 Pt3 547 52 doi 10 1042 BST0320547 PMID 15157181 Further reading editKarnovsky AM Gotow LF McKinley DD et al 2003 A cluster of novel serotonin receptor 3 like genes on human chromosome 3 Gene 319 137 48 doi 10 1016 S0378 1119 03 00803 5 PMID 14597179 Fasching PA Kollmannsberger B Strissel PL et al 2008 Polymorphisms in the novel serotonin receptor subunit gene HTR3C show different risks for acute chemotherapy induced vomiting after anthracycline chemotherapy J Cancer Res Clin Oncol 134 10 1079 86 doi 10 1007 s00432 008 0387 1 PMID 18389280 S2CID 7504731 Ward MB Kotasek D McKinnon RA 2008 Investigation of HTR3C mutations for association with 5HT 3 receptor antagonist anti emetic efficacy Pharmacogenomics 9 8 1027 33 doi 10 2217 14622416 9 8 1027 PMID 18681779 External links editHTR3C protein human at the U S National Library of Medicine Medical Subject Headings MeSH nbsp This transmembrane receptor related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title HTR3C amp oldid 1142697295, wikipedia, wiki, book, books, library,
