An enzyme inducer is a type of drug that increases the metabolic activity of an enzyme either by binding to the enzyme and activating it, or by increasing the expression of the gene coding for the enzyme.[1][page needed] It is the opposite of an enzyme repressor. There are specific types of enzyme inducers [2] that create cytoprotective pathways that play a role in prevention and treatment of cancer and other diseases including cardiovascular disease and neurodegenerative diseases. Enzyme inducers can be either naturally occurring or synthetically made.
^Stanbury PF, Whitaker A, Hall SJ (2013). Principles of Fermentation Technology (2nd ed.). Elsevier. ISBN9781483292915. Retrieved 1 August 2016.
^Dinkova-Kostova, Albena T (2010). "Exceptionally Potent Inducer of Cytoprotective Enzymes: ELUCIDATION OF THE STRUCTURAL FEATURES THAT DETERMINE INDUCER POTENCY AND REACTIVITY WITH Keap1". The Journal of Biological Chemistry. 285 (44): 33747–33755. doi:10.1074/jbc.M110.163485. PMC2962473. PMID 20801881.
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Hepatic enzyme inducers
Hepatic enzyme inhibitors
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