Cyclacel

Cyclacel Pharmaceuticals Inc. is a biotechnology firm based in Berkeley Heights, New Jersey and Dundee, Scotland, developing cancer treatments. Cyclacel was founded in 1996 by David Lane, PhD.

Cyclacel Pharmaceuticals, Inc.

Type	Public
Traded as	Nasdaq: CYCC
Industry	Biotechnology
Founded	1997
Headquarters	Berkeley Heights, New Jersey, U.S.
Key people	Spiro Rombotis, CEO David P. Lane, PhD, founder Paul McBarron, EVP, Finance & COO Mark Kirschbaum, MD, CMO
Products	Fadraciclib (formerly CYC065), CYC140
Net income	US$ 19.1 million (2021)
Number of employees	17 (2022)
Website	http://www.cyclacel.com

Company overview

Cyclacel Pharmaceuticals, Inc. is a clinical-stage, biopharmaceutical company developing innovative cancer medicines based on cell cycle, transcriptional regulation and mitosis biology. The transcriptional regulation program is evaluating fadraciclib, a CDK2/9 inhibitor, and the anti-mitotic program CYC140, a PLK1 inhibitor, in patients with both solid tumors and hematological malignancies. Cyclacel’s strategy is to build a diversified biopharmaceutical business based on a pipeline of novel drug candidates addressing oncology and hematology indications. For additional information, please visit www.cyclacel.com.

Sir David Lane, PhD, a recognized leader in the field of tumor suppressor biology, who discovered the p53 protein, founded the company in 1996. In 1999, Cyclacel Pharmaceuticals was joined by David Glover, PhD, a recognized leader in the mechanism of mitosis or cell division, who discovered, among other cell cycle targets, the mitotic kinases, Polo and Aurora, enzymes that act in the mitosis phase of the cell cycle.