CFU-Meg is a colony forming unit. Haematopoiesis in the bone marrow starts off from a haematopoietic stem cell (HSC) and this can differentiate into the myeloid and lymphoid cell lineages. In order to eventually produce a megakaryocyte, the haematopoietic stem cell must generate myeloid cells, so it becomes a common myeloid progenitor, CFU-GEMM. This in turn develops into CFU-Meg, which is the colony forming unit that leads to the production of megakaryocytes.[1][2][3]
^Kimura H, Ohkoshi T, Matsuda S, Uchida T, Kariyone S (1988). "Megakaryocytopoiesis in polycythemia vera: characterization by megakaryocytic progenitors (CFU-Meg) in vitro and quantitation of marrow megakaryocytes". Acta Haematol. 79 (1): 1–6. doi:10.1159/000205681. PMID 3124455.
^Kimura H, Ishibashi T, Sato T, Matsuda S, Uchida T, Kariyone S (January 1987). "Megakaryocytic colony formation (CFU-Meg) in essential thrombocythemia: quantitative and qualitative abnormalities of bone marrow CFU-Meg". Am. J. Hematol. 24 (1): 23–30. doi:10.1002/ajh.2830240104. PMID 3799592. S2CID 20893511.
^Gallicchio VS, Hughes NK, Hulette BC, Noblitt L (December 1991). "Effect of interleukin-1, GM-CSF, erythropoietin, and lithium on the toxicity associated with 3'-azido-3'-deoxythymidine (AZT) in vitro on hematopoietic progenitors (CFU-GM, CFU-MEG, and BFU-E) using murine retrovirus-infected hematopoietic cells". J. Leukoc. Biol. 50 (6): 580–6. doi:10.1002/jlb.50.6.580. PMID 1940611. S2CID 9700067.[permanent dead link]
^Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. (2005). Robbins and Cotran pathologic basis of disease. St. Louis, Mo: Elsevier Saunders. p. 621. ISBN0-7216-0187-1.
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Megakaryocyte+Progenitor+Cells at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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colony, forming, unit, haematopoiesis, bone, marrow, starts, from, haematopoietic, stem, cell, this, differentiate, into, myeloid, lymphoid, cell, lineages, order, eventually, produce, megakaryocyte, haematopoietic, stem, cell, must, generate, myeloid, cells, . CFU Meg is a colony forming unit Haematopoiesis in the bone marrow starts off from a haematopoietic stem cell HSC and this can differentiate into the myeloid and lymphoid cell lineages In order to eventually produce a megakaryocyte the haematopoietic stem cell must generate myeloid cells so it becomes a common myeloid progenitor CFU GEMM This in turn develops into CFU Meg which is the colony forming unit that leads to the production of megakaryocytes 1 2 3 CFU MegDetailsGives rise toMegakaryocytes and those to plateletsLocationBone marrowFunctionColony forming unitIdentifiersTHH2 00 04 3 02013Anatomical terms of microanatomy edit on Wikidata Some sources prefer the term CFU Mega 4 See also editThrombopoietinReferences edit Kimura H Ohkoshi T Matsuda S Uchida T Kariyone S 1988 Megakaryocytopoiesis in polycythemia vera characterization by megakaryocytic progenitors CFU Meg in vitro and quantitation of marrow megakaryocytes Acta Haematol 79 1 1 6 doi 10 1159 000205681 PMID 3124455 Kimura H Ishibashi T Sato T Matsuda S Uchida T Kariyone S January 1987 Megakaryocytic colony formation CFU Meg in essential thrombocythemia quantitative and qualitative abnormalities of bone marrow CFU Meg Am J Hematol 24 1 23 30 doi 10 1002 ajh 2830240104 PMID 3799592 S2CID 20893511 Gallicchio VS Hughes NK Hulette BC Noblitt L December 1991 Effect of interleukin 1 GM CSF erythropoietin and lithium on the toxicity associated with 3 azido 3 deoxythymidine AZT in vitro on hematopoietic progenitors CFU GM CFU MEG and BFU E using murine retrovirus infected hematopoietic cells J Leukoc Biol 50 6 580 6 doi 10 1002 jlb 50 6 580 PMID 1940611 S2CID 9700067 permanent dead link Cotran Ramzi S Kumar Vinay Fausto Nelson Nelso Fausto Robbins Stanley L Abbas Abul K 2005 Robbins and Cotran pathologic basis of disease St Louis Mo Elsevier Saunders p 621 ISBN 0 7216 0187 1 External links editMegakaryocyte Progenitor Cells at the U S National Library of Medicine Medical Subject Headings MeSH nbsp This cell biology article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title CFU Meg amp oldid 1089620054, wikipedia, wiki, book, books, library,
