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Comorbidity–polypharmacy score

In medicine, the Comorbidity–polypharmacy score (CPS) is a measure of overall severity of comorbidities.[1] It is defined as the simple sum of the number of known comorbidities (concurrent conditions) and pre-admission medications taken by the patient (polypharmacy), as a surrogate for the “intensity” of the comorbidities.[2]

This score has been tested and validated extensively in the trauma population, demonstrating good correlation with mortality, morbidity, triage, and hospital readmissions.[3][4][5] Increasing levels of CPS were associated with significantly lower 90-day survival in the original study of the score in trauma population.[3]

Comparison with other comorbidity measures edit

The test is similar to the Charlson Comorbidity Index (CCI), but CPS also considers the number of medications taken, which is not a parameter in CCI. Additionally, CPS considers a wider range of comorbidities than CCI, and assigns the same weight to each.[2] A study comparing the two metrics found that CCI was a better predictor of mortality than CPS in older trauma patients.[6]

See also edit

References edit

  1. ^ Khanh, Linh Ngo; Helenowski, Irene B.; Hoel, Andrew W.; Ho, Karen J. (2020-11-01). "The Comorbidity-Polypharmacy Score is an Objective and Practical Predictor of Outcomes and Mortality after Vascular Surgery". Annals of Vascular Surgery. 69: 206–216. doi:10.1016/j.avsg.2020.05.055. ISSN 0890-5096. PMID 32502672. S2CID 219398575.
  2. ^ a b Stawicki, Stanislaw P.; Kalra, Sarathi; Jones, Christian; Justiniano, Carla F.; Papadimos, Thomas J.; Galwankar, Sagar C.; Pappada, Scott M.; Feeney, John J.; Evans, David C. (2015). "Comorbidity polypharmacy score and its clinical utility: A pragmatic practitioner's perspective". Journal of Emergencies, Trauma, and Shock. 8 (4): 224–231. doi:10.4103/0974-2700.161658. ISSN 0974-2700. PMC 4626940. PMID 26604529.
  3. ^ a b Evans, DC; Cook, CH; Christy, JM (August 2012). "Comorbidity–polypharmacy scoring facilitates outcome prediction in older trauma patients". J Am Geriatr Soc. 60 (8): 1465–70. doi:10.1111/j.1532-5415.2012.04075.x. PMID 22788674. S2CID 40542659.
  4. ^ Justiniano, CF; Coffey, RA; Evans, DC (Jan 2015). "Comorbidity–polypharmacy score predicts in-hospital complications and the need for discharge to extended care facility in older burn patients". J Burn Care Res. 36 (1): 193–96. doi:10.1097/bcr.0000000000000094. PMID 25559732. S2CID 3677354.
  5. ^ Justiniano, CF; Evans, DC; Cook, CH (May 2013). "Comorbidity–polypharmacy score: a novel adjunct in post-emergency department trauma triage". J Surg Res. 181 (1): 16–19. doi:10.1016/j.jss.2012.05.042. PMC 3717608. PMID 22683074.
  6. ^ Chua, Mui Teng; Pan, Darius Shaw Teng; Lee, Ming Zhou; Thajudeen, Mohammed Zuhary; Rahman, Mohamed Madeena Faizur; Sheth, Irfan Abdulrahman; Ong, Victor Yeok Kein; Tang, Jonathan Zhe Ying; Wee, Choon Peng Jeremy; Kuan, Win Sen (April 2023). "Comparing Comorbidity Polypharmacy Score and Charlson Comorbidity Index in predicting outcomes in older trauma patients". Injury. 54 (4): 1113–1118. doi:10.1016/j.injury.2023.02.031. ISSN 1879-0267. PMID 36822915. S2CID 257002026.


comorbidity, polypharmacy, score, medicine, measure, overall, severity, comorbidities, defined, simple, number, known, comorbidities, concurrent, conditions, admission, medications, taken, patient, polypharmacy, surrogate, intensity, comorbidities, this, score. In medicine the Comorbidity polypharmacy score CPS is a measure of overall severity of comorbidities 1 It is defined as the simple sum of the number of known comorbidities concurrent conditions and pre admission medications taken by the patient polypharmacy as a surrogate for the intensity of the comorbidities 2 This score has been tested and validated extensively in the trauma population demonstrating good correlation with mortality morbidity triage and hospital readmissions 3 4 5 Increasing levels of CPS were associated with significantly lower 90 day survival in the original study of the score in trauma population 3 Comparison with other comorbidity measures editThe test is similar to the Charlson Comorbidity Index CCI but CPS also considers the number of medications taken which is not a parameter in CCI Additionally CPS considers a wider range of comorbidities than CCI and assigns the same weight to each 2 A study comparing the two metrics found that CCI was a better predictor of mortality than CPS in older trauma patients 6 See also editComorbidity Charlson Comorbidity Index CCI Elixhauser Comorbidity IndexReferences edit Khanh Linh Ngo Helenowski Irene B Hoel Andrew W Ho Karen J 2020 11 01 The Comorbidity Polypharmacy Score is an Objective and Practical Predictor of Outcomes and Mortality after Vascular Surgery Annals of Vascular Surgery 69 206 216 doi 10 1016 j avsg 2020 05 055 ISSN 0890 5096 PMID 32502672 S2CID 219398575 a b Stawicki Stanislaw P Kalra Sarathi Jones Christian Justiniano Carla F Papadimos Thomas J Galwankar Sagar C Pappada Scott M Feeney John J Evans David C 2015 Comorbidity polypharmacy score and its clinical utility A pragmatic practitioner s perspective Journal of Emergencies Trauma and Shock 8 4 224 231 doi 10 4103 0974 2700 161658 ISSN 0974 2700 PMC 4626940 PMID 26604529 a b Evans DC Cook CH Christy JM August 2012 Comorbidity polypharmacy scoring facilitates outcome prediction in older trauma patients J Am Geriatr Soc 60 8 1465 70 doi 10 1111 j 1532 5415 2012 04075 x PMID 22788674 S2CID 40542659 Justiniano CF Coffey RA Evans DC Jan 2015 Comorbidity polypharmacy score predicts in hospital complications and the need for discharge to extended care facility in older burn patients J Burn Care Res 36 1 193 96 doi 10 1097 bcr 0000000000000094 PMID 25559732 S2CID 3677354 Justiniano CF Evans DC Cook CH May 2013 Comorbidity polypharmacy score a novel adjunct in post emergency department trauma triage J Surg Res 181 1 16 19 doi 10 1016 j jss 2012 05 042 PMC 3717608 PMID 22683074 Chua Mui Teng Pan Darius Shaw Teng Lee Ming Zhou Thajudeen Mohammed Zuhary Rahman Mohamed Madeena Faizur Sheth Irfan Abdulrahman Ong Victor Yeok Kein Tang Jonathan Zhe Ying Wee Choon Peng Jeremy Kuan Win Sen April 2023 Comparing Comorbidity Polypharmacy Score and Charlson Comorbidity Index in predicting outcomes in older trauma patients Injury 54 4 1113 1118 doi 10 1016 j injury 2023 02 031 ISSN 1879 0267 PMID 36822915 S2CID 257002026 nbsp This health related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Comorbidity polypharmacy score amp oldid 1188132451, wikipedia, wiki, book, books, library,

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