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Estradiol/levonorgestrel

Estradiol/levonorgestrel (E2/LNG), sold under brand name Climara Pro, is a combination of estradiol (E2) and levonorgestrel (LNG) which is used in menopausal hormone therapy.[1][2][3] It is a 22-cm2 transdermal patch containing 4.4 mg estradiol and 1.39 mg levonorgestrel and delivers 45 μg/day estradiol and 15 μg/day levonorgestrel.[1][4] E2/LNG was approved for medical use in the United States in 2003.[5]

Estradiol/levonorgestrel
Combination of
EstradiolEstrogen
LevonorgestrelProgestogen
Clinical data
Trade namesClimara Pro
Other namesE2/LNG
ATC code
Legal status
Legal status
Identifiers
CAS Number
  • 77728-33-7

See also edit

References edit

  1. ^ a b "Climara Pro Prescribing Information" (PDF). U.S. Food and Drug Administration.
  2. ^ Shulman LP (December 2004). "17Beta-estradiol/levonorgestrel transdermal system for the management of the symptomatic menopausal woman". Expert Opinion on Pharmacotherapy. 5 (12): 2559–66. doi:10.1517/14656566.5.12.2559. PMID 15571472. S2CID 24659973.
  3. ^ Dando TM, Perry CM (2004). "17 beta-estradiol/levonorgestrel transdermal system". Treatments in Endocrinology. 3 (5): 319–24. doi:10.2165/00024677-200403050-00005. PMID 15330679. S2CID 72554239.
  4. ^ Wiedersberg S, Guy RH (September 2014). "Transdermal drug delivery: 30+ years of war and still fighting!" (PDF). Journal of Controlled Release. 190: 150–6. doi:10.1016/j.jconrel.2014.05.022. PMID 24852092. S2CID 13842061.
  5. ^ Traynor K (February 2004). "New drug and biological product approvals, 2003". American Journal of Health-System Pharmacy. 61 (4): 338–340. doi:10.1093/ajhp/61.4.338. PMID 15011760.

estradiol, levonorgestrel, sold, under, brand, name, climara, combination, estradiol, levonorgestrel, which, used, menopausal, hormone, therapy, transdermal, patch, containing, estradiol, levonorgestrel, delivers, estradiol, levonorgestrel, approved, medical, . Estradiol levonorgestrel E2 LNG sold under brand name Climara Pro is a combination of estradiol E2 and levonorgestrel LNG which is used in menopausal hormone therapy 1 2 3 It is a 22 cm2 transdermal patch containing 4 4 mg estradiol and 1 39 mg levonorgestrel and delivers 45 mg day estradiol and 15 mg day levonorgestrel 1 4 E2 LNG was approved for medical use in the United States in 2003 5 Estradiol levonorgestrelCombination ofEstradiolEstrogenLevonorgestrelProgestogenClinical dataTrade namesClimara ProOther namesE2 LNGATC codeG03FA01 WHO Legal statusLegal statusUS onlyIdentifiersCAS Number77728 33 7See also editEstradiol norethisterone acetate Ethinylestradiol norelgestromin List of combined sex hormonal preparationsReferences edit a b Climara Pro Prescribing Information PDF U S Food and Drug Administration Shulman LP December 2004 17Beta estradiol levonorgestrel transdermal system for the management of the symptomatic menopausal woman Expert Opinion on Pharmacotherapy 5 12 2559 66 doi 10 1517 14656566 5 12 2559 PMID 15571472 S2CID 24659973 Dando TM Perry CM 2004 17 beta estradiol levonorgestrel transdermal system Treatments in Endocrinology 3 5 319 24 doi 10 2165 00024677 200403050 00005 PMID 15330679 S2CID 72554239 Wiedersberg S Guy RH September 2014 Transdermal drug delivery 30 years of war and still fighting PDF Journal of Controlled Release 190 150 6 doi 10 1016 j jconrel 2014 05 022 PMID 24852092 S2CID 13842061 Traynor K February 2004 New drug and biological product approvals 2003 American Journal of Health System Pharmacy 61 4 338 340 doi 10 1093 ajhp 61 4 338 PMID 15011760 nbsp This drug article relating to the genito urinary system is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Estradiol levonorgestrel amp oldid 1135715710, wikipedia, wiki, book, books, library,

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