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Bernhard Keppler

Bernhard K. Keppler , born 1956 in Hockenheim,[1] is a German bioinorganic chemist and physician. He is chair of inorganic chemistry at the University of Vienna, head of the Institute of Inorganic Chemistry and dean of the Faculty of Chemistry.

Bernhard K. Keppler
NationalityGerman
Alma mater
AwardsHeinz Maier-Leibnitz-Preis (1991)
Scientific career
FieldsChemistry, Medicine
InstitutionsUniversity of Vienna
Notable studentsChristian Hartinger, Erwin Reisinger, Michael Reithofer, Christian Kowol, Georg Steinhauser

Education and career edit

Keppler earned his diploma's degree in chemistry in 1979, Ph.D. in chemistry from the University of Heidelberg in 1981, licence to practice medicine (approbation) in 1984 and second Ph.D. in medicine from German Cancer Research Center in 1986. He was promoted to university lecturer in inorganic chemistry in 1990 at the University of Heidelberg and assigned a chair in inorganic chemistry at University of Vienna with tenure in 1995.[2] He is dean of the Faculty of chemistry since 2008, head of the inter-university research cluster Translational Cancer Therapy Research (in cooperation with the Medical University of Vienna and Walter Berger [de]) and deputy head of the research network Chemistry, Microbiology and Environmental Systems Science (in cooperation with the Centre for Microbiology and Environmental Systems Science, University of Vienna, Michael Wagner (biologist) [de]).

Keppler is author and co-author of more than 550 papers in peer-reviewed journals, (~20.000 citations, H-index 74), 16 invited reviews, 50 book chapters, and numerous patents. He has edited several books (e.g. Metal Complexes in Cancer Chemotherapy, VCH, Weinheim, 1993) and co-authored the textbook Principles of Bioinorganic Chemistry (University Science Books, 1994) with other scientists. He currently serves as an Associate Editor of the Anticancer Research. Keppler serves or has served on the editorial boards of numerous other journals.

Research interests edit

Keppler's research activities are at the interface of inorganic chemistry and biology. A major focus of his activities is to understand, improve and develop anticancer drugs. He is a pioneer in investigating metal-based anticancer drugs and has developed multiple first-in-class compounds including KP1019, KP1339, and KP46 (IT-235, AP-002). BOLD-100, which is an anticancer drug related to the predecessors molecules KP1339 (NKP-1339, IT-139) and KP1019, is currently being investigated in clinical trials for advanced gastrointestinal cancers in combination with FOLFOX.[3] KP46 is currently being tested in patients with advanced solid tumors.[4] He also investigates environmental chemistry.

References edit

  1. ^ https://geschichte.univie.ac.at/de/personen/bernhard-keppler
  2. ^ Website Institute of Inorganic Chemistry
  3. ^ U.S. National Library of Medicine. (2020). BOLD-100 in combination with FOLFOX for the treatment of advanced solid tumours. https://clinicaltrials.gov/ct2/show/NCT04421820
  4. ^ U.S. National Library of Medicine. (2020). Evaluation of AP-002 in Patients with Solid Tumours. https://clinicaltrials.gov/ct2/show/NCT04143789

External links edit

  • University of Vienna - Institute of Inorganic Chemistry

bernhard, keppler, this, biography, living, person, needs, additional, citations, verification, please, help, adding, reliable, sources, contentious, material, about, living, persons, that, unsourced, poorly, sourced, must, removed, immediately, from, article,. This biography of a living person needs additional citations for verification Please help by adding reliable sources Contentious material about living persons that is unsourced or poorly sourced must be removed immediately from the article and its talk page especially if potentially libelous Find sources Bernhard Keppler news newspapers books scholar JSTOR June 2020 Learn how and when to remove this message Bernhard K Keppler born 1956 in Hockenheim 1 is a German bioinorganic chemist and physician He is chair of inorganic chemistry at the University of Vienna head of the Institute of Inorganic Chemistry and dean of the Faculty of Chemistry Bernhard K KepplerNationalityGermanAlma materUniversity of HeidelbergDKFZAwardsHeinz Maier Leibnitz Preis 1991 Scientific careerFieldsChemistry MedicineInstitutionsUniversity of ViennaNotable studentsChristian Hartinger Erwin Reisinger Michael Reithofer Christian Kowol Georg Steinhauser Contents 1 Education and career 2 Research interests 3 References 4 External linksEducation and career editKeppler earned his diploma s degree in chemistry in 1979 Ph D in chemistry from the University of Heidelberg in 1981 licence to practice medicine approbation in 1984 and second Ph D in medicine from German Cancer Research Center in 1986 He was promoted to university lecturer in inorganic chemistry in 1990 at the University of Heidelberg and assigned a chair in inorganic chemistry at University of Vienna with tenure in 1995 2 He is dean of the Faculty of chemistry since 2008 head of the inter university research cluster Translational Cancer Therapy Research in cooperation with the Medical University of Vienna and Walter Berger de and deputy head of the research network Chemistry Microbiology and Environmental Systems Science in cooperation with the Centre for Microbiology and Environmental Systems Science University of Vienna Michael Wagner biologist de Keppler is author and co author of more than 550 papers in peer reviewed journals 20 000 citations H index 74 16 invited reviews 50 book chapters and numerous patents He has edited several books e g Metal Complexes in Cancer Chemotherapy VCH Weinheim 1993 and co authored the textbook Principles of Bioinorganic Chemistry University Science Books 1994 with other scientists He currently serves as an Associate Editor of the Anticancer Research Keppler serves or has served on the editorial boards of numerous other journals Research interests editKeppler s research activities are at the interface of inorganic chemistry and biology A major focus of his activities is to understand improve and develop anticancer drugs He is a pioneer in investigating metal based anticancer drugs and has developed multiple first in class compounds including KP1019 KP1339 and KP46 IT 235 AP 002 BOLD 100 which is an anticancer drug related to the predecessors molecules KP1339 NKP 1339 IT 139 and KP1019 is currently being investigated in clinical trials for advanced gastrointestinal cancers in combination with FOLFOX 3 KP46 is currently being tested in patients with advanced solid tumors 4 He also investigates environmental chemistry References edit https geschichte univie ac at de personen bernhard keppler Website Institute of Inorganic Chemistry U S National Library of Medicine 2020 BOLD 100 in combination with FOLFOX for the treatment of advanced solid tumours https clinicaltrials gov ct2 show NCT04421820 U S National Library of Medicine 2020 Evaluation of AP 002 in Patients with Solid Tumours https clinicaltrials gov ct2 show NCT04143789External links editUniversity of Vienna Institute of Inorganic Chemistry Retrieved from https en wikipedia org w index php title Bernhard Keppler amp oldid 1193352035, wikipedia, wiki, book, books, library,

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