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Frontal eye fields

January 01, 1970

The frontal eye fields (FEF) are a region located in the frontal cortex, more specifically in Brodmann area 8 or BA8,[1] of the primate brain. In humans, it can be more accurately said to lie in a region around the intersection of the middle frontal gyrus with the precentral gyrus, consisting of a frontal and parietal portion.[2] The FEF is responsible for saccadic eye movements for the purpose of visual field perception and awareness, as well as for voluntary eye movement. The FEF communicates with extraocular muscles indirectly via the paramedian pontine reticular formation. Destruction of the FEF causes deviation of the eyes to the ipsilateral side.

Frontal eye field
Frontal eye field is roughly located between regions #4, #6, and #8
Details
Part ofFrontal cortex
SystemVisual system
Anatomical terms of neuroanatomy
[edit on Wikidata]
Brodmann area 8

Function edit

The cortical area called frontal eye field (FEF) plays an important role in the control of visual attention and eye movements.[3] Electrical stimulation in the FEF elicits saccadic eye movements. The FEF have a topographic structure and represents saccade targets in retinotopic coordinates.[4]

The frontal eye field is reported to be activated during the initiation of eye movements, such as voluntary saccades[5] and pursuit eye movements.[6] There is also evidence that it plays a role in purely sensory processing and that it belongs to a “fast brain” system through a superior colliculus – medial dorsal nucleus – FEF ascending pathway.[7]

In humans, its earliest activations in regard to visual stimuli occur at 45 ms with activations related to changes in visual stimuli within 45–60 ms (these are comparable with response times in the primary visual cortex).[7] This fast brain pathway also provides auditory input at even shorter times starting at 24 ms and being affected by auditory characteristics at 30–60 ms.[7]

The FEF constitutes together with the supplementary eye fields (SEF), the intraparietal sulcus (IPS) and the superior colliculus (SC) one of the most important brain areas involved in the generation and control of eye movements, particularly in the direction contralateral to the frontal eye fields' location. In addition, FEF has an important role in the covert allocation of spatial attention through its reciprocal connectivity with visual cortex.[8]

Clinical significance edit

Lesions edit

Unilateral irritative stimulation of a FEF, such as a frontal seizure causes conjugate gaze contralateral to the stimulation. Conversely, a unilateral destructive lesion of the FEF causes conjugate gaze towards the lesion.

See also edit

This article uses anatomical terminology.

References edit

  1. ^ "Frontal Eye Field--Scholarpedia".
  2. ^ Vernet, M.; Quentin, R.; Chanes, L.; Mitsumasu, A.; Valero-Cabré, A. (2014). "Frontal eye field, where art thou? Anatomy, function, and non-invasive manipulation of frontal regions. involved in eye movements and associated cognitive operations". Frontiers in Integrative Neuroscience. 8: 66. doi:10.3389/fnint.2014.00088. PMC 4141567. PMID 25202241.
  3. ^ Schall, J. D. (2004). "On the role of frontal eye field in guiding attention and saccades". Vision Research. 44 (12): 1453–67. doi:10.1016/j.visres.2003.10.025. PMID 15066404. S2CID 12397479.
  4. ^ Bruce, C. J.; Goldberg, M. E.; Bushnell, M. C.; Stanton, G. B. (1985). "Primate frontal eye fields. II. Physiological and anatomical correlates of electrically evoked eye movements". Journal of Neurophysiology. 54 (3): 714–34. doi:10.1152/jn.1985.54.3.714. PMID 4045546.
  5. ^ . Archived from the original on 2011-11-09.
  6. ^ Mustari MJ, Ono S, Das VE (May 2009). "Signal processing and distribution in cortical-brainstem pathways for smooth pursuit eye movements". Ann. N. Y. Acad. Sci. 1164 (1): 147–54. Bibcode:2009NYASA1164..147M. doi:10.1111/j.1749-6632.2009.03859.x. PMC 3057571. PMID 19645893.
  7. ^ a b c Kirchner, H; Barbeau, E. J.; Thorpe, S. J.; Régis, J; Liégeois-Chauvel, C (2009). "Ultra-rapid sensory responses in the human frontal eye field region". Journal of Neuroscience. 29 (23): 7599–606. doi:10.1523/JNEUROSCI.1233-09.2009. PMC 6665413. PMID 19515928.
  8. ^ Bedini, Marco; Baldauf, Daniel (2021). "Structure, function and connectivity fingerprints of the frontal eye field versus the inferior frontal junction: A comprehensive comparison". European Journal of Neuroscience. 54 (4): 5462–5506. doi:10.1111/ejn.15393. ISSN 1460-9568. PMC 9291791. PMID 34273134.

