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Deltaretrovirus

Deltaretrovirus is a genus of the Retroviridae family. It consists of exogenous horizontally transmitted viruses found in several groups of mammals. As of 2023, ICTV lists under this genus the Bovine leukemia virus and three species of primate T-lymphotropic virus.

Deltaretrovirus
Virus classification
(unranked): Virus
Realm: Riboviria
Kingdom: Pararnavirae
Phylum: Artverviricota
Class: Revtraviricetes
Order: Ortervirales
Family: Retroviridae
Subfamily: Orthoretrovirinae
Genus: Deltaretrovirus
Species

The genus of viruses is known for its propensity to target immune cells and oncogenity, evident in the names of the four named species.[1] Infection is usually asymptomatic, but inflammation and cancer can develop over time.[2]

Classification edit

Four species are recognized by the ICTV as of 2023:

Two additional PTLVs are known but not regonized: HTLV-4 (South Cameroon, 2005) and STLV-5 (Mac B43 strain, highly divergent PTLV-1).[3]

In addition, eight endogenous retroviruses identified as Deltaretrovirus are known as of 2019. Two of these were complete enough to show ORFs; the rest only showing long terminal repeats.[1]

Hosts edit

Known exogenous deltaretroviruses infect cattle and primates.[1]

The two complete endogenous ones were found in bats and dolphins; the others in Solenodon, mongoose, and fossa. These endogenous examples fill in the large gap in the host range.[1]

Clinical relevance edit

References edit

  1. ^ a b c d Hron, T; Elleder, D; Gifford, RJ (27 November 2019). "Deltaretroviruses have circulated since at least the Paleogene and infected a broad range of mammalian species". Retrovirology. 16 (1): 33. doi:10.1186/s12977-019-0495-9. PMC 6882180. PMID 31775783.
  2. ^ Farkašová, H; Hron, T; Pačes, J; Hulva, P; Benda, P; Gifford, RJ; Elleder, D (21 March 2017). "Discovery of an endogenous Deltaretrovirus in the genome of long-fingered bats (Chiroptera: Miniopteridae)". Proceedings of the National Academy of Sciences of the United States of America. 114 (12): 3145–3150. Bibcode:2017PNAS..114.3145F. doi:10.1073/pnas.1621224114. PMC 5373376. PMID 28280099.
  3. ^ Mahieux, R; Gessain, A (July 2011). "HTLV-3/STLV-3 and HTLV-4 viruses: discovery, epidemiology, serology and molecular aspects". Viruses. 3 (7): 1074–90. doi:10.3390/v3071074. PMC 3185789. PMID 21994771.

External links edit


deltaretrovirus, genus, retroviridae, family, consists, exogenous, horizontally, transmitted, viruses, found, several, groups, mammals, 2023, update, ictv, lists, under, this, genus, bovine, leukemia, virus, three, species, primate, lymphotropic, virus, virus,. Deltaretrovirus is a genus of the Retroviridae family It consists of exogenous horizontally transmitted viruses found in several groups of mammals As of 2023 update ICTV lists under this genus the Bovine leukemia virus and three species of primate T lymphotropic virus Deltaretrovirus Virus classification unranked Virus Realm Riboviria Kingdom Pararnavirae Phylum Artverviricota Class Revtraviricetes Order Ortervirales Family Retroviridae Subfamily Orthoretrovirinae Genus Deltaretrovirus Species Bovine leukemia virus Primate T lymphotropic virus 1 Primate T lymphotropic virus 2 Primate T lymphotropic virus 3 The genus of viruses is known for its propensity to target immune cells and oncogenity evident in the names of the four named species 1 Infection is usually asymptomatic but inflammation and cancer can develop over time 2 Contents 1 Classification 2 Hosts 3 Clinical relevance 4 References 5 External linksClassification editFour species are recognized by the ICTV as of 2023 Bovine leukemia virus Primate T lymphotropic virus 1 Primate T lymphotropic virus 2 Primate T lymphotropic virus 3 Two additional PTLVs are known but not regonized HTLV 4 South Cameroon 2005 and STLV 5 Mac B43 strain highly divergent PTLV 1 3 In addition eight endogenous retroviruses identified as Deltaretrovirus are known as of 2019 Two of these were complete enough to show ORFs the rest only showing long terminal repeats 1 Hosts editKnown exogenous deltaretroviruses infect cattle and primates 1 The two complete endogenous ones were found in bats and dolphins the others in Solenodon mongoose and fossa These endogenous examples fill in the large gap in the host range 1 Clinical relevance editMain article Human T lymphotropic virusReferences edit a b c d Hron T Elleder D Gifford RJ 27 November 2019 Deltaretroviruses have circulated since at least the Paleogene and infected a broad range of mammalian species Retrovirology 16 1 33 doi 10 1186 s12977 019 0495 9 PMC 6882180 PMID 31775783 Farkasova H Hron T Paces J Hulva P Benda P Gifford RJ Elleder D 21 March 2017 Discovery of an endogenous Deltaretrovirus in the genome of long fingered bats Chiroptera Miniopteridae Proceedings of the National Academy of Sciences of the United States of America 114 12 3145 3150 Bibcode 2017PNAS 114 3145F doi 10 1073 pnas 1621224114 PMC 5373376 PMID 28280099 Mahieux R Gessain A July 2011 HTLV 3 STLV 3 and HTLV 4 viruses discovery epidemiology serology and molecular aspects Viruses 3 7 1074 90 doi 10 3390 v3071074 PMC 3185789 PMID 21994771 External links editDeltaretrovirus at the U S National Library of Medicine Medical Subject Headings MeSH Viralzone Deltaretrovirus nbsp This virus related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Deltaretrovirus amp oldid 1137375360, wikipedia, wiki, book, books, library,

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