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Wikipedia

Elliptocyte

Elliptocytes, also known as ovalocytes or cigar cells, are abnormally shaped red blood cells that appear oval or elongated, from slightly egg-shaped to rod or pencil forms. They have normal central pallor with the hemoglobin appearing concentrated at the ends of the elongated cells when viewed through a light microscope. The ends of the cells are blunt and not sharp like sickle cells.[1]

Cigar cells in elliptocytosis
Blood smear showing elliptocytes
SpecialtyHematology
blood film in a patient with hereditary elliptocytosis: approximately 60% to 70% of the RBCs are elliptocytes.
Elliptocyte compared to other forms of poikilocytosis.

Elliptocytes are commonly associated with hereditary elliptocytosis. However, they may also be seen in iron deficiency anemia, sepsis, malaria and other pathological states that decrease red blood cell turnover and or production.[2] In the case of iron deficiency anemia, microcytosis and hypochromia would also be expected.[3]

Causes

Rare elliptocytes (less than 1%) on a peripheral blood smear are a normal finding.[citation needed]

These abnormal red blood cells are seen in higher numbers in the blood films of patients with blood disorders such as:[4]

References

  1. ^ "Ovalocytes/Elliptocytes - LabCE.com, Laboratory Continuing Education". www.labce.com. Retrieved 21 May 2018.
  2. ^ Clinical hematology and oncology : presentation, diagnosis, and treatment. Bruce Furie. Philadelphia, Pa.: Churchill Livingstone. 2003. pp. 276–278. ISBN 0-443-06556-X. OCLC 51582525.{{cite book}}: CS1 maint: others (link)
  3. ^ Robbins & Cotran pathologic basis of disease. Vinay Kumar, Abul K. Abbas, Jon C. Aster, James A. Perkins (10th ed.). Philadelphia, PA. 2021. ISBN 978-0-323-53113-9. OCLC 1191840836.{{cite book}}: CS1 maint: location missing publisher (link) CS1 maint: others (link)
  4. ^ Hirschmann, Douglas C. Tkachuk (2007). Wintrobe's atlas of clinical hematology. Philadelphia, PA [etc.]: Lippincott Williams & Wilkins. ISBN 978-0781770231.


elliptocyte, also, known, ovalocytes, cigar, cells, abnormally, shaped, blood, cells, that, appear, oval, elongated, from, slightly, shaped, pencil, forms, they, have, normal, central, pallor, with, hemoglobin, appearing, concentrated, ends, elongated, cells, . Elliptocytes also known as ovalocytes or cigar cells are abnormally shaped red blood cells that appear oval or elongated from slightly egg shaped to rod or pencil forms They have normal central pallor with the hemoglobin appearing concentrated at the ends of the elongated cells when viewed through a light microscope The ends of the cells are blunt and not sharp like sickle cells 1 Cigar cells in elliptocytosisBlood smear showing elliptocytesSpecialtyHematologyblood film in a patient with hereditary elliptocytosis approximately 60 to 70 of the RBCs are elliptocytes Elliptocyte compared to other forms of poikilocytosis Elliptocytes are commonly associated with hereditary elliptocytosis However they may also be seen in iron deficiency anemia sepsis malaria and other pathological states that decrease red blood cell turnover and or production 2 In the case of iron deficiency anemia microcytosis and hypochromia would also be expected 3 Contents 1 Causes 2 ReferencesCauses EditRare elliptocytes less than 1 on a peripheral blood smear are a normal finding citation needed These abnormal red blood cells are seen in higher numbers in the blood films of patients with blood disorders such as 4 Hereditary elliptocytosis and Southeast Asian ovalocytosis Thalassemia Iron deficiency Myelodysplastic syndrome and myelofibrosis Megaloblastic anemiaReferences Edit Ovalocytes Elliptocytes LabCE com Laboratory Continuing Education www labce com Retrieved 21 May 2018 Clinical hematology and oncology presentation diagnosis and treatment Bruce Furie Philadelphia Pa Churchill Livingstone 2003 pp 276 278 ISBN 0 443 06556 X OCLC 51582525 a href Template Cite book html title Template Cite book cite book a CS1 maint others link Robbins amp Cotran pathologic basis of disease Vinay Kumar Abul K Abbas Jon C Aster James A Perkins 10th ed Philadelphia PA 2021 ISBN 978 0 323 53113 9 OCLC 1191840836 a href Template Cite book html title Template Cite book cite book a CS1 maint location missing publisher link CS1 maint others link Hirschmann Douglas C Tkachuk 2007 Wintrobe s atlas of clinical hematology Philadelphia PA etc Lippincott Williams amp Wilkins ISBN 978 0781770231 This article about a disease of the blood or immune system is a stub You can help Wikipedia by expanding it vte This article related to pathology is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Elliptocyte amp oldid 1157905535, wikipedia, wiki, book, books, library,

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