Following a suggestion by Jöns Jacob Berzelius, Mulder used the term protein in his 1838 paper, "On the composition of some animal substances" (originally in French but translated in 1839 to German). In the same publication, he also proposed that animals draw most of their protein from plants.[3][4][5]
Mulder "was the first to propose a theory concerning the causes of the differences between albumin, casein, and fibrin, and other substances more or less similar to them in physical properties and in their chemical behavior when exposed to reagents. Analyses of these substances showed that their percentage contribution with respect to carbon, hydrogen, nitrogen and oxygen were so similar as to suggest that they contain one common radical."[6] This radical, a macromolecule, had formula and was known as protein. The variations in albuminous substances were attributed to peripheral bonds of protein to sulfur and/or phosphorus. Justus Liebig and his students sought to determine the structure of proteins, but until the methods of Emil Fischer and Franz Hofmeister became available, the amino acid decompositions were unknown.[7]
^ ab"Prof.dr. G.J. Mulder (1802–1880)". Catalogus Professorum Academiæ Rheno-Traiectinæ (in Dutch). Utrecht University. Retrieved 10 June 2021.
^Wels, C. B. (12 November 2013) [First published 1985]. "Mulder, Gerardus Johannis (1802–1880)". Biografisch Woordenboek van Nederland (in Dutch). The Hague.{{cite encyclopedia}}: CS1 maint: location missing publisher (link)
^Bulletin des Sciences Physiques et Naturelles en Néerlande (1838). pg 104. SUR LA COMPOSITION DE QUELQUES SUBSTANCES ANIMALES
^Hartley, Harold (1951). "Origin of the Word 'Protein.'". Nature. 168 (4267): 244. Bibcode:1951Natur.168..244H. doi:10.1038/168244a0. PMID 14875059. S2CID 4271525.
^"Ueber die Zusammensetzung einiger thierischen Substanzen". Journal für Praktische Chemie (in German). 16: 129–152. 1838. doi:10.1002/prac.18390160137.
^Elmer McCollum (1957) A History of Nutrition, chapter 4: Knowledge of Albuminous Substances, page 48 "The studies of Mulder on albuminous substances", Houghton-Mifflin
Ihde, Aaron (1964) The Development of Modern Chemistry, Harper and Row, pages 359 and 423–424.
External linksedit
On the composition of some animal substances Translation of parts of Mulder's article from: Mikulás Teich, A Documentary History of Biochemistry, 1770-1940 (Rutherford, NJ: Fairleigh Dickinson University Press, 1992) "Ueber die Zusammensetzung einiger thierischen Substanzen". Journal für Praktische Chemie (in German). 16: 129–152. 1839. doi:10.1002/prac.18390160137.
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gerardus, johannes, mulder, this, article, needs, additional, citations, verification, please, help, improve, this, article, adding, citations, reliable, sources, unsourced, material, challenged, removed, find, sources, news, newspapers, books, scholar, jstor,. This article needs additional citations for verification Please help improve this article by adding citations to reliable sources Unsourced material may be challenged and removed Find sources Gerardus Johannes Mulder news newspapers books scholar JSTOR February 2015 Learn how and when to remove this template message Gerardus Johannes Mulder or Gerrit Jan Mulder 27 December 1802 18 April 1880 was a Dutch organic and analytical chemist Gerardus Johannes MulderBorn 1802 12 27 27 December 1802UtrechtDied18 April 1880 1880 04 18 aged 77 BennekomAlma materUtrecht UniversityKnown forProteinSpouseWilhelmina van Rossem m 1827 wbr Children6 including EduardScientific careerFieldsChemistryInstitutionsUtrecht UniversityThesisDissertatio medica de opio ejusque principiis actione inter se comparatis 1825 Doctoral advisorNicolaas Cornelis de FremeryDoctoral studentsHendrik Cornelis Dibbits Nicolaas Wilhelm Pieter RauwenhoffGerardus