Wikipedia
Bilirubin-glucuronoside glucuronosyltransferase
In enzymology, a bilirubin-glucuronoside glucuronosyltransferase (EC 2.4.1.95) is an enzyme that catalyzes the chemical reaction
| bilirubin-glucuronoside glucuronosyltransferase | |
|---|---|
| Identifiers | |
| EC no. | 2.4.1.95 |
| CAS no. | 71822-22-5 |
| Databases | |
| IntEnz | IntEnz view |
| BRENDA | BRENDA entry |
| ExPASy | NiceZyme view |
| KEGG | KEGG entry |
| MetaCyc | metabolic pathway |
| PRIAM | profile |
| PDB structures | RCSB PDB PDBe PDBsum |
| Gene Ontology | AmiGO / QuickGO |
- 2 bilirubin-glucuronoside bilirubin + bilirubin-bisglucuronoside
Hence, this enzyme has one substrate, bilirubin-glucuronoside, and two products, bilirubin and bilirubin-bisglucuronoside.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is bilirubin-glucuronoside:bilirubin-glucuronoside D-glucuronosyltransferase. Other names in common use include bilirubin monoglucuronide transglucuronidase, and bilirubin glucuronoside glucuronosyltransferase.
References edit
- Jansen PL, Chowdhury JR, Fischberg EB, Arias IM (1977). "Enzymatic conversion of bilirubin monoglucuronide to diglucuronide by rat liver plasma membranes". J. Biol. Chem. 252 (8): 2710–6. doi:10.1016/S0021-9258(17)40517-5. PMID 15996.