Wikipedia
Columbamine O-methyltransferase
In enzymology, a columbamine O-methyltransferase (EC 2.1.1.118) is an enzyme that catalyzes the chemical reaction
| columbamine O-methyltransferase | |
|---|---|
| Identifiers | |
| EC no. | 2.1.1.118 |
| CAS no. | 105843-76-3 |
| Databases | |
| IntEnz | IntEnz view |
| BRENDA | BRENDA entry |
| ExPASy | NiceZyme view |
| KEGG | KEGG entry |
| MetaCyc | metabolic pathway |
| PRIAM | profile |
| PDB structures | RCSB PDB PDBe PDBsum |
| Gene Ontology | AmiGO / QuickGO |
- S-adenosyl-L-methionine + columbamine S-adenosyl-L-homocysteine + palmatine
Thus, the two substrates of this enzyme are S-adenosyl methionine and columbamine, whereas its two products are S-adenosylhomocysteine and palmatine.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:columbamine O-methyltransferase. This enzyme participates in alkaloid biosynthesis i.
References edit
- Rueffer M, Amann M, Zenk MH (1986). "S-Adenosyl-L-methionine:columbamine O-methyltransferase, a compartmentalized enzyme in protoberberine biosynthesis". Plant Cell Reports. 3: 182–185.