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Carl Friedländer

Carl Friedländer (19 November 1847, Brieg (Brzeg), Silesia – 13 May 1887, Meran (Merano), County of Tyrol) was a German pathologist and microbiologist who helped discover the bacterial cause of pneumonia in 1882.[1] He also first described thromboangiitis obliterans.[2]

Edwin Klebs had seen bacteria in the airways of individuals who died from pneumonia in 1875; however, it was not until 1882 when Friedländer recognized that bacteria (Klebsiella pneumoniae) were nearly always observable in persons dying from pneumonia that the bold statement was made that these were the likely cause of pneumonia. Friedländer's second communication on the micrococci of pneumonia, which appeared on 15 November 1883, touched off a controversy over the causative agent of pneumonia that continued for the next three years. In this second report he noted that he had examined more than 50 additional cases of pneumonia and that he had identified bacteria in nearly all of them and that sections from which the bacteria were absent were from the lungs of patients dying late in the course of the disease. Friedländer also noted that it was necessary to use special stains (e.g. the Gram Stain)[3] to see the bacteria because using ordinary stains (H&E) nuclei and fibrin stained the same way as bacteria and thus obscured the ability to see the bacteria.[4] As a result, Klebsiella pneumoniae is often called Friedländer's bacterium or Friedländer's bacillus.[5] It is unclear if the bacteria that he observed in persons dying of pneumonia were truly all Klebsiella, some may well have been Streptococcus pneumoniae.

In 1886, he introduced the ampoule in medicine.

He died a premature death, aged 39 or 40, after a brief stint with a respiratory disease, believed to be caused by his discovered infectious organism, the Friedlander's Bacillus.

Works edit

  • Friedländer, C. Über die Schizomyceten bei der acuten fibrösen Pneumonie. Virchow's Arch pathol. Anat. u. Physiol., 87 (2):319-324, Feb. 4, 1882.
  • Carl Friedländer: Arteriitis obliterans. Zentralblatt für die medizinischen Wissenschaften, Berlin, 1876, 14.

References edit

  1. ^ Friedländer, C. 1882 Ueber die Schizomyceten bei der acuten fibrösen Pneumonie. Virchow's Arch. pathol. Anat. u. Physiol.,87 (2): 319-324, Feb. 4.
  2. ^ Carl Friedländer: Arteriitis obliterans. Zentralblatt für die medizinischen Wissenschaften, Berlin, 1876, 14
  3. ^ Austrian, R. (1960). "The Gram stain and the etiology of lobar pneumonia, an historical note". Bacteriological Reviews. 24 (3): 261–265. doi:10.1128/BR.24.3.261-265.1960. PMC 441053. PMID 13685217.
  4. ^ Friedländer, C. 1883 Die Mikrokokken der Pneumonie. Fortschr. Med., 1 (22):715-733, Nov. 15.
  5. ^ Kohler, W. & Mochmann, H. (1987): Carl Friedländer (1847–1887) and the discovery of the Pneumococcus—in memory of the centenary of his death. Zeitschrift für ärztliche Fortbildung 81(12):615-618


carl, friedländer, help, expand, this, article, with, text, translated, from, corresponding, article, german, december, 2009, click, show, important, translation, instructions, view, machine, translated, version, german, article, machine, translation, like, de. You can help expand this article with text translated from the corresponding article in German December 2009 Click show for important translation instructions View a machine translated version of the German article Machine translation like DeepL or Google Translate is a useful starting point for translations but translators must revise errors as necessary and confirm that the translation is accurate rather than simply copy pasting machine translated text into the English Wikipedia Consider adding a topic to this template there are already 8 916 articles in the main category and specifying topic will aid in categorization Do not translate text that appears unreliable or low quality If possible verify the text with references provided in the foreign language article You must provide copyright attribution in the edit summary accompanying your translation by providing an interlanguage link to the source of your translation A model attribution edit summary is Content in this edit is translated from the existing German Wikipedia article at de Carl Friedlander see its history for attribution You should also add the template Translated de Carl Friedlander to the talk page For more guidance see Wikipedia Translation Carl Friedlander 19 November 1847 Brieg Brzeg Silesia 13 May 1887 Meran Merano County of Tyrol was a German pathologist and microbiologist who helped discover the bacterial cause of pneumonia in 1882 1 He also first described thromboangiitis obliterans 2 Edwin Klebs had seen bacteria in the airways of individuals who died from pneumonia in 1875 however it was not until 1882 when Friedlander recognized that bacteria Klebsiella pneumoniae were nearly always observable in persons dying from pneumonia that the bold statement was made that these were the likely cause of pneumonia Friedlander s second communication on the micrococci of pneumonia which appeared on 15 November 1883 touched off a controversy over the causative agent of pneumonia that continued for the next three years In this second report he noted that he had examined more than 50 additional cases of pneumonia and that he had identified bacteria in nearly all of them and that sections from which the bacteria were absent were from the lungs of patients dying late in the course of the disease Friedlander also noted that it was necessary to use special stains e g the Gram Stain 3 to see the bacteria because using ordinary stains H amp E nuclei and fibrin stained the same way as bacteria and thus obscured the ability to see the bacteria 4 As a result Klebsiella pneumoniae is often called Friedlander s bacterium or Friedlander s bacillus 5 It is unclear if the bacteria that he observed in persons dying of pneumonia were truly all Klebsiella some may well have been Streptococcus pneumoniae In 1886 he introduced the ampoule in medicine He died a premature death aged 39 or 40 after a brief stint with a respiratory disease believed to be caused by his discovered infectious organism the Friedlander s Bacillus Works editFriedlander C Uber die Schizomyceten bei der acuten fibrosen Pneumonie Virchow s Arch pathol Anat u Physiol 87 2 319 324 Feb 4 1882 Carl Friedlander Arteriitis obliterans Zentralblatt fur die medizinischen Wissenschaften Berlin 1876 14 References edit Friedlander C 1882 Ueber die Schizomyceten bei der acuten fibrosen Pneumonie Virchow s Arch pathol Anat u Physiol 87 2 319 324 Feb 4 Carl Friedlander Arteriitis obliterans Zentralblatt fur die medizinischen Wissenschaften Berlin 1876 14 Austrian R 1960 The Gram stain and the etiology of lobar pneumonia an historical note Bacteriological Reviews 24 3 261 265 doi 10 1128 BR 24 3 261 265 1960 PMC 441053 PMID 13685217 Friedlander C 1883 Die Mikrokokken der Pneumonie Fortschr Med 1 22 715 733 Nov 15 Kohler W amp Mochmann H 1987 Carl Friedlander 1847 1887 and the discovery of the Pneumococcus in memory of the centenary of his death Zeitschrift fur arztliche Fortbildung 81 12 615 618 nbsp nbsp nbsp This article about a German person in the field of medicine is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Carl Friedlander amp oldid 1183694270, wikipedia, wiki, book, books, library,

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