This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 4,5alpha-dihydrocortisone:NADP+ Delta4-oxidoreductase. Other names in common use include cortisone Delta4-5alpha-reductase, microsomal steroid reductase (5alpha), Delta4-3-ketosteroid reductase (5alpha), Delta4-3-oxosteroid-5alpha-reductase, NADPH:Delta4-3-oxosteroid-5alpha-oxidoreductase, and Delta4-5alpha-reductase.
Referencesedit
McGuire JS, Hollis VW, Tomkins GM (1960). "Some characteristics of the microsomal steroid reductases (5alpha) of rat liver". J. Biol. Chem. 235: 3112–3117.
cortisone, alpha, reductase, enzymology, cortisone, alpha, reductase, enzyme, that, catalyzes, chemical, reactioncortisone, alpha, reductaseidentifiersec, 4cas, 9029, 8databasesintenzintenz, viewbrendabrenda, entryexpasynicezyme, viewkeggkegg, entrymetacycmeta. In enzymology a cortisone alpha reductase EC 1 3 1 4 is an enzyme that catalyzes the chemical reactioncortisone alpha reductaseIdentifiersEC no 1 3 1 4CAS no 9029 09 8DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumGene OntologyAmiGO QuickGOSearchPMCarticlesPubMedarticlesNCBIproteins 4 5alpha dihydrocortisone NADP displaystyle rightleftharpoons cortisone NADPH H Thus the two substrates of this enzyme are 4 5alpha dihydrocortisone and NADP whereas its 3 products are cortisone NADPH and H This enzyme belongs to the family of oxidoreductases specifically those acting on the CH CH group of donor with NAD or NADP as acceptor The systematic name of this enzyme class is 4 5alpha dihydrocortisone NADP Delta4 oxidoreductase Other names in common use include cortisone Delta4 5alpha reductase microsomal steroid reductase 5alpha Delta4 3 ketosteroid reductase 5alpha Delta4 3 oxosteroid 5alpha reductase NADPH Delta4 3 oxosteroid 5alpha oxidoreductase and Delta4 5alpha reductase References editMcGuire JS Hollis VW Tomkins GM 1960 Some characteristics of the microsomal steroid reductases 5alpha of rat liver J Biol Chem 235 3112 3117 Portal nbsp Biology This EC 1 3 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Cortisone alpha reductase amp oldid 1172385710, wikipedia, wiki, book, books, library,
