This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with 2-oxoglutarate as one donor, and incorporation of one atom o oxygen into each donor. The systematic name of this enzyme class is desacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4beta-hydroxylating). Other names in common use include desacetoxyvindoline 4-hydroxylase, desacetyoxyvindoline-17-hydroxylase, D17H, desacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase, and (4beta-hydroxylating). This enzyme participates in terpene indole and ipecac alkaloid biosynthesis.
ReferencesEdit
Foucher AL, McIntosh A, Douce G, Wastling J, Tait A, Turner CM (2006). "A proteomic analysis of arsenical drug resistance in Trypanosoma brucei". Proteomics. 6 (9): 2726–32. doi:10.1002/pmic.200500419. PMID 16526094.
De Carolis E, De Luca V (1993). "Purification, characterization, and kinetic analysis of a 2-oxoglutarate-dependent dioxygenase involved in vindoline biosynthesis from Catharanthus roseus". J. Biol. Chem. 268 (8): 5504–11. PMID 8449913.
Vazquez-Flota FA, De Luca V (1998). "Developmental and light regulation of desacetoxyvindoline 4-hydroxylase in catharanthus roseus (L.) G. Don. . Evidence Of a multilevel regulatory mechanism". Plant Physiol. 117 (4): 1351–61. doi:10.1104/pp.117.4.1351. PMC34899. PMID 9701591.
desacetoxyvindoline, hydroxylase, enzymology, desacetoxyvindoline, hydroxylase, enzyme, that, catalyzes, chemical, reactiondesacetoxyvindoline, hydroxylaseidentifiersec, 20cas, 132084, 4databasesintenzintenz, viewbrendabrenda, entryexpasynicezyme, viewkeggkegg. In enzymology a desacetoxyvindoline 4 hydroxylase EC 1 14 11 20 is an enzyme that catalyzes the chemical reactiondesacetoxyvindoline 4 hydroxylaseIdentifiersEC no 1 14 11 20CAS no 132084 83 4DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumGene OntologyAmiGO QuickGOSearchPMCarticlesPubMedarticlesNCBIproteins desacetoxyvindoline 2 oxoglutarate O2 displaystyle rightleftharpoons deacetylvindoline succinate CO2The 3 substrates of this enzyme are desacetoxyvindoline 2 oxoglutarate and O2 whereas its 3 products are deacetylvindoline succinate and CO2 This enzyme belongs to the family of oxidoreductases specifically those acting on paired donors with O2 as oxidant and incorporation or reduction of oxygen The oxygen incorporated need not be derived from O2 with 2 oxoglutarate as one donor and incorporation of one atom o oxygen into each donor The systematic name of this enzyme class is desacetoxyvindoline 2 oxoglutarate oxygen oxidoreductase 4beta hydroxylating Other names in common use include desacetoxyvindoline 4 hydroxylase desacetyoxyvindoline 17 hydroxylase D17H desacetoxyvindoline 2 oxoglutarate oxygen oxidoreductase and 4beta hydroxylating This enzyme participates in terpene indole and ipecac alkaloid biosynthesis References EditFoucher AL McIntosh A Douce G Wastling J Tait A Turner CM 2006 A proteomic analysis of arsenical drug resistance in Trypanosoma brucei Proteomics 6 9 2726 32 doi 10 1002 pmic 200500419 PMID 16526094 De Carolis E De Luca V 1993 Purification characterization and kinetic analysis of a 2 oxoglutarate dependent dioxygenase involved in vindoline biosynthesis from Catharanthus roseus J Biol Chem 268 8 5504 11 PMID 8449913 Vazquez Flota FA De Luca V 1998 Developmental and light regulation of desacetoxyvindoline 4 hydroxylase in catharanthus roseus L G Don Evidence Of a multilevel regulatory mechanism Plant Physiol 117 4 1351 61 doi 10 1104 pp 117 4 1351 PMC 34899 PMID 9701591 Portal nbsp Biology This EC 1 14 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Desacetoxyvindoline 4 hydroxylase amp oldid 1172344471, wikipedia, wiki, book, books, library,