This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is glycerol hydro-lyase (3-hydroxypropanol-forming). Other names in common use include glycerol dehydrase, and glycerol hydro-lyase. This enzyme participates in glycerolipid metabolism. It employs one cofactor, cobalamin.
Structural studiesedit
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1IWP and 1MMF.
Referencesedit
Forage RG, Foster MA (1982). "Glycerol fermentation in Klebsiella pneumoniae: functions of the coenzyme B12-dependent glycerol and diol dehydratases". J. Bacteriol. 149 (2): 413–9. doi:10.1128/JB.149.2.413-419.1982. PMC216523. PMID 7035429.
Schneider Z, Larsen EG, Jacobson G, Johnson BC, Pawelkiewicz J (1970). "Purification and properties of glycerol dehydrase". J. Biol. Chem. 245 (13): 3388–96. PMID 4989992.
Schneider Z, Pawelkiewicz J (1966). "The properties of glycerol dehydratase isolated from Aerobacter aerogenes, and the properties of the apoenzyme subunits". Acta Biochim. Pol. 13 (4): 311–28. PMID 5962440.
SMILEY KL, SOBOLOV M (1962). "A cobamide-requiring glycerol dehydrase from an acrolein-forming Lactobacillus". Arch. Biochem. Biophys. 97 (3): 538–43. doi:10.1016/0003-9861(62)90118-2. PMID 14039344.
glycerol, dehydratase, enzymology, glycerol, dehydratase, catalyzes, chemical, reactionglycerol, dehydrataseidentifiersec, 30cas, 9077, 3databasesintenzintenz, viewbrendabrenda, entryexpasynicezyme, viewkeggkegg, entrymetacycmetabolic, pathwaypriamprofilepdb, . In enzymology a glycerol dehydratase EC 4 2 1 30 catalyzes the chemical reactionglycerol dehydrataseIdentifiersEC no 4 2 1 30CAS no 9077 68 3DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumGene OntologyAmiGO QuickGOSearchPMCarticlesPubMedarticlesNCBIproteins glycerol displaystyle rightleftharpoons 3 hydroxypropanal H2OThis enzyme belongs to the family of lyases specifically the hydro lyases which cleave carbon oxygen bonds The systematic name of this enzyme class is glycerol hydro lyase 3 hydroxypropanol forming Other names in common use include glycerol dehydrase and glycerol hydro lyase This enzyme participates in glycerolipid metabolism It employs one cofactor cobalamin Structural studies editAs of late 2007 two structures have been solved for this class of enzymes with PDB accession codes 1IWP and 1MMF References editForage RG Foster MA 1982 Glycerol fermentation in Klebsiella pneumoniae functions of the coenzyme B12 dependent glycerol and diol dehydratases J Bacteriol 149 2 413 9 doi 10 1128 JB 149 2 413 419 1982 PMC 216523 PMID 7035429 Schneider Z Larsen EG Jacobson G Johnson BC Pawelkiewicz J 1970 Purification and properties of glycerol dehydrase J Biol Chem 245 13 3388 96 PMID 4989992 Schneider Z Pawelkiewicz J 1966 The properties of glycerol dehydratase isolated from Aerobacter aerogenes and the properties of the apoenzyme subunits Acta Biochim Pol 13 4 311 28 PMID 5962440 SMILEY KL SOBOLOV M 1962 A cobamide requiring glycerol dehydrase from an acrolein forming Lactobacillus Arch Biochem Biophys 97 3 538 43 doi 10 1016 0003 9861 62 90118 2 PMID 14039344 Portal nbsp Biology This EC 4 2 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Glycerol dehydratase amp oldid 1172348773, wikipedia, wiki, book, books, library,
