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Bil Clemons

April 09, 2024

William "Bil" Clemons, Jr. is an American structural biologist and Professor of Biochemistry at Caltech.[1] He is best known for his work solving the atomic structure of the ribosome with dissertation advisor, Nobel Prize winner in Chemistry, Venki Ramakrishnan.[2] He is also known for his work on the structure and function of proteins involved in membrane translocation and docking of proteins, including the membrane protein translocation channel SecY,[3] chaperones involved in the targeting of tail-anchored membrane proteins in the Get pathway,[4] and signal recognition proteins of the Twin-arginine translocation pathway.[5] He was elected a member of the National Academy of Sciences in 2022.[6]

William M. Clemons, Jr.
NationalityAmerican
Alma mater
Known forAtomic structures of the ribosome, translocon
Scientific career
Fields
Institutions
ThesisThe structure of the small ribosomal subunit (2000)
Doctoral advisorVenki Ramakrishnan
Other academic advisors
Websitehttp://clemonslab.caltech.edu

Education edit

Clemons received a B.S. in biochemistry from Virginia Polytechnic Institute and State University in 1995. In 2000, he received his Ph.D. in biochemistry from the University of Utah while working jointly with the Laboratory of Molecular Biology, in Cambridge, England under the advisement of Venki Ramakrishnan. He then spent four years, from 2001 to 2005, as a postdoctoral fellow under Professor Tom Rapoport in the Department of Cell Biology at Harvard Medical School.

Career edit

In January 2006, Clemons began as an assistant professor in the Chemistry and Chemical Engineering Division at the California Institute of Technology.[7] In 2013, Clemons became professor of Biochemistry. He has also held a Visiting Professor appointment from 2018-2019 at the Institute of Organic Chemistry & Biochemistry, Prague, Czech Republic.

Diversity and Inclusion edit

As a member of the President's Diversity Council at Caltech, Clemons mentors and advocates for diversity and enrollment of minority students in STEM education.[8] He has spoken on the intersection of science and diversity as an invited speaker.[8]

Clemons serves as a Science Program Officer for the Chan Zuckerberg Initiative.[9]

Honors and awards edit

  • 2018 Virginia Tech Biochemistry - Distinguished Alumni[10][11]
  • 2017 Dr. Fred Shair Award for Programming Diversity[12][13]
  • 2011-2016 NIH Pioneer Award[14]
  • 2005-2010 Burroughs Wellcome Career Award in the Biomedical Sciences[7]

References edit

  1. ^ Bil Clemons publications from Europe PubMed Central
  2. ^ Ramakrishnan, Venki (September 20, 2018). "Getting started in Utah". Gene Machine: The Race to Decipher the Secrets of the Ribosome. Oneworld Publications. ISBN 9781786074379.
  3. ^ Cannon, Kurt S.; Or, Eran; Clemons, William M.; Shibata, Yoko; Rapoport, Tom A. (2005). "Disulfide bridge formation between SecY and a translocating polypeptide localizes the translocation pore to the center of SecY". Journal of Cell Biology. 169 (2): 219–225. doi:10.1083/jcb.200412019. ISSN 1540-8140. PMC 2171872. PMID 15851514.
  4. ^ Suloway, C. J. M.; Chartron, J. W.; Zaslaver, M.; Clemons, W. M. (2009). "Model for eukaryotic tail-anchored protein binding based on the structure of Get3". Proceedings of the National Academy of Sciences. 106 (35): 14849–14854. Bibcode:2009PNAS..10614849S. doi:10.1073/pnas.0907522106. ISSN 0027-8424. PMC 2736419. PMID 19706470.
  5. ^ Ramasamy, Sureshkumar; Abrol, Ravinder; Suloway, Christian; Clemons, William (2013). "The Glove-like Structure of the Conserved Membrane Protein TatC Provides Insight into Signal Sequence Recognition in Twin-Arginine Translocation". Structure. 21 (5): 777–788. doi:10.1016/j.str.2013.03.004. ISSN 0969-2126. PMC 3653977. PMID 23583035.
  6. ^ "2022 NAS Election".
  7. ^ a b "Awardee Profile - Bil Clemons | Burroughs Wellcome Fund". www.bwfund.org. Retrieved 2020-08-16.
  8. ^ a b "Distinguished biochemist speaks on diversity in science and academia". College of Science | Oregon State University. 2019-10-24. Retrieved 2020-08-17.
  9. ^ "Science Team at Chan Zuckerberg Initiative". chanzuckerberg.com. Chan Zuckerberg Initiative. Retrieved 23 Jan 2023.
  10. ^ "Featured Alumni". biochem.vt.edu. from the original on 2020-10-20. Retrieved 2021-06-17.
  11. ^ "2017-18 Alumni Award Recipients". www.cals.vt.edu. from the original on 2021-06-24. Retrieved 2021-06-17.
  12. ^ "Past Recipients | Center for Inclusion & Diversity". diversity.caltech.edu. Retrieved 2020-08-16.
  13. ^ "ENGEL HALL NEWS BIOCHEMISTRY" (PDF). 2018.
  14. ^ "Project Information - NIH RePORTER - NIH Research Portfolio Online Reporting Tools Expenditures and Results". projectreporter.nih.gov. Retrieved 2020-08-16.