External links edit

 
Wikimedia Commons has media related to Frontal eye field.
  • Frontal Eye Field (Scholarpedia)

January 01, 1970
frontal, fields, frontal, fields, region, located, frontal, cortex, more, specifically, brodmann, area, primate, brain, humans, more, accurately, said, region, around, intersection, middle, frontal, gyrus, with, precentral, gyrus, consisting, frontal, parietal. The frontal eye fields FEF are a region located in the frontal cortex more specifically in Brodmann area 8 or BA8 1 of the primate brain In humans it can be more accurately said to lie in a region around the intersection of the middle frontal gyrus with the precentral gyrus consisting of a frontal and parietal portion 2 The FEF is responsible for saccadic eye movements for the purpose of visual field perception and awareness as well as for voluntary eye movement The FEF communicates with extraocular muscles indirectly via the paramedian pontine reticular formation Destruction of the FEF causes deviation of the eyes to the ipsilateral side Frontal eye fieldFrontal eye field is roughly located between regions 4 6 and 8DetailsPart ofFrontal cortexSystemVisual systemAnatomical terms of neuroanatomy edit on Wikidata Brodmann area 8 Contents 1 Function 2 Clinical significance 2 1 Lesions 3 See also 4 References 5 External linksFunction editThe cortical area called frontal eye field FEF plays an important role in the control of visual attention and eye movements 3 Electrical stimulation in the FEF elicits saccadic eye movements The FEF have a topographic structure and represents saccade targets in retinotopic coordinates 4 The frontal eye field is reported to be activated during the initiation of eye movements such as voluntary saccades 5 and pursuit eye movements 6 There is also evidence that it plays a role in purely sensory processing and that it belongs to a fast brain system through a superior colliculus medial dorsal nucleus FEF ascending pathway 7 In humans its earliest activations in regard to visual stimuli occur at 45 ms with activations related to changes in visual stimuli within 45 60 ms these are comparable with response times in the primary visual cortex 7 This fast brain pathway also provides auditory input at even shorter times starting at 24 ms and being affected by auditory characteristics at 30 60 ms 7 The FEF constitutes together with the supplementary eye fields SEF the intraparietal sulcus IPS and the superior colliculus SC one of the most important brain areas involved in the generation and control of eye movements particularly in the direction contralateral to the frontal eye fields location In addition FEF has an important role in the covert allocation of spatial attention through its reciprocal connectivity with visual cortex 8 Clinical significance editLesions edit Unilateral irritative stimulation of a FEF such as a frontal seizure causes conjugate gaze contralateral to the stimulation Conversely a unilateral destructive lesion of the FEF causes conjugate gaze towards the lesion See also editThis article uses anatomical terminology Saccade Smooth pursuit Supplementary eye fields IPS LIPReferences edit Frontal Eye Field Scholarpedia Vernet M Quentin R Chanes L Mitsumasu A Valero Cabre A 2014 Frontal eye field where art thou Anatomy function and non invasive manipulation of frontal regions involved in eye movements and associated cognitive operations Frontiers in Integrative Neuroscience 8 66 doi 10 3389 fnint 2014 00088 PMC 4141567 PMID 25202241 Schall J D 2004 On the role of frontal eye field in guiding attention and saccades Vision Research 44 12 1453 67 doi 10 1016 j visres 2003 10 025 PMID 15066404 S2CID 12397479 Bruce C J Goldberg M E Bushnell M C Stanton G B 1985 Primate frontal eye fields II Physiological and anatomical correlates of electrically evoked eye movements Journal of Neurophysiology 54 3 714 34 doi 10 1152 jn 1985 54 3 714 PMID 4045546 Medical Neurosciences Archived from the original on 2011 11 09 Mustari MJ Ono S Das VE May 2009 Signal processing and distribution in cortical brainstem pathways for smooth pursuit eye movements Ann N Y Acad Sci 1164 1 147 54 Bibcode 2009NYASA1164 147M doi 10 1111 j 1749 6632 2009 03859 x PMC 3057571 PMID 19645893 a b c Kirchner H Barbeau E J Thorpe S J Regis J Liegeois Chauvel C 2009 Ultra rapid sensory responses in the human frontal eye field region Journal of Neuroscience 29 23 7599 606 doi 10 1523 JNEUROSCI 1233 09 2009 PMC 6665413 PMID 19515928 Bedini Marco Baldauf Daniel 2021 Structure function and connectivity fingerprints of the frontal eye field versus the inferior frontal junction A comprehensive comparison European Journal of Neuroscience 54 4 5462 5506 doi 10 1111 ejn 15393 ISSN 1460 9568 PMC 9291791 PMID 34273134 External links edit nbsp Wikimedia Commons has media related to Frontal eye field Frontal Eye Field Scholarpedia Retrieved from https en wikipedia org w index php title Frontal eye fields amp oldid 1143574323, wikipedia, wiki, book, books, library,

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