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Glycoside hydrolase family 46

In molecular biology, glycoside hydrolase family 46 is a family of glycoside hydrolases.

Glyco_hydro_46
streptomyces n174 chitosanase ph5.5 298k
Identifiers
SymbolGlyco_hydro_46
PfamPF01374
Pfam clanCL0037
InterProIPR000400
SCOP21chk / SCOPe / SUPFAM
CAZyGH46
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families.[1][2][3] This classification is available on the CAZy web site,[4][5] and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.[6][7]

Glycoside hydrolase family 46 CAZY GH_46 comprises enzymes with only one known activity; chitosanase (EC 3.2.1.132). Chitosanase enzymes catalyse the endohydrolysis of beta-1,4-linkages between N-acetyl-D-glucosamine and D-glucosamine residues in a partly acetylated chitosan.

References edit

  1. ^ Henrissat B, Callebaut I, Fabrega S, Lehn P, Mornon JP, Davies G (July 1995). "Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases". Proceedings of the National Academy of Sciences of the United States of America. 92 (15): 7090–4. Bibcode:1995PNAS...92.7090H. doi:10.1073/pnas.92.15.7090. PMC 41477. PMID 7624375.
  2. ^ Davies G, Henrissat B (September 1995). "Structures and mechanisms of glycosyl hydrolases". Structure. 3 (9): 853–9. doi:10.1016/S0969-2126(01)00220-9. PMID 8535779.
  3. ^ Henrissat B, Bairoch A (June 1996). "Updating the sequence-based classification of glycosyl hydrolases". The Biochemical Journal. 316 (Pt 2): 695–6. doi:10.1042/bj3160695. PMC 1217404. PMID 8687420.
  4. ^ "Home". CAZy.org. Retrieved 2018-03-06.
  5. ^ Lombard V, Golaconda Ramulu H, Drula E, Coutinho PM, Henrissat B (January 2014). "The carbohydrate-active enzymes database (CAZy) in 2013". Nucleic Acids Research. 42 (Database issue): D490-5. doi:10.1093/nar/gkt1178. PMC 3965031. PMID 24270786.
  6. ^ "Glycoside Hydrolase Family 46". CAZypedia.org. Retrieved 2018-03-06.
  7. ^ CAZypedia Consortium (December 2018). "Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes" (PDF). Glycobiology. 28 (1): 3–8. doi:10.1093/glycob/cwx089. PMID 29040563.
This article incorporates text from the public domain Pfam and InterPro: IPR000400

glycoside, hydrolase, family, molecular, biology, glycoside, hydrolase, family, family, glycoside, hydrolases, glyco, hydro, 46streptomyces, n174, chitosanase, 298kidentifierssymbolglyco, hydro, 46pfampf01374pfam, clancl0037interproipr000400scop21chk, scope, s. In molecular biology glycoside hydrolase family 46 is a family of glycoside hydrolases Glyco hydro 46streptomyces n174 chitosanase ph5 5 298kIdentifiersSymbolGlyco hydro 46PfamPF01374Pfam clanCL0037InterProIPR000400SCOP21chk SCOPe SUPFAMCAZyGH46Available protein structures Pfam structures ECOD PDBRCSB PDB PDBe PDBjPDBsumstructure summaryGlycoside hydrolases EC 3 2 1 are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates or between a carbohydrate and a non carbohydrate moiety A classification system for glycoside hydrolases based on sequence similarity has led to the definition of gt 100 different families 1 2 3 This classification is available on the CAZy web site 4 5 and also discussed at CAZypedia an online encyclopedia of carbohydrate active enzymes 6 7 Glycoside hydrolase family 46 CAZY GH 46 comprises enzymes with only one known activity chitosanase EC 3 2 1 132 Chitosanase enzymes catalyse the endohydrolysis of beta 1 4 linkages between N acetyl D glucosamine and D glucosamine residues in a partly acetylated chitosan References edit Henrissat B Callebaut I Fabrega S Lehn P Mornon JP Davies G July 1995 Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases Proceedings of the National Academy of Sciences of the United States of America 92 15 7090 4 Bibcode 1995PNAS 92 7090H doi 10 1073 pnas 92 15 7090 PMC 41477 PMID 7624375 Davies G Henrissat B September 1995 Structures and mechanisms of glycosyl hydrolases Structure 3 9 853 9 doi 10 1016 S0969 2126 01 00220 9 PMID 8535779 Henrissat B Bairoch A June 1996 Updating the sequence based classification of glycosyl hydrolases The Biochemical Journal 316 Pt 2 695 6 doi 10 1042 bj3160695 PMC 1217404 PMID 8687420 Home CAZy org Retrieved 2018 03 06 Lombard V Golaconda Ramulu H Drula E Coutinho PM Henrissat B January 2014 The carbohydrate active enzymes database CAZy in 2013 Nucleic Acids Research 42 Database issue D490 5 doi 10 1093 nar gkt1178 PMC 3965031 PMID 24270786 Glycoside Hydrolase Family 46 CAZypedia org Retrieved 2018 03 06 CAZypedia Consortium December 2018 Ten years of CAZypedia a living encyclopedia of carbohydrate active enzymes PDF Glycobiology 28 1 3 8 doi 10 1093 glycob cwx089 PMID 29040563 This article incorporates text from the public domain Pfam and InterPro IPR000400 Portal nbsp Biology Retrieved from https en wikipedia org w index php title Glycoside hydrolase family 46 amp oldid 1169067147, wikipedia, wiki, book, books, library,

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