Wikipedia
Gamma-muurolene synthase
γ-Muurolene synthase (EC 4.2.3.126, Cop3) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lase (cyclizing, γ-muurolene-forming).[1][2] This enzyme catalyses the following chemical reaction
| γ-muurolene synthase | |
|---|---|
| Identifiers | |
| EC no. | 4.2.3.126 |
| Databases | |
| IntEnz | IntEnz view |
| BRENDA | BRENDA entry |
| ExPASy | NiceZyme view |
| KEGG | KEGG entry |
| MetaCyc | metabolic pathway |
| PRIAM | profile |
| PDB structures | RCSB PDB PDBe PDBsum |
- (2E,6E)-farnesyl diphosphate γ-muurolene + diphosphate
The enzyme has been characterized from the fungus Coprinus cinereus.
References edit
- ^ Agger S, Lopez-Gallego F, Schmidt-Dannert C (June 2009). "Diversity of sesquiterpene synthases in the basidiomycete Coprinus cinereus". Molecular Microbiology. 72 (5): 1181–95. doi:10.1111/j.1365-2958.2009.06717.x. PMC 2723806. PMID 19400802.
- ^ López-Gallego F, Wawrzyn GT, Schmidt-Dannert C (December 2010). "Selectivity of fungal sesquiterpene synthases: role of the active site's H-1α loop in catalysis". Applied and Environmental Microbiology. 76 (23): 7723–33. doi:10.1128/aem.01811-10. PMC 2988597. PMID 20889795.
External links edit
- Gamma-muurolene+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)