(Z)-hexadec-11-enoyl-[acyl-carrier-protein] + malonyl-[acyl-carrier-protein] (Z)-3-oxooctadec-13-enoyl-[acyl-carrier-protein] + CO2 + [acyl-carrier-protein]
Thus, the two substrates of this enzyme are (Z)-hexadec-11-enoyl-[acyl-carrier-protein] and malonyl-[acyl-carrier-protein], whereas its 3 products are (Z)-3-oxooctadec-13-enoyl-[acyl-carrier-protein], CO2, and acyl-carrier-protein.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is (Z)-hexadec-11-enoyl-[acyl-carrier-protein]:malonyl-[acyl-carrier-pr otein] C-acyltransferase (decarboxylating). Other names in common use include KASII, KAS II, FabF, 3-oxoacyl-acyl carrier protein synthase I, and beta-ketoacyl-ACP synthase II. This enzyme participates in fatty acid biosynthesis.
Referencesedit
D'Agnolo G, Rosenfeld IS, Vagelos PR (1975). "Multiple forms of beta-ketoacyl-acyl carrier protein synthetase in Escherichia coli". J. Biol. Chem. 250 (14): 5289–94. PMID 237914.
Garwin JL, Klages AL, Cronan JE Jr (1980). "Structural, enzymatic, and genetic studies of beta-ketoacyl-acyl carrier protein synthases I and II of Escherichia coli". J. Biol. Chem. 255 (24): 11949–56. PMID 7002930.
Price AC, Rock CO, White SW (2003). "The 1.3-Angstrom-resolution crystal structure of beta-ketoacyl-acyl carrier protein synthase II from Streptococcus pneumoniae". J. Bacteriol. 185 (14): 4136–43. doi:10.1128/JB.185.14.4136-4143.2003. PMC164876. PMID 12837788.
Garwin JL, Klages AL, Cronan JE Jr (1980). "Beta-ketoacyl-acyl carrier protein synthase II of Escherichia coli Evidence for function in the thermal regulation of fatty acid synthesis". J. Biol. Chem. 255 (8): 3263–5. PMID 6988423.
Magnuson K, Carey MR, Cronan JE Jr (1995). "The putative fabJ gene of Escherichia coli fatty acid synthesis is the fabF gene". J. Bacteriol. 177 (12): 3593–5. doi:10.1128/jb.177.12.3593-3595.1995. PMC177068. PMID 7768872.
Neidhardt, F.C. (Ed.), Escherichia coli and Salmonella: Cellular and Molecular Biology, 2nd ed., vol. 1, ASM Press, Washington, DC, 1996, p. 612-636.
beta, ketoacyl, synthase, this, article, about, specific, variant, enzyme, type, function, enzyme, general, beta, ketoacyl, synthase, enzymology, beta, ketoacyl, acyl, carrier, protein, synthase, enzyme, that, catalyzes, chemical, reactionbeta, ketoacyl, acyl,. This article is about the specific variant of the enzyme type II For the function and the enzyme in general see Beta ketoacyl ACP synthase In enzymology a beta ketoacyl acyl carrier protein synthase II EC 2 3 1 179 is an enzyme that catalyzes the chemical reactionBeta ketoacyl acyl carrier protein synthase IIIdentifiersEC no 2 3 1 179DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumSearchPMCarticlesPubMedarticlesNCBIproteins Z hexadec 11 enoyl acyl carrier protein malonyl acyl carrier protein displaystyle rightleftharpoons Z 3 oxooctadec 13 enoyl acyl carrier protein CO2 acyl carrier protein Thus the two substrates of this enzyme are Z hexadec 11 enoyl acyl carrier protein and malonyl acyl carrier protein whereas its 3 products are Z 3 oxooctadec 13 enoyl acyl carrier protein CO2 and acyl carrier protein This enzyme belongs to the family of transferases specifically those acyltransferases transferring groups other than aminoacyl groups The systematic name of this enzyme class is Z hexadec 11 enoyl acyl carrier protein malonyl acyl carrier pr otein C acyltransferase decarboxylating Other names in common use include KASII KAS II FabF 3 oxoacyl acyl carrier protein synthase I and beta ketoacyl ACP synthase II This enzyme participates in fatty acid biosynthesis References editD Agnolo G Rosenfeld IS Vagelos PR 1975 Multiple forms of beta ketoacyl acyl carrier protein synthetase in Escherichia coli J Biol Chem 250 14 5289 94 PMID 237914 Garwin JL Klages AL Cronan JE Jr 1980 Structural enzymatic and genetic studies of beta ketoacyl acyl carrier protein synthases I and II of Escherichia coli J Biol Chem 255 24 11949 56 PMID 7002930 Price AC Rock CO White SW 2003 The 1 3 Angstrom resolution crystal structure of beta ketoacyl acyl carrier protein synthase II from Streptococcus pneumoniae J Bacteriol 185 14 4136 43 doi 10 1128 JB 185 14 4136 4143 2003 PMC 164876 PMID 12837788 Garwin JL Klages AL Cronan JE Jr 1980 Beta ketoacyl acyl carrier protein synthase II of Escherichia coli Evidence for function in the thermal regulation of fatty acid synthesis J Biol Chem 255 8 3263 5 PMID 6988423 Magnuson K Carey MR Cronan JE Jr 1995 The putative fabJ gene of Escherichia coli fatty acid synthesis is the fabF gene J Bacteriol 177 12 3593 5 doi 10 1128 jb 177 12 3593 3595 1995 PMC 177068 PMID 7768872 Neidhardt F C Ed Escherichia coli and Salmonella Cellular and Molecular Biology 2nd ed vol 1 ASM Press Washington DC 1996 p 612 636 Portal nbsp Biology This EC 2 3 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Beta ketoacyl ACP synthase II amp oldid 1172341115, wikipedia, wiki, book, books, library,
