Carmen Domene is a Spanish academic who is a professor of chemistry at the University of Bath. Her research makes use of computational simulations to understand biological systems and processes. She was awarded the 2020 International Society of Quantum Biology and Pharmacology Loew Award and the 2023 Royal Society of Chemistry Corday-Morgan Prize.
In 2012, Domene joined King's College London as a Reader in Chemistry.[citation needed] In 2017, she moved to the University of Bath. Her research makes use of molecular modelling to better understand biological materials and processes.[2] She uses molecular mechanics and basic laws of physics to understand atomic structure, and combinations of molecular and quantum mechanics to understand dynamic chemical processes.[2]
Domene makes use of supercomputers to investigate the molecular mechanisms of ion channels, including the transient receptor potential and potassium channels.[3] By better understanding how ion channels open and close, Domene looks to define how they are related to neurological conditions and chronic pain.[3] She used computational simulations to create a cell membrane, in which she could place specific proteins and recreate the environment inside and outside. Her simulations allow her to monitor ion movements and better understand which biomolecules are involved with ion gating or the modulation of channel activity.
Domene works on computational simulations for drug discovery.[3] To better understand how her proteins bind different chemical groups, Domene has simulated how her proteins respond to molecular environments.[3]
Awards and honoursedit
2020 International Society of Quantum Biology and Pharmacology Loew Award[4]
E Albertazzi; C Domene; P W. Fowler; T Heine; G Seifert; C Van Alsenoy; F Zerbetto (1999). "Pentagon adjacency as a determinant of fullerene stability". Physical Chemistry Chemical Physics. 1 (12): 2913–2918. doi:10.1039/A901600G. ISSN 1463-9076. Wikidata Q58279341.
Rasheduzzaman Chowdhury; Michael A McDonough; Jasmin Mecinovic; Christoph Loenarz; Emily Flashman; Kirsty S Hewitson; Carmen Domene; Christopher J. Schofield (1 July 2009). "Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases". Structure. 17 (7): 981–989. doi:10.1016/J.STR.2009.06.002. ISSN 0969-2126. PMID 19604478. Wikidata Q27656451.
Oliver Beckstein; Philip C. Biggin; Peter J Bond; Joanne N Bright; Carmen Domene; Alessandro Grottesi; John Holyoake; Mark S.P. Sansom (1 November 2003). "Ion channel gating: insights via molecular simulations". FEBS Letters. 555 (1): 85–90. doi:10.1016/S0014-5793(03)01151-7. ISSN 0014-5793. PMID 14630324. Wikidata Q35589991.
Referencesedit
^"Carmen Domene". the University of Bath's research portal. Retrieved 2023-06-25.
^ abSteinmark2017-06-28T08:18:00+01:00, Ida Emilie. "The rise of molecular modelling". RSC Education. Retrieved 2023-06-25.{{cite web}}: CS1 maint: numeric names: authors list (link)
^ abcd"PRACE Success Stories in Life Sciences" (PDF). PRACE-RI. 2020-04-17.
^admin. "AWARDS". The International Society of Quantum Biology and Pharmacology. Retrieved 2023-06-24.
^"Professor Carmen Domene - 2023 Corday-Morgan Prize winner". Royal Society of Chemistry. Retrieved 2023-06-24.