External links edit

April 09, 2024
clemons, this, article, includes, list, general, references, lacks, sufficient, corresponding, inline, citations, please, help, improve, this, article, introducing, more, precise, citations, july, 2020, learn, when, remove, this, template, message, william, cl. This article includes a list of general references but it lacks sufficient corresponding inline citations Please help to improve this article by introducing more precise citations July 2020 Learn how and when to remove this template message William Bil Clemons Jr is an American structural biologist and Professor of Biochemistry at Caltech 1 He is best known for his work solving the atomic structure of the ribosome with dissertation advisor Nobel Prize winner in Chemistry Venki Ramakrishnan 2 He is also known for his work on the structure and function of proteins involved in membrane translocation and docking of proteins including the membrane protein translocation channel SecY 3 chaperones involved in the targeting of tail anchored membrane proteins in the Get pathway 4 and signal recognition proteins of the Twin arginine translocation pathway 5 He was elected a member of the National Academy of Sciences in 2022 6 William M Clemons Jr NationalityAmericanAlma materVirginia Tech BS University of Utah PhD Known forAtomic structures of the ribosome transloconScientific careerFieldsStructural biology Membrane proteinsInstitutionsCalifornia Institute of Technology IOCB Prague Harvard Medical School Laboratory of Molecular BiologyThesisThe structure of the small ribosomal subunit 2000 Doctoral advisorVenki RamakrishnanOther academic advisorsTom Rapoport Stephen C HarrisonWebsitehttp clemonslab caltech edu Contents 1 Education 2 Career 2 1 Diversity and Inclusion 3 Honors and awards 4 References 5 External linksEducation editClemons received a B S in biochemistry from Virginia Polytechnic Institute and State University in 1995 In 2000 he received his Ph D in biochemistry from the University of Utah while working jointly with the Laboratory of Molecular Biology in Cambridge England under the advisement of Venki Ramakrishnan He then spent four years from 2001 to 2005 as a postdoctoral fellow under Professor Tom Rapoport in the Department of Cell Biology at Harvard Medical School Career editIn January 2006 Clemons began as an assistant professor in the Chemistry and Chemical Engineering Division at the California Institute of Technology 7 In 2013 Clemons became professor of Biochemistry He has also held a Visiting Professor appointment from 2018 2019 at the Institute of Organic Chemistry amp Biochemistry Prague Czech Republic Diversity and Inclusion edit As a member of the President s Diversity Council at Caltech Clemons mentors and advocates for diversity and enrollment of minority students in STEM education 8 He has spoken on the intersection of science and diversity as an invited speaker 8 Clemons serves as a Science Program Officer for the Chan Zuckerberg Initiative 9 Honors and awards edit2018 Virginia Tech Biochemistry Distinguished Alumni 10 11 2017 Dr Fred Shair Award for Programming Diversity 12 13 2011 2016 NIH Pioneer Award 14 2005 2010 Burroughs Wellcome Career Award in the Biomedical Sciences 7 References edit Bil Clemons publications from Europe PubMed Central Ramakrishnan Venki September 20 2018 Getting started in Utah Gene Machine The Race to Decipher the Secrets of the Ribosome Oneworld Publications ISBN 9781786074379 Cannon Kurt S Or Eran Clemons William M Shibata Yoko Rapoport Tom A 2005 Disulfide bridge formation between SecY and a translocating polypeptide localizes the translocation pore to the center of SecY Journal of Cell Biology 169 2 219 225 doi 10 1083 jcb 200412019 ISSN 1540 8140 PMC 2171872 PMID 15851514 Suloway C J M Chartron J W Zaslaver M Clemons W M 2009 Model for eukaryotic tail anchored protein binding based on the structure of Get3 Proceedings of the National Academy of Sciences 106 35 14849 14854 Bibcode 2009PNAS 10614849S doi 10 1073 pnas 0907522106 ISSN 0027 8424 PMC 2736419 PMID 19706470 Ramasamy Sureshkumar Abrol Ravinder Suloway Christian Clemons William 2013 The Glove like Structure of the Conserved Membrane Protein TatC Provides Insight into Signal Sequence Recognition in Twin Arginine Translocation Structure 21 5 777 788 doi 10 1016 j str 2013 03 004 ISSN 0969 2126 PMC 3653977 PMID 23583035 2022 NAS Election a b Awardee Profile Bil Clemons Burroughs Wellcome Fund www bwfund org Retrieved 2020 08 16 a b Distinguished biochemist speaks on diversity in science and academia College of Science Oregon State University 2019 10 24 Retrieved 2020 08 17 Science Team at Chan Zuckerberg Initiative chanzuckerberg com Chan Zuckerberg Initiative Retrieved 23 Jan 2023 Featured Alumni biochem vt edu Archived from the original on 2020 10 20 Retrieved 2021 06 17 2017 18 Alumni Award Recipients www cals vt edu Archived from the original on 2021 06 24 Retrieved 2021 06 17 Past Recipients Center for Inclusion amp Diversity diversity caltech edu Retrieved 2020 08 16 ENGEL HALL NEWS BIOCHEMISTRY PDF 2018 Project Information NIH RePORTER NIH Research Portfolio Online Reporting Tools Expenditures and Results projectreporter nih gov Retrieved 2020 08 16 External links edithttps www bwfund org newsroom awardee profiles awardee profile bil clemons https sbgrid org software tale predicting success https www biochem vt edu people Featured Alumni html https science oregonstate edu IMPACT 2018 02 distinguished biochemist speak diversity science higher education Bil Clemons publications indexed by Google Scholar Retrieved from https en wikipedia org w index php title Bil Clemons amp oldid 1198337747, wikipedia, wiki, book, books, library,

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