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CDP-diacylglycerol—inositol 3-phosphatidyltransferase

In enzymology, a CDP-diacylglycerol—inositol 3-phosphatidyltransferase (EC 2.7.8.11) is an enzyme that catalyzes the chemical reaction

CDP-diacylglycerol-inositol 3-phosphatidyltransferase
CDP-diacylglycerol--inositol 3-phosphatidyltransferase homodimer, Mycobacterium tuberculosis
Identifiers
EC no.2.7.8.11
CAS no.9027-01-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
CDP-diacylglycerol + myo-inositol CMP + phosphatidyl-1D-myo-inositol

Thus, the two substrates of this enzyme are CDP-diacylglycerol and myo-inositol, whereas its two products are CMP and phosphatidyl-1D-myo-inositol.

This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase. Other names in common use include CDP-diglyceride-inositol phosphatidyltransferase, phosphatidylinositol synthase, CDP-diacylglycerol-inositol phosphatidyltransferase, CDP-diglyceride:inositol transferase, cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:myo-inositol, 3-phosphatidyltransferase, CDP-DG:inositol transferase, cytidine diphosphodiglyceride-inositol phosphatidyltransferase, CDP-diacylglycerol:myo-inositol-3-phosphatidyltransferase, CDP-diglyceride-inositol transferase, cytidine diphosphoglyceride-inositol phosphatidyltransferase, and cytidine diphosphoglyceride-inositol transferase. This enzyme participates in glycerophospholipid metabolism and phosphatidylinositol signaling system.

References edit

  • Bleasdale JE, Wallis P, MacDonald PC, Johnston JM (1979). "Characterization of the forward and reverse reactions catalyzed by CDP-diacylglycerol:inositol transferase in rabbit lung tissue". Biochim. Biophys. Acta. 575 (1): 135–47. doi:10.1016/0005-2760(79)90139-5. PMID 41587.
  • Prottey C, Hawthorne JN (1967). "The biosynthesis of phosphatidic acid and phosphatidylinositol in mammalian pancreas". Biochem. J. 105 (1): 379–92. PMC 1198310. PMID 4293959.
  • Salway JG, Harwood JL, Kai M, White GL, Haworne JN (1968). "Enzymes of phosphoinositide metabolism during rat brain development". J. Neurochem. 15 (3): 221–6. doi:10.1111/j.1471-4159.1968.tb06200.x. PMID 4295616.
  • Takenawa T, Egawa K (1977). "CDP-diglyceride:inositol transferase from rat liver. Purification and properties". J. Biol. Chem. 252 (15): 5419–23. PMID 18462.


diacylglycerol, inositol, phosphatidyltransferase, this, article, includes, list, references, related, reading, external, links, sources, remain, unclear, because, lacks, inline, citations, please, help, improve, this, article, introducing, more, precise, cita. This article includes a list of references related reading or external links but its sources remain unclear because it lacks inline citations Please help improve this article by introducing more precise citations September 2018 Learn how and when to remove this template message In enzymology a CDP diacylglycerol inositol 3 phosphatidyltransferase EC 2 7 8 11 is an enzyme that catalyzes the chemical reactionCDP diacylglycerol inositol 3 phosphatidyltransferaseCDP diacylglycerol inositol 3 phosphatidyltransferase homodimer Mycobacterium tuberculosisIdentifiersEC no 2 7 8 11CAS no 9027 01 4DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumGene OntologyAmiGO QuickGOSearchPMCarticlesPubMedarticlesNCBIproteins CDP diacylglycerol myo inositol displaystyle rightleftharpoons CMP phosphatidyl 1D myo inositolThus the two substrates of this enzyme are CDP diacylglycerol and myo inositol whereas its two products are CMP and phosphatidyl 1D myo inositol This enzyme belongs to the family of transferases specifically those transferring non standard substituted phosphate groups The systematic name of this enzyme class is CDP diacylglycerol myo inositol 3 phosphatidyltransferase Other names in common use include CDP diglyceride inositol phosphatidyltransferase phosphatidylinositol synthase CDP diacylglycerol inositol phosphatidyltransferase CDP diglyceride inositol transferase cytidine 5 diphospho 1 2 diacyl sn glycerol myo inositol 3 phosphatidyltransferase CDP DG inositol transferase cytidine diphosphodiglyceride inositol phosphatidyltransferase CDP diacylglycerol myo inositol 3 phosphatidyltransferase CDP diglyceride inositol transferase cytidine diphosphoglyceride inositol phosphatidyltransferase and cytidine diphosphoglyceride inositol transferase This enzyme participates in glycerophospholipid metabolism and phosphatidylinositol signaling system References editBleasdale JE Wallis P MacDonald PC Johnston JM 1979 Characterization of the forward and reverse reactions catalyzed by CDP diacylglycerol inositol transferase in rabbit lung tissue Biochim Biophys Acta 575 1 135 47 doi 10 1016 0005 2760 79 90139 5 PMID 41587 Prottey C Hawthorne JN 1967 The biosynthesis of phosphatidic acid and phosphatidylinositol in mammalian pancreas Biochem J 105 1 379 92 PMC 1198310 PMID 4293959 Salway JG Harwood JL Kai M White GL Haworne JN 1968 Enzymes of phosphoinositide metabolism during rat brain development J Neurochem 15 3 221 6 doi 10 1111 j 1471 4159 1968 tb06200 x PMID 4295616 Takenawa T Egawa K 1977 CDP diglyceride inositol transferase from rat liver Purification and properties J Biol Chem 252 15 5419 23 PMID 18462 Portal nbsp Biology This EC 2 7 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title CDP diacylglycerol inositol 3 phosphatidyltransferase amp oldid 1172342023, wikipedia, wiki, book, books, library,

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