March 16, 2024
carmen, domene, this, biography, living, person, needs, additional, citations, verification, please, help, adding, reliable, sources, contentious, material, about, living, persons, that, unsourced, poorly, sourced, must, removed, immediately, from, article, ta. This biography of a living person needs additional citations for verification Please help by adding reliable sources Contentious material about living persons that is unsourced or poorly sourced must be removed immediately from the article and its talk page especially if potentially libelous Find sources Carmen Domene news newspapers books scholar JSTOR June 2023 Learn how and when to remove this template message Carmen Domene is a Spanish academic who is a professor of chemistry at the University of Bath Her research makes use of computational simulations to understand biological systems and processes She was awarded the 2020 International Society of Quantum Biology and Pharmacology Loew Award and the 2023 Royal Society of Chemistry Corday Morgan Prize Carmen DomeneAlma materUniversity of Exeter University of OxfordScientific careerInstitutionsKing s College London University of Oxford University of Bath University of PennsylvaniaThesisMany body effects in interionic interactions 2000 Contents 1 Early life and education 2 Research and career 3 Awards and honours 4 Selected publications 5 ReferencesEarly life and education editDomene is from Spain She was an undergraduate at the University of Seville 1 Domene was a graduate student at the University of Exeter where she worked on many body effects in interionic interactions with Patrick Fowler citation needed She was awarded a Royal Society University Research Fellowship and moved to the University of Oxford citation needed She then moved to the University of Pennsylvania She also worked with Michele Parrinello at ETH Zurich citation needed Research and career editIn 2012 Domene joined King s College London as a Reader in Chemistry citation needed In 2017 she moved to the University of Bath Her research makes use of molecular modelling to better understand biological materials and processes 2 She uses molecular mechanics and basic laws of physics to understand atomic structure and combinations of molecular and quantum mechanics to understand dynamic chemical processes 2 Domene makes use of supercomputers to investigate the molecular mechanisms of ion channels including the transient receptor potential and potassium channels 3 By better understanding how ion channels open and close Domene looks to define how they are related to neurological conditions and chronic pain 3 She used computational simulations to create a cell membrane in which she could place specific proteins and recreate the environment inside and outside Her simulations allow her to monitor ion movements and better understand which biomolecules are involved with ion gating or the modulation of channel activity Domene works on computational simulations for drug discovery 3 To better understand how her proteins bind different chemical groups Domene has simulated how her proteins respond to molecular environments 3 Awards and honours edit2020 International Society of Quantum Biology and Pharmacology Loew Award 4 2023 Corday Morgan Prize 5 Selected publications editE Albertazzi C Domene P W Fowler T Heine G Seifert C Van Alsenoy F Zerbetto 1999 Pentagon adjacency as a determinant of fullerene stability Physical Chemistry Chemical Physics 1 12 2913 2918 doi 10 1039 A901600G ISSN 1463 9076 Wikidata Q58279341 Rasheduzzaman Chowdhury Michael A McDonough Jasmin Mecinovic Christoph Loenarz Emily Flashman Kirsty S Hewitson Carmen Domene Christopher J Schofield 1 July 2009 Structural basis for binding of hypoxia inducible factor to the oxygen sensing prolyl hydroxylases Structure 17 7 981 989 doi 10 1016 J STR 2009 06 002 ISSN 0969 2126 PMID 19604478 Wikidata Q27656451 Oliver Beckstein Philip C Biggin Peter J Bond Joanne N Bright Carmen Domene Alessandro Grottesi John Holyoake Mark S P Sansom 1 November 2003 Ion channel gating insights via molecular simulations FEBS Letters 555 1 85 90 doi 10 1016 S0014 5793 03 01151 7 ISSN 0014 5793 PMID 14630324 Wikidata Q35589991 References edit Carmen Domene the University of Bath s research portal Retrieved 2023 06 25 a b Steinmark2017 06 28T08 18 00 01 00 Ida Emilie The rise of molecular modelling RSC Education Retrieved 2023 06 25 a href Template Cite web html title Template Cite web cite web a CS1 maint numeric names authors list link a b c d PRACE Success Stories in Life Sciences PDF PRACE RI 2020 04 17 admin AWARDS The International Society of Quantum Biology and Pharmacology Retrieved 2023 06 24 Professor Carmen Domene 2023 Corday Morgan Prize winner Royal Society of Chemistry Retrieved 2023 06 24 Retrieved from https en wikipedia org w index php title Carmen Domene amp oldid 1179803237, wikipedia, wiki, book, books, library,
