Bitot's spots are the buildup of keratin located superficially in the conjunctiva of human's eyes. They can be oval, triangular or irregular in shape. The spots are a sign of vitamin A deficiency and associated with drying of the cornea. In 1863, the French physician Pierre Bitot (1822–1888) first described these spots.[1] The spots may abate under replacement therapy.[2] In ancient Egypt, this was treated with animal liver, which is where vitamin A is stored.[3]
A major cause of Bitot's spots is vitamin A deficiency (VAD).[4] Rarely, pellagra due to deficiency of vitamin B3 (niacin) may also cause Bitot's spots.[5] They can also be caused by Colestyramine , which is a bile acid sequestrant which can reduce the absorption of fat soluble vitamins (Vitamins A, D, E, K)
Treatmentedit
VAD is commonly treated with oral vitamin A supplements.[6] Improvement of Bitot's spots is seen with high-dose vitamin A therapy.[7] Bitot's spots non-responsive to vitamin A therapy may be removed surgically.[8]
^Gilbert, Clare (2013). "The eye signs of vitamin A deficiency". Community Eye Health. 26 (84): 66–67. ISSN 0953-6833. PMC3936686. PMID 24782581.
^Levine, Robert A.; Rabb, Maurice F. (1 November 1971). "Bitot's Spot Overlying a Pinguecula". Archives of Ophthalmology. 86 (5): 525–528. doi:10.1001/archopht.1971.01000010527007. PMID 5315641.
^"Vitamin A Deficiency Treatment & Management: Medical Care, Consultations, Diet". 9 November 2019.
^"Management of Bitot's Spots". American Academy of Ophthalmology. 1 December 2016.
^Themes, U. F. O. (11 September 2016). "Bitot's Spots". Ento Key.
External linksedit
This medical sign article is a stub. You can help Wikipedia by expanding it.
bitot, spots, buildup, keratin, located, superficially, conjunctiva, human, eyes, they, oval, triangular, irregular, shape, spots, sign, vitamin, deficiency, associated, with, drying, cornea, 1863, french, physician, pierre, bitot, 1822, 1888, first, described. Bitot s spots are the buildup of keratin located superficially in the conjunctiva of human s eyes They can be oval triangular or irregular in shape The spots are a sign of vitamin A deficiency and associated with drying of the cornea In 1863 the French physician Pierre Bitot 1822 1888 first described these spots 1 The spots may abate under replacement therapy 2 In ancient Egypt this was treated with animal liver which is where vitamin A is stored 3 Bitot s spotsOther namesICD10 E50 1Typical location of Bitot s spotsSpecialtyOphthalmology Contents 1 Causes 2 Treatment 3 References 4 External linksCauses editA major cause of Bitot s spots is vitamin A deficiency VAD 4 Rarely pellagra due to deficiency of vitamin B3 niacin may also cause Bitot s spots 5 They can also be caused by Colestyramine which is a bile acid sequestrant which can reduce the absorption of fat soluble vitamins Vitamins A D E K Treatment editVAD is commonly treated with oral vitamin A supplements 6 Improvement of Bitot s spots is seen with high dose vitamin A therapy 7 Bitot s spots non responsive to vitamin A therapy may be removed surgically 8 References edit Shukla M Behari K Jul 1979 Congenital Bitot spots Indian Journal of Ophthalmology 27 2 63 4 PMID 541036 Ram Jagat Jinagal Jitender 2018 Bitot s Spots New England Journal of Medicine 379 9 869 doi 10 1056 NEJMicm1715354 PMID 30157394 S2CID 52126826 Numitor Gerd February 2012 Bitot s Spots Flu Press ISBN 978 620 0 57824 2 Gilbert Clare 2013 The eye signs of vitamin A deficiency Community Eye Health 26 84 66 67 ISSN 0953 6833 PMC 3936686 PMID 24782581 Levine Robert A Rabb Maurice F 1 November 1971 Bitot s Spot Overlying a Pinguecula Archives of Ophthalmology 86 5 525 528 doi 10 1001 archopht 1971 01000010527007 PMID 5315641 Vitamin A Deficiency Treatment amp Management Medical Care Consultations Diet 9 November 2019 Management of Bitot s Spots American Academy of Ophthalmology 1 December 2016 Themes U F O 11 September 2016 Bitot s Spots Ento Key External links edit nbsp This medical sign article is a stub You can help Wikipedia by expanding it vte nbsp This article about the eye is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Bitot 27s spots amp oldid 1203002398, wikipedia, wiki, book, books, library,
