dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose N,N-dimethyltransferase

DTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose N,N-dimethyltransferase (EC 2.1.1.236, RavNMT) is an enzyme with systematic name S-adenosyl-L-methionine:dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N,N-dimethyltransferase.^[1] This enzyme catalyses the following chemical reaction

DTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose N,N-dimethyltransferase
Identifiers
EC no.	2.1.1.236
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

2 S-adenosyl-L-methionine + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose ${\displaystyle \rightleftharpoons }$ 2 S-adenosyl-L-homocysteine + dTDP-3-dimethylamino-3,6-dideoxy-alpha-D-galactopyranose

The enzyme is involved in the synthesis of dTDP-D-ravidosamine.

References

1. Kharel MK, Lian H, Rohr J (March 2011). "Characterization of the TDP-D-ravidosamine biosynthetic pathway: one-pot enzymatic synthesis of TDP-D-ravidosamine from thymidine-5-phosphate and glucose-1-phosphate". Organic & Biomolecular Chemistry. 9 (6): 1799–808. doi:10.1039/c0ob00854k. PMC 4482361. PMID 21264378.

External links

• DTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose+N,N-dimethyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)