Johannes Mulder Contents 1 Life 1 1 Protein 2 References 3 External linksLife editMulder was born in Utrecht and earned a medical degree from Utrecht University 1 He became a reader of chemistry in Rotterdam 2 and in 1840 he was appointed professor at Utrecht University 1 Protein edit Following a suggestion by Jons Jacob Berzelius Mulder used the term protein in his 1838 paper On the composition of some animal substances originally in French but translated in 1839 to German In the same publication he also proposed that animals draw most of their protein from plants 3 4 5 Mulder was the first to propose a theory concerning the causes of the differences between albumin casein and fibrin and other substances more or less similar to them in physical properties and in their chemical behavior when exposed to reagents Analyses of these substances showed that their percentage contribution with respect to carbon hydrogen nitrogen and oxygen were so similar as to suggest that they contain one common radical 6 This radical a macromolecule had formula C 20 H 31 N 5 O 12 displaystyle ce C20 H31 N5 O12 nbsp and was known as protein The variations in albuminous substances were attributed to peripheral bonds of protein to sulfur and or phosphorus Justus Liebig and his students sought to determine the structure of proteins but until the methods of Emil Fischer and Franz Hofmeister became available the amino acid decompositions were unknown 7 Augustus Voelcker was Mulder s assistant for a year from 1846 8 9 In 1850 Mulder was elected a foreign member of the Royal Swedish Academy of Sciences He died in Bennekom References edit a b Prof dr G J Mulder 1802 1880 Catalogus Professorum Academiae Rheno Traiectinae in Dutch Utrecht University Retrieved 10 June 2021 Wels C B 12 November 2013 First published 1985 Mulder Gerardus Johannis 1802 1880 Biografisch Woordenboek van Nederland in Dutch The Hague a href Template Cite encyclopedia html title Template Cite encyclopedia cite encyclopedia a CS1 maint location missing publisher link Bulletin des Sciences Physiques et Naturelles en Neerlande 1838 pg 104 SUR LA COMPOSITION DE QUELQUES SUBSTANCES ANIMALES Hartley Harold 1951 Origin of the Word Protein Nature 168 4267 244 Bibcode 1951Natur 168 244H doi 10 1038 168244a0 PMID 14875059 S2CID 4271525 Ueber die Zusammensetzung einiger thierischen Substanzen Journal fur Praktische Chemie in German 16 129 152 1838 doi 10 1002 prac 18390160137 Elmer McCollum 1957 A History of Nutrition chapter 4 Knowledge of Albuminous Substances page 48 The studies of Mulder on albuminous substances Houghton Mifflin Hubert Bradford Vickery 1942 Liebig and the Proteins Journal of Chemical Education doi 10 1021 ed019p73 Clarke Ernest 1899 Voelcker John Christopher Augustus In Lee Sidney ed Dictionary of National Biography Vol 58 London Smith Elder amp Co doi 10 1093 odnb 9780192683120 013 28345 Goddard Nicholas 10 December 2020 First published in print and online 23 September 2004 Voelcker John Christopher Augustus Oxford Dictionary of National Biography Oxford University Press doi 10 1093 ref odnb 28345 Ihde Aaron 1964 The Development of Modern Chemistry Harper and Row pages 359 and 423 424 External links editOn the composition of some animal substances Translation of parts of Mulder s article from Mikulas Teich A Documentary History of Biochemistry 1770 1940 Rutherford NJ Fairleigh Dickinson University Press 1992 Ueber die Zusammensetzung einiger thierischen Substanzen Journal fur Praktische Chemie in German 16 129 152 1839 doi 10 1002 prac 18390160137 nbsp nbsp nbsp This article about a Dutch scientist is a stub You can help Wikipedia by expanding it vte nbsp This article about a biochemist is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Gerardus Johannes Mulder amp oldid 1166844794, wikipedia, wiki, book, books, library,
