Clue cells are epithelial cells of the vagina that get their distinctive stippled appearance by being covered with bacteria. The etymology behind the term "clue" cell derives from the original research article from Gardner and Dukes describing the characteristic cells. The name was chosen for its brevity in describing the sine qua non of bacterial vaginosis.[1]
Micrograph of a clue cell (center), covered in bacteria, as compared to an unremarkable squamous cell at bottom left, and a neutrophil at bottom center. Pap stainPhase contrast microscopy of clue cells in a vaginal swab
They are a medical sign of bacterial vaginosis, particularly that caused by Gardnerella vaginalis,[2] a group of Gram-variable bacteria. This bacterial infection is characterized by thin gray vaginal discharge, and an increase in vaginal pH from around 4.5 to over 5.5.
Bacteria obscuring the surfaces of vaginal epithelial cells, giving them a stippled appearance
Referencesedit
^Gardner, Herman; Dukes, Charles (May 1955). "Haemophilus vaginalis vaginitis: A newly defined specific infection previously classified "nonspecific" vaginitis". American Journal of Obstetrics and Gynecology. 69 (5): 962–976. doi:10.1016/0002-9378(55)90095-8. PMID 14361525.
^Scott TG, Smyth CJ, Keane CT (February 1987). "In vitro adhesiveness and biotype of Gardnerella vaginalis strains in relation to the occurrence of clue cells in vaginal discharges". Genitourinary Medicine. 63 (1): 47–53. doi:10.1136/sti.63.1.47. PMC1194007. PMID 3493202.
clue, cell, epithelial, cells, vagina, that, their, distinctive, stippled, appearance, being, covered, with, bacteria, etymology, behind, term, clue, cell, derives, from, original, research, article, from, gardner, dukes, describing, characteristic, cells, nam. Clue cells are epithelial cells of the vagina that get their distinctive stippled appearance by being covered with bacteria The etymology behind the term clue cell derives from the original research article from Gardner and Dukes describing the characteristic cells The name was chosen for its brevity in describing the sine qua non of bacterial vaginosis 1 Micrograph of a clue cell center covered in bacteria as compared to an unremarkable squamous cell at bottom left and a neutrophil at bottom center Pap stain Phase contrast microscopy of clue cells in a vaginal swab They are a medical sign of bacterial vaginosis particularly that caused by Gardnerella vaginalis 2 a group of Gram variable bacteria This bacterial infection is characterized by thin gray vaginal discharge and an increase in vaginal pH from around 4 5 to over 5 5 Bacteria obscuring the surfaces of vaginal epithelial cells giving them a stippled appearanceReferences edit Gardner Herman Dukes Charles May 1955 Haemophilus vaginalis vaginitis A newly defined specific infection previously classified nonspecific vaginitis American Journal of Obstetrics and Gynecology 69 5 962 976 doi 10 1016 0002 9378 55 90095 8 PMID 14361525 Scott TG Smyth CJ Keane CT February 1987 In vitro adhesiveness and biotype of Gardnerella vaginalis strains in relation to the occurrence of clue cells in vaginal discharges Genitourinary Medicine 63 1 47 53 doi 10 1136 sti 63 1 47 PMC 1194007 PMID 3493202 External links editOverview at WebMD Clue cell in Gram stain at Fun With Microbiology Clue cell in Papanicolaou stain at the http eknygos lsmuni lt nbsp This article related to pathology is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Clue cell amp oldid 1221594129, wikipedia, wiki, book, books, library,
